Not exact matches
A designer protein (brown and orange) fits snugly on top of the influenza virus's
hemagglutinin protein (green), which helps the virus latch
onto and infect cells.
These triple - mutant H7
hemagglutinins also successfully latched
onto cells in samples of human trachea tissue.
The 11 - page study, led by Yoshihiro Kawaoka of the University of Wisconsin, Madison, and the University of Tokyo, describes how the research group stitched a mutated version of a key viral protein called
hemagglutinin from the bird flu virus known as H5N1
onto the human H1N1 virus that caused a relatively mild pandemic in 2009.
Now, Skehel, along with colleagues at Harvard, Yale, and Emory University in Atlanta, Georgia, has used that sequence to build the virus's
hemagglutinin (HA)-- a protein that latches
onto receptors on the host cell surface — and determine its structure.