Sentences with phrase «orthologous gene»

Positive selection in the human genome inferred from human — chimp — mouse orthologous gene alignments.

Positive selection in the human genome inferred from human — chimp — mouse orthologous gene alignments Clark, A. G., S. Glanowski, R. Nielsen, P. Thomas et al. 2003.

Inferring nonneutral evolution from human - chimp - mouse orthologous gene trios.

From these efforts, we identified a high - quality orthologous gene set across avian species, consisting of exons from 8251 syntenic protein - coding genes (~ 40 % of the proteome), introns from 2516 of these genes, and a nonoverlapping set of 3769 ultraconserved elements (UCEs) with ~ 1000 bp of flanking sequences.

Co-developed a method for determining orthologous genes in prokaryotes that can differentiate close paralogs using gene neighborhood context.

Co-developed a method for determining mammalian orthologous genes and their intron / exon boundaries using genome and mRNA data.

Functional annotation was done by comparing the reads against the Clusters of Orthologous Genes (COGs)[45] and TIGRFAMS [46] databases using RPSBLAST [47](E-value cut - off of 10 - 5).

Indeed, key aspects of most human disorders can be modeled in experimentally tractable organisms through the analysis of orthologous genes and pathways, using the genetic, biochemical and cell biological toolboxes that have been developed in each model organism.

By contrast, Pou5f1 - null mouse embryos maintained the expression of orthologous genes, and blastocyst development was established, but maintenance was compromised.

Not exact matches

For example, Bsl1 itself was highly increased in bsl1 - 1 mutants (corrected P = 0.003), as was a gene encoding a BR C - 6 oxidase orthologous to brassinosteroid deficient1 (brd1) from maize (Makarevitch et al., 2012) and rice (Hong et al., 2002)(SvBrd1; Sevir.9 G171700).

The new genes, however, also include 119 genes that are 1 - 1 orthologous to genes in P. vivax.

This is only done for the antibodies corresponding to genes where the mouse and human genes are orthologous.

Rapidly diverging short genes, even when they are evolutionarily orthologous to genes in other species, may be nearly impossible to classify as such.

Of these, 126 genes were orthologous to protein - coding genes in the human genome (hereafter, human BC susceptibility genes, hBCSGs), 70 % of which are previously reported cancer - associated genes, and ∼ 16 % are known BC suppressor genes.

RESULTS: Transcription of the MAOA gene in rhesus monkeys is modulated by an orthologous polymorphism (rhMAOA - LPR) in its upstream regulatory region.