Sentences with phrase «origins in the human genome»
What determines the replication program, i.e. the position, the time of firing and the efficiency of replication origins in the human genome?
https://science.institut-curie.org/ Not exact matches
In addition to sequencing the woolly mammoth genome, Hendrik has reconstructed the diets of extinct giant sloths, debunked a hypothesis about the origin of human immunodeficiency virus (HIV) and sequenced the genome of the bacterium that caused Black Death.
The study underlines the significance of southern African archaeological remains in defining human origins, and is published in the journal Genome Biology and Evolution, now online.
He says this idea has «very profound» implications for the debate over the origins of bacterial genes that are present in the human genome but absent in our closest relatives (Science, 8 June, p. 1903): The amount of conjugation Waters detected is «high enough to readily explain» the possible infiltration of bacterial genesinto our DNA, meaning that conjugation could have happened quickly enough to add genes only to humans, in the years since they split from the common ancestor they shared with chimpanzees.
The genome analysis also questions previous findings that modern humans populated Asia in two waves from their origin in Africa, finding instead a common origin for all populations in the Asia - Pacific region, dating back to a single out - of - Africa migration event.
After painstakingly piecing together the genome of the extinct strain, a team led by virologist Jeffery Taubenberger, then at the Armed Forces Institute of Pathology in Washington, D.C., concluded in 2005 that the virus most closely resembled viruses of avian origin; the team suggested it had become transmissible between humans after a couple of key changes (Science, 7 October 2005, p. 28).
Anthropologists and geneticists know that populations throughout the world migrated from Africa more than 60,000 years ago (see diagram), and that the human genome is at its most diverse in our continent of origin, but previous studies have only scratched the surface of African genetic diversity.
The accumulation of mutations in the human genome is at the origin of cancers, as well as the development of resistance to treatments.
Often more than one SNP differs between one population of humans and another — for example, mitochondrial genomes whose origin can be traced to France differ in a number of SNPs from those in people in Central Asia.
The influence of microbes is even inscribed on our genome: More than a third of human genes have their origins in bacteria.
Over the last 100 years, reconstructions of their appearance have slowly become «humanised» with each new revelation about their culture and physiology, culminating in the stunning discovery in 2010 that up to 4 % of the genome all modern humans of European and Asian origin carry Neanderthal DNA, as a result of interbreeding between the two species.
As we approach a point where some of the fundamental scientific questions are being resolved (e.g. the human genome, a unified theory and understanding of the origin of the universe), there has been an explosion of interest in the lives of great mathematicians and scientists.