The birth of new neurons in the mouse hippocampus starts waning in early adulthood — well before cognitive decline becomes obvious — so the researchers wondered whether boosting Tet2 levels in the adult hippocampus could restore neurogenesis and potentially prevent
the onset of cognitive decline later in life.
Not exact matches
«We found that physical activity has the potential to preserve the volume
of the hippocampus in those with increased risk for Alzheimer's disease, which means we can possibly delay
cognitive decline and the
onset of dementia symptoms in these individuals.
Information from different types
of tests would help distinguish patients facing imminent
cognitive decline from those who may only have late
onset decline.
Carriers
of the apolipoprotein (ApoE) ɛ4 allele are at greater risk for developing late -
onset Alzheimer's disease (AD), develop AD at an earlier age, and experience a more severe
cognitive decline and shorter survival times.
As adults age, changes in physical health can be a natural part
of the process, as can
cognitive decline, which can range from normal change in cognition to the
onset of disorders such as dementia or Alzheimer's disease.
The potential for early diagnosis and delaying the
onset of motor or
cognitive decline by perhaps ten years is
of potentially profound importance in an aging society.»
Building on research that identified a rare genetic mutation in Italian people that leads to the early
onset of Alzheimer's and one in Icelandic people that delays the
onset of the condition, a researcher at the University
of British Columbia has discovered that using an enzymatic scissor the right way could stave off the
cognitive decline associated with the disease.
Buildup
of Aß into plaques plays a central role in the
onset of Alzheimer's, while the severity
of neuro - inflammation is believed to influence the rate
of cognitive decline from the disease.
Identifying the molecular triggers for the
onset of AD - related
cognitive decline presently requires the use
of suitable animal models, such as the 3xTg - AD mice, which develop both amyloid and tangle pathology.
Activities that stimulate the brain — such as learning a new language, playing brain - teasing games, or doing crossword puzzles — appear to delay the
onset of dementia, says Dr. Steinerman, although its still unclear if they can actually prevent or slow down
cognitive decline.
So many
of us associate aging with
cognitive decline, cardiovascular disease, arthritis, adult
onset diabetes, osteoporosis, chronic fatigue... Shall I...
The science is fairly conclusive that insufficient sleep — whether it be lack
of sleep in general or a shortage
of restorative sleep — has been correlated with earlier
onset of depression,
cognitive decline, diabetes, hypertension, obesity, and more.
we used to think
of early -
onset cognitive decline and dementias and mood disorders as being in their own bucket.