From a nosological perspective, the natural history of AUD represents a fundamental piece of the diagnostic validity puzzle.30 Uncovering a reliable and
orderly progression of symptoms would advance the construct validity of the AUD diagnosis.
Time, of course, only runs in one direction, and it seems to do so in
an orderly progression.
Cell cycle is controlled by a set of protein complexes consists of cyclins and cyclin dependant kinases (CDKs) together provide the cell
an orderly progression throughout the cycle [4].
Zygotes generate specific types of cells in
an orderly progression.