Although antipsychotic drugs are among the most widely prescribed medications, individuals with schizophrenia, bipolar disorder and autism - spectrum disorders often experience severe side effects because the drugs interact with dozens of
other brain receptors.
Not exact matches
In
other words, chocolate may slow the speed at which the
receptor sucks up the serotonin in your
brain, which enables you to feel happier for longer bouts of time.
Vivitrol, on the
other hand, is designed to block opioid
receptors in the
brain, which prevents users from getting high and, in theory, helps break their addiction.
As they studied
brain activity in the knockout mice, the researchers also found prominent changes in a
receptor in the
brain known as mGluR5 and
other proteins that support the function of neurons and synapses, said co-lead author Xiaoming Wang, M.D., Ph.D., senior research associate in Duke's department of pediatrics.
The cerebellum has the highest density of glucocorticoid
receptors, which are involved in stress responses, than any
other place in the
brain.
This works as
other general anesthetics work, acting on
receptors in the
brain — possibly the GABA [gamma - aminobutyric acid]
receptors, because that is a mechanism for a lot of sleepiness in the
brain.
PET scans have demonstrated that some individuals have twice as many mu opiate
receptors in certain
brain regions as
others.
At around age 10, spurred by sex steroids and
other important growth hormones, the
brain starts to prune dopamine
receptors in the striatum, an important part of the basal ganglia, and in the prefrontal cortex.
Despite all of these negative effects they have very little benefit in improving psychosis in people with dementia Pimavanserin works differently to
other antipsychotics, by blocking a very specific nerve
receptor (THT2A) in the
brain.
Other companies, including Pfizer, based in New York, have invested in nicotinic -
receptor modulators to treat Alzheimer's disease and attention - deficit hyperactivity disorder (see Aiming at the
brain's nicotine
receptors).
LPA
receptors are all over neural progenitor cells, which go on to form neurons and
other types of cells in a young
brain.
The
brain stem and certain
other parts of the
brain are particularly rich in the
receptors that attach to opioids.
By pairing a
receptor that targets neurons with a molecule that degrades the main component of Alzheimer's plaques, the biologists were able to substantially dissolve these plaques in mice
brains and human
brain tissue, offering a potential mechanism for treating the debilitating disease, as well as
other conditions that involve either the
brain or the eyes.
«The
brain along with the reproductive system and every
other cell in your body is exquisitely sensitive to exceedingly small changes in estrogen and
other sex hormones, and the fact that the environment is full of chemicals that can activate estrogen
receptors means this phenomenally sensitive system is being perturbed constantly by environmental factors.»
Although fetuses start forming pain
receptors eight weeks into development, the thalamus, the part of the
brain that routes information to
other areas, doesn't form for 20 more weeks.
Novitch's UCLA lab group has likewise used its
brain organoids to pinpoint additional
receptors by which the virus may gain entry into neural stem cells, and identified a few
other drug leads for blocking infection.
In the absence of that protein,
other proteins involved in transmitting signals between neurons in the
brain are overproduced, notably mGluR5, a
receptor for the neurotransmitter glutamate.
Receptors facilitate chemical and electrical signals between neurons in the
brain, allowing those neurons to communicate with each
other.
The molecule can influence signals sent by a number of
other receptors in the
brain, many involved in pain and inflammation.
She notes that there are
other studies underway to figure out the
receptors in the
brain that are affected by stimuli like the odor of androstadienone, which could help determine the reason for the corresponding hormone hikes.
Instead, it acts on chemicals in the
brain, primarily
receptors for serotonin, a chemical messenger involved in mood, among many
other things.
And they found that, in turn, hormonelike substances called prostaglandins were secreted along with
other substances that, combined with the dilation of scalp arteries, stimulate the
brain's pain
receptors.
The endothelial cells have a
receptor for transferrin that acts like a gatekeeper: When transferrin binds to a
receptor on the blood side of the barrier, the endothelial cell transports it (and its iron cargo) to the
other side and spits it out into the
brain.
The
brains of montane voles, on the
other hand, have far fewer vasopressin
receptors and therefore make much weaker connections between pair bonding and pleasure.
These substitute drugs can also attach to opioid
receptors in the
brain, blocking access to
other, more deadly drugs.
They gave some of the rats flutamide, which blocks testosterone from activating
receptors in the
brain, and gave
others tamoxifen, which blocks estrogen
receptors, finding that the drugs lessen the anxious behavior in the rats.
The weight - reducing effects of leptin, a hormone that signals the size of the body's fat stores, result from interaction with a
receptor in the
brain's hypothalamus and
other tissues, HHMI scientists...
This slide nicely shows this particular
receptor, and that it's typically found in different regions of this
brain, but also found in
other tissues.
When certain chemicals in food or
other materials trigger a response in these
receptors, the
brain detects one or more flavors — sweet, sour, salty, bitter or umami.
Previous research by Dixson and
others has shown that as water becomes more acidic, it begins to interfere with a structure — called a
receptor — on cells in a fish's
brain.
The combination technique developed by Yang et al. will likely be used by
other scientists to further study the role of NMDA
receptors in specific
brain cells during addiction and normal
brain activity.
Other studies show that another compound in dark chocolate, called anandamide, activates the same
brain receptors as marijuana.
When
receptor doors close, there's inflammation, there's a shut down of cell function, and ****
other hormones, like Thyroid, Sex, and Leptin (which tells our
brain we're full) are prevented from entering and delivering their messages.
In certain women with PMS, progesterone after ovulation changes the GABA
receptor in your
brain so that it is no longer able to respond to progesterone and
other neurosteroids.
The male may still be trying to mount
other dogs for a few months as his testosterone bound by
receptors in his
brain gradually reduces.
However, with the canonization of Duchamp following his death in 1968, presentational art began proliferating, and, like a drug, it soon swamped the
brain's
receptors for
other kinds of sensations.
DRD2 codes for the D2
receptor and is found throughout the body, but especially in the striatum, the pituitary gland, the amygdala, the caudatus, the putamen, and
other regions of the
brain [22].