Sentences with phrase «organoid culture system»

However, it is practically difficult to perform the rescue experiments in the organoid culture system because the lentivirus transfection is required for the gene transduction into the primary stem / progenitor cells and the APC gene (> 8.5 k base pairs) is too large to be cloned into the lentivirus.

Researchers modeled kidney development and injury in kidney organoids (shown here), demonstrating that the organoid culture system can be used to study mechanisms of human kidney development and toxicity.

«It took us a few years to optimize our 3D skin organoid culture system.»

Not exact matches

These so - called endometrial organoids promise to shed light onto the processes that occur during the monthly menstrual cycle and open up the possibility of studying diseases of the uterus, such as endometrial atrophy (thinning of the lining) or cancer, in a lab culture system.

2 - D cell - culture and mouse experiments also provided key evidence of the virus's modus operandi; although the rodent brain doesn't harbor the full contingent of human neural stem cells, it has blood vessels and immune - system components that organoids lack.

A team of researchers has developed a method to grow pancreatic tissue in a three - dimensional culture system, called organoids.

Learn the basics about how to incorporate this model system into your research, including how it compares to existing 3 - D cell culture and organoid models.

Consisting of optimized media and reagents, MimEX ™ Tissue Model Systems provides an alternative to current 3 - D cell culture modes, such as organoids, with the added benefit of...

For understanding the biology of gene - gene, gene - drug and gene - microenvironment interactions, a considerably broader range of in vitro and in vivo model systems is required — we are generating 1,000 organoid cultures from human cancers, characterising their genomes, functional dependencies and drug response, and we are expanding our in vivo models to study the interface between cancer and the immune system and microenvironment.

So she modified the Lancaster system to allow her organoids to survive and develop in culture for longer than anyone else — more than nine months.

A complex extracellular matrix is used for the maturation of CLCs; therefore, experience in hPSC culture and 3D organoid systems may be necessary for optimal results.