Not exact matches
The wife of ailing former Assembly Speaker Mel Miller has launched a desperate campaign to find him an
organ donor, saying he is suffering
from end stage kidney
disease and needs a transplant to save his life.
These techniques include: human tissue created by reprogramming cells
from people with the relevant
disease (dubbed «patient in a dish»); «body on a chip» devices, where human tissue samples on a silicon chip are linked by a circulating blood substitute; many computer modelling approaches, such as virtual
organs, virtual patients and virtual clinical trials; and microdosing studies, where tiny doses of drugs given to volunteers allow scientists to study their metabolism in humans, safely and with unsurpassed accuracy.
Traditionally,
organs from donors with hepatitis C were offered to recipients already infected with the
disease, because the virus could be transmitted during a transplant.
In humans, the goal of SCNT is «nonreproductive cloning» — making embryos, then removing stem cells
from the embryo and cultivating them to grow into tissues that could cure
diseases, replace
organs and heal injuries.
Hwang claimed to have perfected somatic cell nuclear transplant, a procedure in which genetic material is removed
from a donated egg and replaced with DNA
from the patient to create cloned cells that could regenerate
diseased tissues or
organs.
Mitochondrial defects are often observed in a variety of
diseases, including cancer, Alzheimer's
disease, and Parkinson's
disease, and are the hallmarks of a number of genetic mitochondrial disorders whose manifestations range
from muscle weakness to
organ failure.
Because the danger of melanoma comes
from its metastasis
from the skin to the vital
organs, being able to slow down or stop metastasis could turn a
disease that was often a death sentence into a manageable chronic illness with relatively little risk of death.
Over 6 million people in West and Central Africa suffer
from the
disease, which causes pain crises, widespread
organ damage and early mortality.
If researchers can unlock the secrets of this cellular process, therapies that replace
diseased cells with healthy ones may one day be possible — brain - cell transplants to combat Alzheimer's, for instance, or even the creation of whole
organs from scratch.
In a 14 - hour operation last July in Vienna, Austria, a team of nine surgeons led by Rolf Ewers removed the
diseased organ and replaced it with a tongue
from a brain - dead donor.
Projects range
from the development of artificial
organs and advanced diagnostics to groundbreaking cancer treatments and understanding the fundamental causes of
disease.
«For example, there is a huge amount of interest and excitement globally in growing cerebral organoids» — miniature brain - like
organs that can be studied in laboratory experiments — «
from stem cells to model human brain development and
disease mechanisms.
Leeper's team analyzed samples of arterial plaque
from people undergoing surgery for a clogged carotid artery and
from organ donors without cardiovascular
disease.
Aside
from a regenerative therapy to replace ailing
organs, the scientists add that the NPCs could be used to model
diseases in the lab.
«Although in our study we published the results obtained
from these colorectal samples, we are also studying the relationship between this protein and
diseases of the liver, the primary metabolic
organ,» explains Djouder.
The report «provides hope that even primitive tissues made
from stem cells will one day restore the function of dead or
diseased organs in patients,» he adds.
Knowing the origin of each cell and which genes control their normal function are the foundations for scientists to decipher the
disease process and eventually to find out how to guide the cells to self - repair or even to build up a brand new
organ using amended cells
from the patients.»
«Many patients who suffer
from untreatable chronic
diseases, including heart and kidney
diseases, are in waiting lists for limited
organ transplantation.
The team tested AC1903 in a rat model of kidney
disease caused by hypertension and saw the same results: The treatment preserved kidney podocytes and prevented the
organs from failing, even in advanced
disease.
Approaching aging
from the perspective of senescence at the levels of cells and
organs, the author discusses aging
diseases in the context of the tissues that they impact.
Moreover, while death and graft loss resulting
from organ rejection has improved in past 30 years, up to 42 % of non-graft related deaths are attributed to cardiovascular
disease according to a 2002 study by Vogt et al..
Older mice seem to benefit
from such an arrangement, developing healthier
organs and becoming protected
from age - related
disease.
In recent years, researchers in various fields have begun to grow tiny
organs from human stem cells to get a better view of development and
disease, and speed the search for new drugs.
These can lead to new traits, such as altered coloration, new susceptibility to
disease or protection
from it, or different shaped features (such as legs, antennae, toes or internal
organs).
Generated
from human pluripotent stem cells (hPSCs), the miniature
organs are being developed for their potential to study and treat liver
disease.
«In this study, we have a narrow focus on diabetes only,» wrote Tolstrup, «but since alcohol is related to more than 50 different
diseases and conditions — reflecting that alcohol affects virtually every
organ system of the body — any recommendations about how to drink and how much to drink should not be inferred
from this study or any study investigating associations between alcohol and a single outcome.»
We use physiology, histology, and molecular biology to understand development and
disease on a holistic basis, all the way
from the individual to the
organ to the tissue and finally to the molecules within cells.
Our aim is to develop a multi-scale mathematical model (ranging
from the molecular to the
organ scale) of the liver tissue that can predict alterations of
organ function consequent to molecular perturbations and
disease states.
This symposium will bring together researchers
from different fields to enhance our understanding of how organoids can be formed and maintained, how they can be used to study
disease and how we might eventually use them to regenerate and replace human
organ tissue.
Mitochondrial defects are often observed in a variety of
diseases, including cancer, Alzheimer's
disease, and Parkinson's
disease, and are the hallmarks of a number of untreatable genetic mitochondrial disorders whose manifestations range
from muscle weakness to
organ failure.
«This was very different
from all the other
organ systems where when you look at the tissue there's something to see that is the physical equivalent or correlate of the
disease,» Lichtman tells us.
Given the critical shortage of donor
organs to replace those damaged by accident or
disease, it has long been a goal of science to create human
organs from stem cells.
The MIT postdoc is studying this vital
organ and how the malaria parasite thrives in it to look for drugs that can stop the
disease from taking hold.
Their work could one day benefit patients who suffer
from inflammatory bowel
disease or
organ transplant rejection.
The Human
Organ - specific Molecule Electronic Repository (Homer) is a comprehensive database covering about 22809 genes / proteins detailed in and filtered
from expression and
disease - related databases such as, dbEST, TiSGeD, human plasma proteins (HPA), The Comparative Toxicogenomics Database (CTD) and Disease On
disease - related databases such as, dbEST, TiSGeD, human plasma proteins (HPA), The Comparative Toxicogenomics Database (CTD) and
Disease On
Disease Ontology.
This quality is even more crucial for building model
organs, because
disease treatments developed
from these models have to be safe and effective for humans.
Better genetically modified animals for
disease research and for
organ transplantation, and other research and therapeutic uses could arise
from the enhanced technology.
My husband, Richard, spent ten years in and out of the hospital with complications
from vascular Ehlers - Danlos syndrome, a rare and life - threatening connective tissue
disease that causes spontaneous ruptures of arteries and hollow
organs.
It was understandable: I was suffering
from stage 4 endometriosis, the most severe stage of the
disease, which means that it had spread all over my pelvic
organs.
Diverting attention
from the fact that iodine is the active ingredient in seaweed against the carcinogenic effect of estrogens on female reproductive
organs and against many other
diseases of the Western World, while pointing to some other factors in seaweed eliciting these beneficial effects.
The microbiome is a newly discovered
organ we need to support for sure, and
from the current
disease epidemics, we are obviously not doing a very good job.
Dr. Price showed us how certain nutrients, namely vitamins A and D found exclusively in animal foods like butter and
organ meats
from grass - fed animals, protect us
from cancer and heart
disease, and ensure that we have healthy children, generation after generation.
Methionine
from muscle meats may appear to contribute to
disease, for example, when the B vitamins, choline, and glycine found in bones, skin,
organ meats, egg yolks, legumes, and leafy greens are absent.
It will also help keep these two
organs healthy and free
from disease.
However, chronic and uncontrolled inflammation can cause damage to cells, tissue and
organs and result in a range of
diseases from autoimmune
diseases like Celiac
Disease and rheumatoid arthritis, to obesity and heart d
Disease and rheumatoid arthritis, to obesity and heart
diseasedisease.
It also claims to provide relief
from various
organ problems such as kidney problems, heart
diseases, and diabetes and even improving dental quality and bone strength.
Amongst several auxiliary discoveries such as a lack of cancers, zero facial deformation, zero cavities, rugged resistance to
disease and joyful exuberance for life... he noted that all of the strongest, healthiest and happiest tribes he studied ate a diet rich in saturated fats
from animal meat and
organs.
Popular for its wonderful benefits, this pose works amazingly for various
organs of the body and prevents it
from a number of
diseases and disorders.
** Some of the more serious side effects of antibiotics include: Candida, which is internal yeast overgrowth (fungal) that's linked to a «leaky gut syndrome» — Auto - immune
disease, increased permeability of the intestinal lining (all pose to seep toxins
from food, environment, cosmetics, etc. into internal
organs), digestive problems, depression, and IBS.
In autoimmune
disease, the body starts to target its own
organs since the body is unable to differentiate between a foreign invaders
from the body's own tissue.