In addition, reduced barrier function can let bacteria and
other allergens enter the airways, increasing the risk of inflammation and infection.
Not exact matches
Once a grain of pollen, or
other allergen,
enters an allergic person's nose, mouth, or eyes that person's immune system overreacts to the harmless particles.
When
allergens enter the body, antigen presenting cells (immune cells that capture incoming substances and present them to
other immune cells, initiating a cascade of immune responses) at body surfaces, capture and present them to immune cells, particularly T cells (in a similar manner as if the
allergen was a foreign invading microbe).
The skin barrier — or stratum corneum — is what stands between us and the outside world, preventing environmental chemicals and biological irritants from
entering skin, including free radicals, bacteria,
other microbes,
allergens, toxic chemicals, ultraviolet light, injury and
other external assaults.
If the intestines are inflamed from some
other disease process, for example IBD (inflammatory bowel disease) in cats, the normal barrier lining the intestines is compromised and more
allergens can
enter the bloodstream.