Sentences with phrase «organoids resembling»
Building on a long tradition of cell and developmental biology knowledge, organoids resembling a variety of human tissues have been generated.
https://www.embo-embl-symposia.org/
He and Clevers are trying to make the organoids resemble real cancer more closely by adding stroma and immune cells.
Not exact matches
The same observations were made in organoids (artificially grown masses of cells that resemble an organ) created from unique basal progenitor cells that were isolated from the gastroesophageal junction in mice and humans.
Other researchers grew organoids from induced pluripotent stem cells, which resemble embryonic stem cells but are grown from adult cells.
They found that, genetically speaking, their organoid model closely resembled fetal brain tissue at eight to nine weeks post-conception.
The other one, the finding by the Clevers group in Utrecht that adult Lgr5 + stem cells from the intestine, grown 3D in the presence of basement membrane matrix and a defined set of niche factors, can develop into ever - expanding, genome - stable 3D organoids that resemble the structure and function of the original intestinal epithelium (13 - 16).
Upon orthotopic transplantation into immunodeficient mice, these organoids form normal pancreatic ducts and acinar tissue resembling fetal human pancreas without evidence of tumour formation or transformation.
To make an organoid, cells are carefully coaxed to go through a process that resembles embryonic development.