New Insights on Pain and
Opioid Use in People With Sickle Cell Disease After Hematopoietic Stem Cell Transplant (March 12, 2018)
«This pragmatic trial will provide important information on ways to reduce or eliminate chronic
opioid use in those individuals who are not benefiting from opioids or wish to reduce the dose they are taking,» Archer said.
There is a shortage of high - quality evidence demonstrating the safety and effectiveness of long - term opioid therapy for the management of chronic pain, and to date, no large - scale studies have assessed strategies for managing and reducing chronic
opioid use in real - world clinical settings.
Longitudinal association between pain severity and subsequent
opioid use in prescription opioid dependent patients with chronic pain Griffin ML, McDermott KA, McHugh RK, Fitzmaurice GM, Jamison RN, Weiss RD. Drug and Alcohol Dependence.
The working group included five practicing hospitalists with expertise in
opioid use in the hospital setting and involvement in clinical research related to opioid use and outcomes in hospitalized patients.
In this study, Vanderbilt researchers wanted to see if the rise in infants born with neonatal abstinence syndrome correlated with the overall rapid increase in overall
opioid use in the U.S..
«We've always known that electronic dance music party attendees are at high risk for use of club drugs such as ecstasy or Molly, but we wanted to know the extent of
opioid use in this population,» said CDUHR researcher Joseph Palamar, PhD, MPH, the study's lead author and an associate professor of population health at NYU School of Medicine.
Of these 51 patients, 73 percent had received a naloxone rescue kit either in the emergency department or elsewhere, such as a detox facility, and approximately one third of the reported
opioid use in the last 30 days.
«The past few decades have seen an alarming rise in
opioid use in the United States, and the negative consequences are dramatically increasing,» says study co-author Hassan R. Mir, MD, MBA, associate professor of orthopaedics and rehabilitation at Vanderbilt Orthopaedic Institute.
- Increases in
opioid use in both blacks and whites; however, blacks were consistently prescribed fewer opioids than whites
«Negative emotions» linked to higher rates of
opioid use in sickle cell disease.»
In a Commentary in the same issue, Michael S. Leapman, MD, of the Department of Urology, Yale University School of Medicine, and Steven A. Kaplan, MD, of the Department of Urology, Icahn School of Medicine at Mount Sinai, offer some perspective on separating fact from fiction about
opioid use in urology.
Dr. Goesling and her team analyzed patterns of
opioid use in 574 patients undergoing knee or hip replacement surgery (arthroplasty).
The authors write that their study «provides reassurance that the individual risk of long - term
opioid use in opioid - naive surgical patients is low.
We have conducted numerous compliance checks to address the underage sale of alcohol and participated in workshops aimed at the prescription drug and
opioid use in our community.
ALBANY — At a bill signing last week on Long Island, Gov. Andrew Cuomo praised the efforts of his Republican colleagues in addressing the surge of heroin and
opioid use in the state.
As reported by the Times, the makers of Vivitrol have gained market share by portraying it as preferable to drugs like buprenorphine and methadone, which are
themselves opioids used in controlled doses to manage cravings.
OxyContin was the most highly reported
opioid used in this scene, followed by Vicodin, Percocet, codeine, and Purple Drank, also known as Sizzurp or Lean (which typically contains codeine syrup).
Not exact matches
While the innovation was initially
used for purposes such as injecting pain sufferers with powerful
opioids, it became a true game changer once insulin came on the scene
in 1921.
People
using the anti-diarrheal are recommended a maximum dose of eight milligrams per day OTC or 16 milligrams per day with a prescription; but some are taking upwards of 60 milligrams
in order to deal with
opioid withdrawal symptoms or to enhance their highs.
Taking dangerous quantities of the otherwise safe loperamide is one strategy being
used by people addicted to
opioid painkillers and other drugs since it can increase
opioid absorption
in the gut; the FDA says it is now working with loperamide manufacturers to change its packaging so that it comes with fewer doses and is thus harder to abuse.
Walmart's offer of free DisposeRX is just the latest
in a series of efforts by pharmacies to reduce the risk that
opioids will be diverted from their appropriate
use as painkillers and abused by either the original customer or another person.
In 2011, 31 % of prescription -
opioid - related overdose deaths involved these two kinds of drugs
used together, according to the National Institute on Drug Abuse.
The shift toward synthetics and
opioids has been motivated by both marijuana legalization and by changing drug -
use patterns
in the US
The US is suffering from a deadly
opioid epidemic, especially
in rural areas, thanks to the widespread
use of drugs like OxyContin as painkillers.
As the American Journal of Public Health put it
in 2009: «Purdue pursued an «aggressive» campaign to promote the
use of
opioids in general and OxyContin
in particular.»
The investigators told the AP they discovered two dozen pills
in an Aleve bottle
in Prince's home that had been labeled «Watson 385,» a stamp
used to ID pills that contain a mix of two other pain - relieving medications: hydrocodone (another powerful
opioid painkiller) and acetaminophen (the active ingredient
in Tylenol).
The agency warned last fall that there's little evidence to support kratom's
use as a «natural» pain relief alternative, and
in February, it issued a public health advisory saying that kratom compounds — ostensibly meant to replace addictive
opioid products — are actually
opioid products themselves.
However, Spicer then signaled that the White House sees recreational pot very differently, with the press secretary even attempting to link recreational
use of the drug to the abuse of
opioid drugs across the U.S. (
In fact, there has been little scientific evidence linking marijuana legalization to opioid use, with some studies actually showing a decrease in opioid overdoses in states where legal marijuana is available
In fact, there has been little scientific evidence linking marijuana legalization to
opioid use, with some studies actually showing a decrease
in opioid overdoses in states where legal marijuana is available
in opioid overdoses
in states where legal marijuana is available
in states where legal marijuana is available.)
One
in five inmates at the Hennepin County jail last December self - reported a history of
opioid use or abuse; an «astonishing» number said they'd overdosed, Sheriff Rich Stanek said Tuesday.
These seemingly harmless customer services are being
used as currency
in an unlikely and dangerous economy that is supporting the drug habits of people who suffer from
opioid addiction.
The deal included a variety of specifics, including new funding for disaster relief and
opioid treatment, but more specifically, it extended current spending levels until March 23 and trusted Congress to
use the intervening time to pass appropriations bills (or one big omnibus deal)
in accordance with the terms of the deal.
Several of the addiction professionals interviewed for this article sent lists of the proper terminology to
use when writing about
opioid addiction, and instructions on how to write about it
in a caring way.
Doctors are prescribing
opioids for patients»
use in committing suicide — federal law should put an end to it.
Workshop A: American Red Cross CPR / AED / FA Certification Course - $ 375 (non members $ 500 *) Workshop B: EBP WORKSHOP: Sport - Related Concussion Standard of Care Guidelines that Incorporate the 5th International Consensus Conference on Concussion
in Sport (2016) Recommendations - $ 35 (non members $ 60 *)- CLOSED Workshop C: Maximizing Employee Talents and Retention: Instituting Value Driven Leadership - $ 40 (non members $ 70 *) Workshop D: EBP WORKSHOP: The
Use of Neurodynamics
in the Treatment of Musculoskeletal Dysfunction - $ 105 (non members $ 180 *) Workshop E: EBP WORKSHOP:
Opioid Awareness and Narcan Training - $ 70 (non members $ 120 *) Workshop F: Forgotten Skills - Problem Based Learning Through Simulation - $ 80 (non members $ 140 *) Workshop G: EBP WORKSHOP: Evidence - Based Practice
in the Management of Sport - Related Concussion - $ 140 (non members $ 240 *) Workshop H: ATs Care: Assisting Individuals
in Crisis (Two day workshop - Continues on Sunday)- $ 195 (non members $ 195 *)
Heroin and
opioid use is a serious problem
in our community, and sticking our heads
in the sand doesn't help.
This risk can be reduced by discontinuing codeine after two to three days of
use and being aware of symptoms of potential
opioid toxicity
in both yourself and your baby.
«New guidance for safe
opioid prescribing for hospitalized patients with acute pain: 16 recommendations for improving safe
use of
opioids in noncancer patients during and after hospital stay stress limiting
use, educating patients.»
Among the label changes is a strengthened warning that breastfeeding is not recommended while
using medicines containing codeine or tramadol, because of the potential for serious adverse effects
in the infant due to
opioid overdose (1).
The U.S. Food and Drug Administration has strengthened the label warning to state that breastfeeding is not recommended while
using medicines containing codeine or tramadol because of the potential for serious adverse effects
in the infant due to
opioid overdose (76).
In a study looking at hospital discharge diagnostic codes, antepartum maternal
opioid use increased nearly fivefold from 2000 to 2009 (7).
Breastfeeding should be encouraged
in women who are stable on their
opioid agonist, who are not
using illicit drugs, and who have no other contraindications, such as HIV infection (73, 74).
As with systemic analgesia,
use of
opioids in an epidural block increases the risk that your baby will experience a change
in heart rate, breathing problems, drowsiness, reduced muscle tone, and reduced breastfeeding.
The Centers for Disease Control reports that non-medical
use of prescription
opioids has reached epidemic proportions
in the United States
in the past five years.
Trump, who as a candidate
used the Clinton Foundation to slam his opponent Hillary Clinton, heralded an
opioid program backed by the Clinton family foundation during a speech yesterday
in New Hampshire.
Hospitals
use these medications for
in - patients only, so those drugs operate
in a largely different market than the rogue prescription drugs, heroin and fentanyl fueling the nationwide
opioid epidemic, which claimed 268 lives
in Erie County alone last year.
We want to hear what you have to say about
opioid and heroin
use in our community.
A bill advancing
in the Assembly would bar insurers from requiring prior authorization for certain drugs
used in the treatment of
opioid addiction, including «long - acting injectable naltrexone.»
Fentanyl, an
opioid typically is
used to alleviate pain, has driven record fatal drug overdoses
in New York City.
Last week, the Governor and legislative leaders reached an agreement on multiple bills that include new programs and insurance reforms to improve treatment options for individuals suffering from heroin and
opioid addiction; measures to strengthen penalties and put
in place additional tools for law enforcement to crack down on the distribution of illegal drugs; provisions to ensure the proper and safe
use of naloxone, an overdose antidote; and support for enhanced public awareness campaigns to prevent drug abuse.