Sentences with phrase «organelles responsible»

Not exact matches

The shape and chemical composition of these granules is identical to organelles found in cells called melanosomes; these being responsible for creating and storing the pigment melanin.

The researchers were able to show that a reduction in the number of ribosomes — organelles known as the protein factories of the cell — is responsible for the disruption in the formation of red blood cells found in patients with DBA.

Lysosomes are responsible for the turnover and clearance from cells of damaged organelles and protein aggregates.

The vacuolar - type H (+)- ATPase (V - ATPase) is responsible for the acidification of endosomes, lysosomes, and other intracellular organelles.

Certain particle compounds may directly generate ROS in vivo because of their surface chemistry (eg, metals, organic compounds, and semiquinones) or after bioactivation by cytochrome P450 systems (eg, polycyclic aromatic hydrocarbon conversion to quinones).6, 290 a, 290 b A particle surface or anions present on otherwise more inert particles may disrupt iron homeostasis in the lung and thereby also generate ROS via Fenton reactions.291 Other PM constituents may do so indirectly by the upregulation of endogenous cellular sources (eg, nicotinamide adenine dinucleotide phosphate [NADPH]-RRB- oxidase) 292,293 or by perturbing organelle function (eg, mitochondria) by taken - up PM components.261 Particle stimulation of irritant and afferent ANS fibers may also play a role in local and systemic oxidative stress formation.294 Given the rich antioxidant defenses in the lung fluid, secondarily generated oxidization products of endogenous molecules (eg, oxidized phospholipids, proteins) or a reduction in endogenous antioxidants per se may be responsible at least in part for the state of oxidative stress in the lungs (along with instigating the subsequent cellular responses) rather than ROS derived directly from PM and its constituents.

(In contrast to the role of autophagy in removal of defective organelles, the ubiquitin - proteasomal pathway is responsible for recycling damaged, long - lived muscular proteins that are not degraded through the autophagic / lysosomal pathway.)

Mitochondria are organelles in your cells that are responsible for producing energy and essentially lies at the heart of everything that occurs in your body.

And it is responsible for repairing damaged and defective organelles, cell membranes and cellular proteins...

However, an example of a factor that affects the ability of your muscles to absorb oxygen would be the extent of the blood capillary distribution at your muscles (more blood capillaries means more surface area for oxygen absorption), and an example of a factor that affects the ability of your muscles to use oxygen would be the mitochondrial density of your muscles (mitochondria are organelles in your cells that are primarily responsible for the cellular respiration process that uses oxygen to create ATP energy).

The pigment which is responsible for the skin colour, it is made from cytoplasmic organelles known as melanosomes.

It is caused by motility defects in specialized cell organelles called cilia that are responsible for the respiratory airway clearance, the propelled movement of sperm cells and the determination of the left - right asymmetry during embryo development.