Sentences with phrase «other bone cells»

The team discovered that a certain subset of cartilage - making cells, known as chondrocytes, replicate themselves, make other bone cells and drive bone growth — findings that could lead to new treatments for children with facial deformities who normally have to wait until adulthood for corrective surgery.

«The bone lining cells also make sense as gatekeepers or mediators for the effect of the bound hormone because of their position on the bone and their connection to the other bone cells,» says Erben.

Not exact matches

Other exciting developments: Baby's bone marrow begins making white blood cell, the pituitary gland starts to secrete hormones, and your baby's vocal cords form.

These unformed stem cells have the ability to turn into mature blood cells — and could save the life of someone who needs a bone marrow transplant, and possibly other diseases, since stem - cell research remains in its infancy, really.

Stem cells have also been identified in human milk, and have the potential to differentiate into mammary epithelial lineages under mammary differentiation conditions in vitro, as well as other cell types in corresponding microenvironments, including bone cells, brain cells, liver cells, pancreatic beta cells and heart cells.

In fact, it is the most abundant mineral in our bodies, with over 99 per cent stored in our bones and teeth and the rest stored in other parts of the body, including muscles, blood and the fluid in between cells, where it acts as a «messenger» for the central nervous system.

«On the other hand, if we overexpress this enzyme in prostate cancer cells, we found increased bone metastasis in mice.»

The lab that I work in is primarily interested in understanding how and why certain cancers are more likely to spread to the skeleton, and my personal project has focused on uncovering new mechanisms that the cancer cells use to communicate with other cells in the bone.

There are details of the structure of the living cell, essential features in the composition of metals, cotton, silk, rubber, paint, bone, nerve, and a thousand other things which are hidden even from the microscope, and must always remain so hidden because the failure does not lie with the skill of the optician but with the incapacity of light itself.

These cells orchestrate the development of the jaws and other facial bones as well as the heart and its major vessels in a growing embryo, says Benner.

Other adult stems cells exist — such as hematopoietic stem cells, which can generate all types of blood cell and mesenchymal stem cells, which can turn into bone, fat and cartilage cells.

There are specific cells that form bone and other cells that resorb it.

«We believe that small subsets of metastatic tumor cells have the ability to adopt the mechanisms used by immune cells to exit the blood vessels into the lungs, the bone marrow, the brain, and other organs.

The back - and - forth attachment and removal of methyl groups also fine - tunes gene expression in stem cells, which can mature, specialize and multiply to become muscle, bone, nerve, or other cell types.

To gauge the impact of hemozoin and other parasite wastes, the team cultured bone marrow cells in a cocktail of these substances.

We don't need to use a cocktail of small molecules, growth factors or other supplements to create a population of bone cells from human pluripotent stem cells like induced pluripotent stem cells,» Varghese said.

«When we transplanted our labeled blood stem cells from the bone marrow into other mice, only a few stem cells were active in the recipients, and many stem cells were lost,» Rodewald explains.

Cells known as osteoblasts make new bone; other cells, osteoclasts, destroy old Cells known as osteoblasts make new bone; other cells, osteoclasts, destroy old cells, osteoclasts, destroy old bone.

The stem cells used, mesenchymal stem cells (MSCs), are thought to elicit a less vigorous immune reaction than blood stem cells, and MSCs can develop into bone, along with other connective tissues.

Still, a few stem cell therapies have now been approved, such as a treatment available in India that takes stem cells from the patient's eye in order to regrow the surface of their cornea, and a US product based on other people's bone stem cells.

Therefore, they not only kill cancer cells but also are toxic to other rapidly proliferating cells such as those in hair follicles and bone marrow.

«We found that harmine, likely by interacting with DYRK1A, increases levels of other known drivers of cell division,» said Peng Wang, PhD, Assistant Professor of Medicine, Endocrinology, Diabetes, and Bone Disease at the Icahn School of Medicine and first author of the paper.

On the other hand, the problem is, you know, with embryonic stem cells, they haven't been able to get stem cell lines from livestock animals that can proliferate in that way, without just sort of veering up in their own direction and turning into, instead of muscle, turning into brain tissue or bone tissue or something else.

After other researchers reported that bone marrow stem cell therapy led to a modest but promising 5 percent improvement in the regeneration of sensory nerve fibers in rats with spinal cord injuries, he performed a critical reality check.

However, these poisons can also do significant harm to other dividing cells such as those found in the stomach lining and in hair and nail follicles, as well as the blood and immune stem cells in the bone marrow.

• A Yale research team led by Diane Krause turned a single stem cell from the bone marrow of an adult mouse into lung, liver, intestinal, and skin cells for other mice.

This shows promise for breast cancer patients as diagnosing and treating the breast cancer at early stages means there is a greater chance of preventing cancer cells spreading to other tissues, such as the lungs, brain and bone.

These findings may help explain why some people with mutations in certain ribosomal protein genes develop conditions such as Diamond - Blackfan anemia — a blood disorder in which the bone marrow doesn't make enough red blood cells — but don't have problems in other body tissues, Ware says.

The paste's main advantage over other fracture treatments is that it is fully biocompatible: bone cells grow into the solidified paste, and the implant is eventually replaced by living bone.

Created with other blood cells in the bone marrow, they interfere with activation and proliferation of T cells, the immune system's attack cells.

«Since patients with many types of cancer have elevated levels of myeloisd cells in their blood, it's possible that other tumors could have a similar interaction with bone to increase myeloid cell production.»

Previous research shows that certain fat cells can be coaxed to turn into other tissue, including skin, bone, and cartilage.

If each cell is genetically identical, however, how does it grow to be a skin, blood, nerve, bone or other type of cell?

Metastasized cancer cells then stimulate other cells in the bones to degrade the bone tissue, a mechanism also believed to take place in OS.

The two plots in the Nature paper show flow cytometry data - a counting up of cells - after exposure to other cells in bone marrow taken from younger and older mice.

An artificial bioreactor may in future supply limitless quantities of blood and bone marrow cells for transplantation into people with leukaemia and other blood diseases.

In a healthy person bone marrow acts as a sort of factory of stem cells, the vital cells that mature and divide to form other essential blood cells throughout the body.

«Future studies are needed to answer whether other hormones also influence bone turnover via this cell type or if they use other cells.

Contained in spongy bones, the bone marrow microenvironment and its «niches» support production of platelets and other blood cells.

To achieve this, we selectively deliver proteins and other molecules that change Wnt signalling specifically to stem cells, particularly in the bone.

The two cell types formed structures reminiscent of bone growth plates — cartilage on one side, bone and marrow on the other, they report online 6 September in the Proceedings of the National Academy of Sciences.

For his dissertation research, which he'll begin this fall, he will try to untangle the network of proteins that controls how mesenchymal stem cells differentiate into bone, muscle, and other tissue.

He notes, however, that other attempts to stimulate bone growth in mice by manipulating cell signaling proteins have produced denser than normal bones — and he's surprised that Helms's team didn't see the same.

The authors write that PBSCs are still used, despite disadvantages in patients with bone marrow failure, most likely because centers obtain PBSCs routinely for other indications and cell separators are available at any transplant center.

Schweitzer soon extracted similar stretchy vessels from two other tyrannosaurs and found hints of preserved bone cells in a duck - billed dinosaur.

More than 40 clinical trials are underway using other kinds of stem cells, mainly bone marrow cells from the patients themselves.

The mechanism is known as NMD (nonsense - mediated mRNA decay), and scientists found that exposing breast cancer cells to a molecule that inhibits NMD prior to treatment with doxorubicin, a drug used to treat leukemia, breast, bone, lung and other cancers, hastens cell death.

To test whether adipose tissue F4 / 80 + cells shared a common bone marrow origin with other tissue macrophage populations, we transplanted bone marrow from C57BL / 6J mice expressing the CD45.1 leukocyte marker into 6 - week - old lethally irradiated C57BL / 6J mice expressing the CD45.2 leukocyte marker.

During a viral infection, the body needs various defense mechanisms — amongst other things, a large number of white blood cells (leukocytes) must be produced in the bone marrow within a short period of time.

Although rare, her cancer showed similarities to other more common forms of cancer, including sarcoma, cancer of the bone, and neuroblastoma, a cancer of the nerve cells that are more common in children.