Sentences with phrase «other aromatase»

For example, women whose cancer was no longer controlled by letrozole or other aromatase inhibitors, those who had already begun to receive chemotherapy, and premenopausal patients with metastatic disease.

Not exact matches

Other medications might include the aromatase inhibitor testolactone and the weak androgen danazol.

However, along with this seemingly linear storyline in which retinoids block progesterone's promotion of CK5 + cells, previous work in the lab of CU Cancer Center investigator Peter Kabos, MD, and others shows that breast cancers treated with anti-estrogen drugs like tamoxifen or aromatase inhibitors show an increased population of CK5 + cells — it is as if these therapies remove the roadblock of estrogen - dependent cells, leaving CK5 + cells to proliferate.

In other patients, using aromatase inhibitors to block estrogen synthesis and allow HOXC10 and other genes to destroy the cancer works in the short term,» said Dr. Oesterreich.

That meant the risk of disease recurrence and new cancer was 34 percent lower among women who continued the aromatase inhibitor for 10 years compared with the other group, researchers said.

The inability to detoxify estrogen goes hand in hand with hypothyroidism, but there are other factors that can also increase estrogen production within the tissue itself such as aromatase activity.

Estrogen is often overproduced in hypothyroidism by increased production of aromatase, which converts testosterone and other androgens into estrogen.

In a study published in the Journal of Steroid Biochemical Molecular Biology (1993; Vol 46, No 3), chrysin and 10 other flavonoids were compared to an aromatase - inhibiting drug (aminoglutethimide).