Dr. Otteson studied how retinal ganglion cells turn on and off the genes that regulate the normal patterns of connections during
optic nerve development.
Harald Junge, Ph.D., CU - Boulder: Determine the effects of trisomy 21 on
optic nerve development and function
Not exact matches
«There has always been this question of whether
optic nerve hypoplasia occurred during
development or if the visual system degenerated after the normal course of
development.
«In a mouse, the
optic nerve looks normal at birth, which is the equivalent of the third trimester of neonatal human
development,» said Fox.
Researchers from Massachusetts Eye and Ear / Harvard Medical School have identified inflammatory factors that cause
optic neuropathy in the back of the eye following implantation of a keratoprosthesis (KPro)-- similar to what glaucoma patients experience, without the rise of pressure in the eye — and have shown that blocking one of those factors, tumor necrosis factor alpha (TNFa), successfully halts the
development of
optic nerve damage in a mouse model.
We will leverage state - of - the - art bioinformatic and biological approaches for investigating how these factors interact in combination to regulate axon growth during RGC
development and test the potential of such factors for regenerating RGC axons in a rodent model of
optic nerve injury.
One study conducted in 2014 concluded that smokers with Graves» disease were more likely to experience rapid eye deterioration, including the
development of double vision, the constriction of eye movement, and irreversible
optic nerve damage.
Collie Eye Anomaly (CEA)-- a complex of congenital defects including choroidal hypoplasia, also called chorioretinal dysplasia — a thinning of the vascular tissue within the eye),
optic disc coloboma / staphloma — incomplete
development of the
optic nerve where it enters the eye, and retinal dysplasia or detachment — sections of retina, the vision reception tissue, that are not properly attached to the wall of the eye.