Sentences with phrase «optical mapping»
Optical mapping refers to a technique that uses light to capture and analyze the structure or arrangement of genes or DNA sequences within an organism. It helps scientists understand how genes are positioned and organized in an organism's genome. Full definition
Schwartz developed optical mapping while he was at New York University.
sciencemag.org
In today's Nature Genetics, researchers report that they have produced a so - called optical map of the parasite's 14 chromosomes, an achievement that should aid the ongoing effort to sequence the Plasmodium genome.
(2017) Combination of short - read, long - read, and optical mapping assemblies reveals large - scale tandem repeat arrays with population genetic implications.
The team used a combination of physical and optical mapping to arrive at the findings.
Optical mapping is «an incredibly fast and accurate way to authenticate the assembly» of pieces of sequence into a complete chromosome, says Leda Cummings, a molecular biologist who is sequencing part of the malarial genome at The Institute for Genomic Research in Rockville, Maryland.
The optical map, generated by David Schwartz of the University of Wisconsin, Madison, and his colleagues, should help in that assembly.
A sophisticated computer program then weaves together a picture of the DNA, showing the sites nicked by each enzyme, which are the landmarks on the optical map.
Yuste recently published research in the journal Neuron demonstrating the multiple connections between inhibitory and excitatory neurons using his optical mapping method.
His team, for example, developed an optical mapping method that involves bathing these brain slices with a chemical that deactivates neurons, and then uses lasers to stimulate them and visualize connections with light.