Sentences with phrase «open chromatin states»

Not exact matches

He said that the loss of Set2 keeps the chromatin in a more open state — not as compact as normal.

Having established some understanding of the open chromatin landscape in healthy mice, the researchers now hope to figure out how these relationships change with disease states.

While if the chromatin is found in another state, no binding occurs and, thus, also no chromatin opening, and ultimately no reprogramming.

Opening the way to accurately profile the chromatin states of in vivo stem cells, lineage progenitors and other scarce cell populations.

Chd1 may function in ESCs to maintain chromatin in an open (euchromatin) state and potentially promote pluripotency in this way.

According to this model, differentiation is a gradual transition from an open and permissive chromatin state in multipotent stem cells to a compacted cell - type specific chromatin state in differentiated cells.