Sentences with phrase «osteosarcoma in»

Another common condition where amputation is discussed would be disease processes such as Osteosarcoma in which affected limb segments need to be amputated with clean margins and maximal limb length retention.

Osteosarcoma: Evaluation of a Recombinant, Attenuated Listeria Monocytogenes Expressing a Chimeric Human Her2 / neu Protein (ADXS31 - 164c) in Dogs With Osteosarcoma in the Adjuvant Setting

Dog Bone Tumour Treatment (canine osteosaracoma) Not rated yet Reader Question regarding Canine Osteosarcoma: My 6 year old fixed male Golden Retriever has just been diagnosed with osteosarcoma in the humerus...

Veterinary studies report that dogs and cats with osteosarcoma in the lower jaw have a better prognosis than those with cancer in the upper jaw, living approximately 9 months longer, with 1 - year survival rates ranging from 35 - to 71 %.

In May of 2005, my dog Raven was diagnosed with osteosarcoma in her left rear leg.

Among the more important collaborators will be Dr. Matthew Breen, whom I mentioned already, and Dr. Elaine Ostrander, who has been instrumental in creating the canine genetic map and is actively investigating the genetic basis of osteosarcoma in other breeds.

For more information on osteosarcoma in Scottish Deerhounds, or in other breeds of dog, please click on the links on the right.

Bandit was diagnosed with Osteosarcoma in April 2001 and lived almost six years from her initial diagnosis.

Two metabolites of diflubenzuron, para-chloroaniline (PCA) and 4 - clorophenylurea (CPU), increased the incidence of hemangiosarcoma and osteosarcoma in animal studies.

For example, osteosarcoma in breeds that showed reduced risk with neutering (Neopolitan mastiff, Airedale terrier, Bichon Frise, Basset hound, Bloodhound, Afghan hound, and Borzoi) all had zero cases in the NM sex class and one case in the M sex class which would correspond to a reduced risk with neutering.

Twelve years ago, Kaylee, my springer spaniel, developed osteosarcoma in one of her back legs and had it amputated.

Risk factors for the development of osteosarcoma in Rottweilers was studied and reported by Cooley DM et al (Can Epid Bio Prev 2002).

Ru et al. (Ep Sante Anim 1997 and Vet J 1998) first reported an increase in the risk of the bone cancer osteosarcoma in neutered as compared to intact dogs.

Tristan, a mixed - breed dog from Pittsburgh, Penn., was diagnosed with osteosarcoma in June 2014.

This study evaluated the effectiveness of Fosamax (alendronate) as a palliative therapy for osteosarcoma in Irish Wolfhounds.

There seems to be a higher incidence of osteosarcoma in male dogs.

It is considered similar to pediatric osteosarcoma in humans, a bone cancer that usually develops during the period of rapid growth that occurs in adolescence, as a teenager matures into an adult.

Samples from canine patients will not only allow the researchers to identify genes responsible for breed - specific susceptibilities (such as hemangiosarcoma in Clumber spaniels and osteosarcoma in Greyhounds), but also to translate these discoveries into new and more precise diagnostics and therapeutics for both canine and human cancer patients.

Let's take a look at Osteosarcoma in dogs for a clear example.

Our beloved Doberman, Jack, was diagnosed with osteosarcoma in his left leg.

For example, osteosarcoma in dogs is a type a cancer that has increased dramatically in recent years, and because it is more commonly found in larger breads, many falsely assume that genes are to blame.

Osteosarcoma in dogs is a malignant cancer of the bone that most commonly affects large and giant breeds such as Golden Retrievers, German Shepherds, Dobermans, Great Danes, Rottweilers, and Saint Bernards.

The Oncology Service of the Bailey Small Animal Teaching Hospital at Auburn University's College of Veterinary Medicine is offering a clinical trial to treat osteosarcoma in dogs.

It may represent an age - independent mutational mechanism that contributes to the development of osteosarcoma in children and adults alike.

Among some large - sized dog breeds the disease is much more common, but otherwise osteosarcoma in humans and dogs is very similar.

In 2011, I was diagnosed with Osteosarcoma in my leg,» she explained.

Not exact matches

Of the dogs stricken with osteosarcoma, 35 had the cancer in a leg which was subsequently amputated, followed by chemotherapy, which is the standard - of - care treatment; the dogs with elevated total cholesterol had a median survival time of 455 days, more than 200 days greater than the median survival time for dogs with normal cholesterol.

Leeper and collaborators at OSU and Iowa State University compared 64 dogs with osteosarcoma against two control groups: 30 dogs that had suffered traumatic bone fractures and 31 healthy dogs similar in age and weight to the animals with cancer.

Overexpression of ZMYND11 in an osteosarcoma cell line and a triple - negative breast cancer cell line inhibited tumor growth.

In their first set of experiments, Diehl's research team used chemicals to activate the UPR in osteosarcoma cellIn their first set of experiments, Diehl's research team used chemicals to activate the UPR in osteosarcoma cellin osteosarcoma cells.

To address these questions, Dang, Altman, and Hsieh collaborated with Penn colleague, Aalim Weljie, PhD, research assistant professor of Pharmacology, using an osteosarcoma cancer cell line to study the interaction of MYC and metabolism in cancer cells.

At this time, they have had success in trials with mice with a drug currently used for osteosarcoma, a bone cancer.

Starting in 2007, for example, Fan began testing an anti-cancer drug called PAC - 1 (developed by U. of I. chemistry professor Paul Hergenrother) in pet dogs with naturally occurring lymphomas and osteosarcomas.

For human controls these were Excision repair cross-complementing group 3 (ERCC3), Amplified in osteosarcoma (OS - 9), and Casein kinase - 1d (CSNK1D).

Beyond LFS, osteosarcoma is the most common type of bone cancer in all children, and after leukemia, the second leading cause of cancer death for them.

MicroRNA - 503 suppresses cell proliferation and invasion in osteosarcoma via targeting insulin - like growth factor 1 receptor.

Although improvements in therapeutic strategies were achieved, the outcome remains poor for most patients with metastatic or recurrent osteosarcoma.

Osteosarcoma is the most common primary bone malignancy in children and adolescents.

Forkhead box C1 is targeted by microRNA - 133b and promotes cell proliferation and migration in osteosarcoma.

Organization of the amplified type I interferon gene cluster and associated chromosome regions in the interphase nucleus of human osteosarcoma cells.

PAI1 stimulates assembly of the fibronectin matrix in osteosarcoma cells through crosstalk between the αvβ5 and α5β1 integrins.

Signaling pathways were inhibited in osteosarcoma and, especially, Wnt / β - catenin signal transduction in ovarian cancer cells and via GSK3 and STAT3 in CSCs and colon cancer [41, 47, 50, 52, 53].

Overexpression of Cox - 2 in Human Osteosarcoma Cells Decreases Proliferation and Increases Apoptosis

A total of 48 patients were included in the analysis, across six cohorts: liposarcoma (6 patients), vascular sarcomas including angiosarcoma and leiomyosarcoma (10 patients), undifferentiated pleomorphic sarcoma (5 patients), synovial sarcomas (5 patients), osteosarcomas (5 patients), and other sarcoma subtypes (17 patients).

Polo - like kinase 1 (PLK1), a critical cell cycle regulator, has been identified as a potential target in osteosarcoma (OS).

Homologous recombination deficiency (T - 3) was evident in many tumors, especially osteosarcomas and NBLs.

Cross-species identification of a plasma microRNA signature for detection, therapeutic monitoring, and prognosis in osteosarcoma.

26) Lockwood WW, Stack D, Morris T, Grehan D, O'Keane C, Cumiskey J, Lam WL, Squire JA, Thomas D, O'Sullivan M (2011) Cyclin E1 is amplified and over-expressed in osteosarcoma.

These findings may inform patient selection in future trials of IGF1R inhibitors in osteosarcoma.

We validate this observation using fluorescence in situ hybridization (FISH) in an additional 87 osteosarcomas, with IGF1 receptor (IGF1R) amplification observed in 14 % of tumours.