Sentences with phrase «orthologous region»

In the present study, we used a combination of BAC clone contig construction, polymorphism analysis of DNA from congenic strains, and sequence mining of the human orthologous region to generate an integrated map of the Idd10 region on mouse chromosome 3.

Pepper explains, «One of the exciting things about this approach is that it employs a widely used, well - supported, off - the - shelf bioinformatics software known as Stacks (written by Julian Catchen at the University of Oregon) as a «filter» to enrich for pairs of fragments that are likely to be alleles of a single, orthologous region, rather than paralogs or homeologs.»

According to Pepper, «A problem arises when our computational methods accidentally align DNA regions that are duplicated within the genomes of the plants being studied, rather than mapping the orthologous regions between the plants.»

Not exact matches

«However, because SIF - seq only requires DNA sequence from a mammal and can be used in a variety of cell types, it should be possible to compare the neuronal enhancers present in a large genomic region from human to the neuronal enhancers present in the orthologous chimpanzee region.

Further exploring data amount, we used the assembled ~ 1.1 - billion - bp chicken genome (40) as a reference to generate a 322 - million - bp MULTIZ alignment of putatively orthologous genome regions across all species, comprising ~ 30 % of an average assembled avian genome and corresponding to the maximal orthologous sequence obtainable across all orders under our homology criteria (SM3).

RESULTS: Transcription of the MAOA gene in rhesus monkeys is modulated by an orthologous polymorphism (rhMAOA - LPR) in its upstream regulatory region.