There is evidence that rigid tumors shed more cells, which escape
the original tumor site and may lead to a greater chance of cancer spreading through metastasis.
When researchers injected fresh breast cancer cells in the side opposite
the original tumor site, the disease didn't recur in any of the mice, as the cancer was rejected by the immune system's memory.
Once they have consumed all the oxygen and nutrients in
the original tumor site, the cancer cells travel to other parts of the body (metastasize) to find more nourishment.
Not exact matches
When the dendritic cells are activated, they train T cells — their allies in the adaptive arm of the immune system — to attack cancer cells anywhere in the body, whether at the
site of the
original tumor or distant metastases.
But genetic similarities between metastasized and
original tumors suggest that multiple cells move together to remote
sites.
A lot needs to go right for a cancer cell to successfully leave the
site of its
original tumor, travel in the bloodstream, enter a distant organ and begin to colonize it.
Comparing the metastasized
tumors with the
original breast
tumors, the researchers were surprised to learn that multiple, slightly genetically different cells from the
original site had broken away together and established the new
tumors.
It is not easy to determine whether metastasis began early or late in the development of the primary
tumor or whether individual metastatic
sites were seeded directly from the
original tumor or from an intermediate
site.
In nearly three out of four patients the cancer causes metastasis, leaving the
original site of the
tumor and spreading to distant
sites in the body.
This long - term analysis confirms that treated
tumors did not reappear at the
original site; and late toxicity, beyond what was seen in the initial report, did not appear.
Metastatic disease refers to cancer that has spread through the blood or lymph system to form new
tumors in other parts of the body distinct from the
original site.
Metastasis is tһe process wһегеby cancer cells spread frоm thе
site оf thе
original tumor tо onе oг mогe otһеr places іn tһe body.
To avoid the risk of
tumor seeding (spillage of
tumor cell clusters and their subsequent growth at a
site adjacent to the
original tumor) through cystosyntesis (a procedure in which needle is inserted into the urinary bladder of an animal through the abdomen and a sample of urine is removed), urine may be collected by free catch or catheterization.
Depending on the location of the
tumor, radiation is used to prevent the recurrence of
tumors near the
site where the
original tumor was found.