Some veterinarians may also give oseltamivir (such as over-the-counter Tamiflu ® for humans) in the thoughts that this medication may fight off the parvovirus directly; however, the benefits of
oseltamivir in parvo puppies is inconclusive.
Recently, veterinary interest has turned to
oseltamivir in the treatment of canine parvovirus, a life - threatening infection characterized by vomiting and bloody diarrhea.
There has been some interest in using
oseltamivir in infections other than parvovirus such as canine distemper, or even kennel cough.
«Although billions have been spent on
oseltamivir in the face of pandemic influenza,» the journal states, investigators «found that the public evidence base for this global public health drug was fragmented and inconsistent».
Not exact matches
Available data indicate that
oseltamivir is poorly excreted
in breast milk.
A new study published by researchers from the University of Illinois at Chicago suggests that the drug
oseltamivir — commonly known as Tamiflu — does not cause an increased risk of suicide
in pediatric patients.
Jefferson, a physician based
in Rome and prominent member of the Cochrane Collaboration, was charged with reviewing studies of the antiflu drug
oseltamivir, sold as Tamiflu, during the height of the avian flu scare
in 2005.
Yet
in his conclusion, Jefferson is less equivocal: «The remaining evidence suggests
oseltamivir did not reduce influenza related lower respiratory tract complications.»
Fortunately, studies so far have shown that
oseltamivir - resistant strains don't replicate very well, says epidemiologist Arnold Monto, an expert
in flu drugs at the University of Michigan
in Ann Arbor.
The H5N1 avian influenza strain developed strong resistance to
oseltamivir, better known as Tamiflu,
in two Vietnamese patients who died from the virus early this year, according to a new study.
The strains
in six other patients on
oseltamivir did not develop resistance.
In October, researchers reported the first known case of partial oseltamivir resistance in a 14 - year - old Vietnamese girl infected with H5N
In October, researchers reported the first known case of partial
oseltamivir resistance
in a 14 - year - old Vietnamese girl infected with H5N
in a 14 - year - old Vietnamese girl infected with H5N1.
Two drug classes: adamantanes (FDA approved
in 1966) and neuraminidase inhibitors (
oseltamivir, FDA approved
in 1999) represent two classes of drugs that target viral an ion channel and a cell surface antigen, respectively, hereby preventing or treating infection.
The key findings of both studies were
in agreement:
in order for a nascent pandemic to be controlled there needs to be 3 million courses of
oseltamivir (Tamiflu)-- the antiviral drug — available for the World Health Organization to mobilise and deploy internationally, immediately.
Both then introduced a pandemic virus and looked at whether it could be contained by giving a 10 - day prophylactic course of
oseltamivir to the contacts of every suspected flu patient — either by treating everyone
in their household, school, or workplace, or by simply giving it to anyone living within a certain radius.
But about 2 years ago, a seasonal strain appeared whose fitness is not diminished by the mutation — perhaps because other mutations compensate for it ---- which explains why that strain has spread so fast, even
in countries that use little
oseltamivir.
One such drug is the drug Tamiflu (
oseltamivir), used to treat early influenza infections
in humans.
To assist
in the treatment of canine parvovirus infection,
oseltamivir is given orally twice a day for 5 days.
Unlike other pneumonias or respiratory diseases, the anti-viral medication
oseltamivir (Tamiflu ®) can be helpful but only if used early
in the course of infection or to prevent infection
in exposed dogs.
There has been interest
in using
oseltamivir for canine influenza infection.
Remember, the goal of using
oseltamivir is to minimize the amount of virus
in the patient so that the immune system will have an easier job eradicating the infected cells.
Unnecessary use of anti-viral medications leads to resistance within the influenza virus population so it is important that medications such as
oseltamivir not be used for infections which are not life - threatening
in nature or which are likely to resolve with routine supportive care.