Sentences with phrase «optic nerve regeneration»

Our study identified the key cellular and genetic players that shape optic nerve regeneration and navigation.

Ultimately, our research will help elucidate factors that prevent proper optic nerve regeneration and guidance, and to find strategies that promote reconnection of damaged optic nerves and restore visual functions following optic nerve damage.

In the last several years, researchers have identified gene therapies that can promote optic nerve regeneration.

Second, we discovered that certain genes, namely Ncad expressed in the astrocytes, are important for optic nerve interaction with astrocytes, and for optic nerve regeneration.

Therefore, we reveal that optic nerve regeneration and navigation are in fact shaped by astrocytes.

Generous support from the Glaucoma Research Foundation allowed us to develop a strategy to comprehensively assess an entire class of biomolecules called lipids for differences that occur during optic nerve regeneration.

The project will identify a potential translational approach for promoting optic nerve regeneration, and also open a new avenue for identifying novel gene targets that can be manipulated to enhance optic nerve regeneration.

The proposed study aims to investigate two novel approaches for promoting long distance (ie, eye to brain) optic nerve regeneration.

First based on our completed genetic study we will test if pharmacological inhibition of an identified protein via direct eye injection can promote long distance optic nerve regeneration or whether, based on strong preliminary data, manipulation of another novel gene can induce such regeneration.

Not exact matches

There's no retinal ganglion cell regeneration or replacement after optic nerve injury.

In this study, we will examine whether glial cells and certain proteins secreted from these cells influence axon regeneration and guidance in the optic nerve in adult mice.

The researchers also reported that eliminating one of those genes, Rab27, led to regeneration of axons in the optic nerve or spinal cord of mice.