Sentences with word «osteoblast»

The accumulation of neutrophils expressing high levels of SiglecF, compared to other neutrophils, depended on the numbers of osteoblasts in the bones.
Burgener et al. «Fluoride Increases Tyrosine Kinase Activity in Osteoblast - Like Cells: Regulatory Role for the Stimulation of Cell Proliferation and Pi Transport Across the Plasma Membrane», Journal of Bone and Mineral Research, 10 (1): 164 - 171, 1995.
The WNT7B protein had no effect on the total activity of bone - degrading osteoclasts but substantially increased the number of bone - building osteoblast cells.
Scientists suspected that steroids interfere with the process of bone remodeling, in which cells called osteoclasts continuously break down old bone while other cells called osteoblasts build new bone.
Karsenty's team then focused in closer by looking at osteocalcin — a hormone produced by osteoblasts.
Preliminary study on the adhesion and proliferation of human osteoblasts on starch - based scaffolds.
Concluding that cordyceps enhance recovery from clinically - induced leucopenia, the team remarked that the substance achieves a positive effect on osteoblast differentiation — an essential factor in new bone formation — by acting on proteins and core binding factors that are needed to produce new bone cells.
Alsberg and colleagues mixed bovine chondrocytes, which fabricate cartilage, and bone - building osteoblasts from rats with a gelatinous matrix that contained a molecular growth signal.
Now, the Laboratory of Malaria Immunology Team at the Immunology Frontier Research Center (IFReC), Osaka University, headed by Professor Cevayir COBAN, have used mouse malaria models to show that robust immune activation and invasion of parasite by - products into the bone marrow during and after malaria infection leads to an adverse balance in bone homeostasis - a process usually tightly controlled - by bone forming osteoblasts and bone resorbing osteoclasts.
They used cytochalasin D, a naturally occurring substance found in mold, as a proxy to alter gene expression in the nuclei of mesenchymal stem cells to force them to become osteoblasts (bone cells).
Even when it is in its late stages, exercise helps to stimulate osteoblast activity in the bones.
Therefore, it is important to understand the spatial - temporal relationship and interaction between osteoblasts and terminally differentiated osteocytes (bone cells) and osteoclasts in vivo.
Mineralized human primary osteoblast matrices as a model system to analyse interactions of prostate cancer cells with the bone microenvironment.
Comparison of Human alveolar osteoblasts cultured on polymer - ceramic composite scaffolds and tissue culture plates.
In the next experiment, Karsenty looked for evidence of such signaling effects in osteoblasts from normal mice.
It works with osteoblast cells to build healthy bone tissue.
Cells known as osteoblasts make new bone; other cells, osteoclasts, destroy old bone.
«Our findings indicate the existence of long - distance interactions between lung tumors and bones: lung tumors remotely activate osteoblasts, and those bone cells, in turn, shape immunity by supplying tumors with cancer - promoting neutrophils,» says Pittet, who is an associate professor of Radiology at Harvard Medical School.
Human primary osteoblasts matrices as a model system for bone metastasis research.
Human alveolar osteoblasts interactions with PCL - TCP composite modified with collagen type I. Tissue Engineering, 12 (4), 1028 - 1028.
Aberrant gene expression profiles, during in vitro osteoblast differentiation, of telomerase deficient mouse bone marrow stromal stem cells (mBMSCs).
******* A similar trend was observed for genes involved in osteoblast proliferation (Tgfb1, Fgfr2 and Pdgfa) and bone mineral metabolism (Col1a1, Col2a1, Col1a2 and Col11a1).
You would basically see an increased activity of osteoblast which is your bone building cell.
Osteoblasts modulate osteoclast activity through secretion of the TNF family member RANKL (receptor activator of nuclear factor κB ligand).
The murine osteoblast cell line 7F2 (ATCC) was cultured in α - MEM with 10 % FBS.
The progenitor cells for osteoblasts are bone marrow mesenchymal stem cells.
The team was surprised to find that B12 - deficient mice had only one - third of the normal number of bone - creating osteoblast cells, but had no change in bone - degrading osteoclast cells.
«Using an intravital two - photon microscopy technique we developed, we investigated the communication between mature osteoblasts (mOBs) and mature osteoclasts (mOCs) in vivo,» study first author Masayuki Furuya explains.
The effect of Rhbmp - 2 on canine osteoblasts seeded onto 3D bioactive polycaprolactone scaffolds.
The effect of rhBMP - 2 on canine osteoblasts seeded onto 3D bioactive polycaprolactone scaffolds.
IL - 6 induced RANKL expression but suppressed OPG expression in the 7F2 osteoblast cell line (fig.
Protein kinase A regulates caspase - 1 via Ets - 1 in bone stromal cell - derived lesions: a link between cyclic AMP and pro-inflammatory pathways in osteoblast progenitors.
These products, including the major malarial by - product hemozoin, malarial proteins and as yet undefined virulence factors, induce MyD88 - dependent inflammatory responses in osteoclast and osteoblast precursors, leading to increased RANKL expression (a key molecule inducing osteoclast differentiation), and over-stimulation of osteoclastogenesis favoring bone resorption.»
Osteoblasts also migrate towards the top of the head in addition to undergoing oriented divisions.
Over time heavy impact work increases the activity of osteoblasts within your body which in turn leads to bigger and stronger bones — now this might not be something you've considered but when you get to middle aged, or elderly, and you fall over you might find yourself thankful for your years of pumping iron as you will likely walk away far less injured then your more sedentary friends.
Not only does lactoferrin increase osteoblast activity, it also reduces the formation of osteoclasts, and these bone cells help to increase bone turn - over or bone loss.
Gerard Karsenty at Columbia University in New York City and his colleagues applied osteoblasts — bone cells involved in building new bone — to cultures of cells taken from either the testes or ovaries of mice.
Varghese and her team showed that they could control the differentiation of human pluripotent stem cells into functional osteoblasts — bone - building cells — simply by adding the molecule adenosine to their growth medium.
Like living bone cells in the body, the resulting osteoblasts built bone tissues with blood vessels.
Besides osteoblasts, mesenchymal stem cells can also differentiate into the chondrocyte cells that make cartilage, the myocyte cells that help form muscles and the adipocytes, or fat cells.
Osteoblasts live only about three months and do not divide.
As the tissue heals, the bone graft is resorbed by osteoclasts (bone - consuming cells), and is eventually replaced by natural, healthy bone tissue via osteoblasts (bone - building cells).
Osteoblasts taken from the osteocalcin - deficient mice, however, had no impact.
Bone loss in models of leptin or leptin receptor deficiency has been linked with lower osteoblast activity (9, 14), suggesting that cellular leptin resistance in obesity might reduce bone formation.
Because osteoblasts readily adhere to this novel surface, dental implants coated with TiO2 nanotubes could significantly improve healing following dental implant surgery.
Ovine cortical osteoblasts outperform bone marrow cells in an ectopic bone assay.
Effect of collagen i and gelatin on the adhesion and mineralization of murine pre osteoblasts.
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