Sentences with phrase «orthologs as»

Ward N, Moreno - Hagelsieb G. Quickly finding orthologs as reciprocal best hits with BLAT, LAST, and UBLAST: How much do we miss?.

Not exact matches

Future research will aim to describe the precise molecular mechanisms of action, as well as to generate other orthologs that boost efficacy while reducing side effects.

Of special note today: gut microbiota species expressing orthologs of human Ro60 might be involved in triggering and sustaining chronic autoimmunity in lupus; The portal vein blood microbiome in patients with liver cirrhosis; A randomized clinical study suggests dietary promotion of short chain fatty acid producing gut microbes as an effective treatment for type 2 diabetes; and the sexual dimorphism of root, flower and leaf microbiomes in the wild strawberry plant

Although CRISPR is incredibly useful for generating mutations by NHEJ and generating small mutations with HDR, when it comes to larger scale genome editing, such as replacement of a mouse gene with its human ortholog (greater than 5 kb), it remains to be seen whether CRISPR is as robust as conventional gene targeting.

* Commensal orthologs of the human autoantigen Ro60 as triggers of autoimmunity in lupus — Teri M. Greiling — Science Translational Medicine

The ortholog genes that were found to be associated with cartilage development, along with bmp which acts as a key member gene, are known to be involved in the Wnt signaling pathway (Kim et al., 2013; Lin & Hankenson, 2011).

As expected, an ortholog of AtDwf4 and OsDwf4 in S. viridis (SvDwf4; Sevir.9 G483600) was identified.

In addition, one of the genes identified — an ortholog of human COL2A1 is commonly used as a chondrocytic maker in the development of cartilage (Zaucke et al., 2001).

This gene was confirmed as the Nasonia ortholog of doublesex based on protein domains, expression pattern, sex specific splice forms, and experimental demonstration that splice forms are associated with sex in a gynandromorph producing line [18].