Sentences with phrase «osteoclast activity»

Lactoferrin has been shown to reduce osteoclast activity by an amazing 50 - 70 %, thus helping to prevent or even reverse osteoporosis.

Osteoblasts modulate osteoclast activity through secretion of the TNF family member RANKL (receptor activator of nuclear factor κB ligand).

Influences of age and mechanical stability on volume, microstructure, and mineralization of the fracture callus during bone healing: Is osteoclast activity the key to age - related impaired healing?

Previous studies suggest that microgravity activates osteoclasts, cells that control the breakdown of bone tissue, and the Medaka fish investigation examined the relationship between this increased osteoclast activity and reduced bone mineral density.

Further experimentation in vitro with human osteoclasts and in vivo in mice identified a portion of the Del - 1 protein that was particularly important for containing osteoclast activity, though additional parts of the molecule were needed to have the most potent inhibition of inflammation and bone loss.

They found evidence of Del - 1 in the same areas as osteoclast activity, then followed up by generating human and mouse osteoclasts in vitro and found Del - 1 mRNA and protein expressed at high levels.

I think when there's absolute Growth hormone deficiency you may have an increase in osteoclast activity.

But I don't think that there's any pituitary atrophy that takes place once you stop taking endogenous HGH so osteoclast activity should just stay being regulated by PTH and Estrogen levels.

Not exact matches

With this new understanding of how Del - 1 can inhibit periodontal bone loss — both by reducing inflammation and by restraining the activity of osteoclasts that resorb bone tissue — the researchers tested it, in a preclinical model of periodontitis observing that Del - 1 significantly reduced inflammation and tissue damage and that there was significantly less bone loss.

The WNT7B protein had no effect on the total activity of bone - degrading osteoclasts but substantially increased the number of bone - building osteoblast cells.

This indicates that microgravity's effect on bone density likely involves changes in mechanical force that lowers overall physical activity and therefore causes osteoclast activation

Genetic analysis also revealed significant increase in activity in two genes that may be involved in mitochondria function, suggesting that osteoclast activation might be linked to the reaction of mitochondria to microgravity.

Not only does lactoferrin increase osteoblast activity, it also reduces the formation of osteoclasts, and these bone cells help to increase bone turn - over or bone loss.

When it becomes more acidic, there's a higher rate of activity of cells called osteoclasts, which break down bone.

Estrogen suppresses the production of osteoclasts, the cells that break down the bone and slow the activity of existing osteoclasts.

To get slightly more scientific in terms of bone health, an acidic environment has been shown to encourage the activity of osteoclast cells.

Here's a quote: «Lactoferrin: Lactoferrin found in foods such as yogurt and kefir will stimulate new bone growth while preventing further breakdown of existing bone tissue, lactoferrin enhances both the growth and the activity of osteoblasts (the cells that build bone), and reduces the rate of bone cell death by 50 to 70 percent and decreases the development of osteoclasts, the cells responsible for breaking down bone.»