Sentences with phrase «opiate exposure»

We note here that there were a small number of dyads in the CE group who also had prenatal opiate exposure (36 of 394; 9 % of the CE sample included in these analyses).

The results of this study revealed that in two cohorts of infant — mother dyads, one with prenatal cocaine or opiate exposure and a nonexposed control sample, neonatal behavioral characteristics and certain maternal psychological characteristics interacted to predict maternal ratings of temperament, and maternal self - reports of parenting stress.

Participants were drawn from the Maternal Lifestyle Study (MLS), an investigation of the effects of prenatal cocaine or opiate exposure on child outcome in a longitudinal follow - up from 1 month to 11 years in 1,388 children divided into an exposed group and a comparison group (Lester, 1998).

The identification of these opiate - induced changes offers the best hope for developing more effective pharmacological targets and therapies to prevent or reverse the effect of opiate exposure and addiction.

Interestingly, when Dr. Laviolette's team looked at dopamine signaling inside another brain region also involved in opiate related memory procession, and located closer to the surface of the brain, the mPFC, they found that this signaling was also switched by opiate exposure, but opposite to what was observed in the BLA.

Following chronic opiate exposure, however, opiate reward memory formation becomes independent of D1R, and rather depends on a second dopamine receptor, called D2r, and a protein called CaMKII.

More specifically, his work has shown that dopamine signalling in two connected brain regions involved in opiate - related memory processing, called the Basolateral Amygdala (BLA), a region deep within the brain, and the medial prefrontal cortex (mPFC), located near the surface of the brain, is switched by opiate exposure.

Not exact matches

As with neurobehavior, effects on breastfeeding are poorly studied, and more recent randomized controlled trials comparing exposure to epidural and opiate drugs are especially misleading because opiates have a well - recognized negative effect on early breastfeeding behavior and success.103 — 107

There are few studies of the condition of epidural babies at birth, and almost all of these compare babies born after epidurals with babies born after exposure to opiate drugs, which are known to cause drowsiness and difficulty with breathing.

In utero exposure to opiates (primarily methadone and heroin) has been shown in retrospective studies to be associated with an increased risk of SIDS.223, 224 With the exception of 1 study that did not show increased risk, 225 population - based studies have generally shown an increased risk with in utero cocaine exposure.226, — , 228 However, these studies did not control for confounding factors.

What do you need to know about adopting a child that may have prenatal exposure to opiates?

There was some evidence for an effect of exposure status (i.e., maternal cocaine or opiate use during pregnancy) on parenting stress, although this effect was not significant after controlling for maternal psychopathology (BSI scores).