While Sentinel is safe to use in dogs at risk for MDRI - allele mutation (Australian Shepherds, Collies, Shelties, etc.), unless tested normal, caution is advised if your pet is also being given amiodarone (Cordarone), azole antifungals such as ketoconazole, carvedilol (Coreg), cyclosporine (Atopica), diltiazem (Cardizem), erythromycin (Ery - Tabs)
or clarithromycin (Biaxin), quinidine, spironolactone (Aldactone), tamoxifen, and verapamil (Calan).
Particularly the microbiota of the children who had received macrolide antibiotics, such as azithromycin
or clarithromycin, within the past two years differed from normal.
Triple therapy: Two antibiotics: Amoxicillin
or Metronidazole plus
Clarithromycin with a Proton Pump Inhibitor (While Proton Pump Inhibitors can make us more susceptible to H. Pylori by themselves, they work in synergy with antibiotics to reduce H. Pylori)