The virus is engineered to grow in cancer cells, destroy these tumors, and then spread to
other cancer sites.
Not exact matches
BioNTech, which has around 700 employees at
sites in Germany — more than any
other unlisted biotech firm in Europe — is also working on
other cancer - fighting technologies, including antibodies, cell therapies and small molecules.
Metastasis involves clumps of
cancer cells becoming detached and moving through the blood stream or the lymphatic system to
other areas, where they become attached to a new
site and continue growing.
The bill would extend the current statute of limitations law, to allow a three year window between when New Yorkers find that their water has been contaminated with toxins linked to
cancer and
other disease, and a Superfund
site has been declared, and when they can file a lawsuit.
Wong and his lab want to see if edelfosine could be incorporated into future clinical research focused on
other tumor
sites such as lung, ovarian and pancreatic
cancers.
Metastasis is the spread of
cancer from its primary
site to
other places in the body (e.g., brain, liver).
Once they have consumed all the oxygen and nutrients in the original tumor
site, the
cancer cells travel to
other parts of the body (metastasize) to find more nourishment.
Most of these deaths were because the
cancer had spread to
other organ
sites.
«Urologists tend to prefer to forgo adjuvant radiation therapy, because they fear the side effects, and radiation oncologists tend to prefer offering adjuvant radiation therapy because they fear the risk of metastasis [
cancer spreading to
other sites in the body],» Showalter said.
Some studies suggest there's a connection between shortened telomeres and some types of
cancer, but not
other types of
cancer (see a comprehensive listing of papers on the Telome Health
site).
A new digital reconstruction of the chromosomes of the ancestor of all placental mammals reveals that these tightly packed structures of DNA and proteins have become scrambled over time — a finding that may help pinpoint possible problem
sites in our genomes that underlie
cancer and
other disease.
The trial, which will be led by Maria R. Baer, MD, professor of medicine at UM SOM and director of hematologic malignancies at UMGCCC, will enroll patients at the Greenebaum Comprehensive
Cancer Center and several
other sites.
So PSA is great tool after prostatectomy in terms of predicting recurrence if the level starts to climb up again, indicating that the
cancer has spread to
other sites in the body.
Like pancreatic
cancer,
cancer of the ovaries is notorious for being discovered at a relatively late stage — after it has spread to
other sites in the body.
Cancer can become deadly after surgery to remove a primary tumor because of the possibility of recurrence of the cancer at the surgery site and other parts of the
Cancer can become deadly after surgery to remove a primary tumor because of the possibility of recurrence of the
cancer at the surgery site and other parts of the
cancer at the surgery
site and
other parts of the body.
For each of these
cancer sites, the researchers calculated important regional and county differences in advanced stage of diagnosis, which takes into account the growth and size of the tumor and whether it has spread to the lymph nodes or
other organs.
Metastasis, or
cancer spread by the formation of tumors at new
sites, is generally what makes
cancers deadly because surgery and
other treatments are unlikely to find and destroy every
cancer cell.
Fully understanding this process may present new target
sites for drugs and may lead to better treatments for neurological diseases,
cancers and
other disorders.
If the researchers find this unique profile is linked to
cancer development, they believe they could potentially use the microbiota in
other sites such as the vagina or colon as a screening tool.
The process, which located a genetic
site for the most common form of prostate
cancer, has potential for developing precision therapy for other cancers, such as breast, brain and colorectal, say researchers at The University of Texas MD Anderson Cancer C
cancer, has potential for developing precision therapy for
other cancers, such as breast, brain and colorectal, say researchers at The University of Texas MD Anderson
Cancer C
Cancer Center.
The team chose to compare breast tissue from healthy individuals with tumor samples taken from breast
cancer patients — including both primary tumors that had not spread from the breast to
other body
sites, and highly aggressive, metastatic tumors.
Metastasis (the spread of
cancer from its primary
site to
other places in the body) to the ovaries can result in Krukenberg tumors.
This allows
cancer cells to break off from tumors, spread throughout the body (in blood or
other fluid) and form new tumors at distant
sites — a process called metastasis.
The idea is that the drug, being within the nano - hydrogels, is transported directly to
cancer cells where it can be released without damaging
other parts of the body, because hydrogels offer the possibility of dosing a myriad of active substances on the
site desired and can be administered as dry or swollen hydrogels by different routes: oral, nasal, buccal, rectal, transdermal, vaginal, ocular and parental.
«Most
cancers kill their victims by metastasis, wherein cancerous cells move from the primary
site to
other places in the body.
The cell changes, known as an epithelial to mesenchymal transition, or EMT, are normal and helpful during wound healing, but problematic when
cancer cells spread from the primary tumor
site to
other sites in the body.
One drug attacks
cancer cells; the
other inhibits
cancer cell formation and the growth of blood vessels at tumor
sites.
Forty - thousand people die every year of breast
cancer because the disease has spread to
other sites in the body.
While chemotherapy prior to surgery can eradicate TNBC in approximately 30 percent of patients, in
other patients the
cancer behaves in a manner resistant to chemotherapy and often spreads or metastasizes to distant
sites in the body, at which point there is no proven cure.
Oral
cancer includes ICD - 10 C00 - C06, C09 - C10 and C12 - C14 (which include the lip, tongue, mouth, oropharynx, piriform sinus, hypopharynx and
other and ill - defined
sites of the lip, oral cavity and pharynx).
The spread of
cancer cells from the initial
site of occurrence (primary
site) to
other secondary tissues is called metastasis, and contributes to poor or limited response of
cancer cells to treatments, which results in death.
These
cancer cells tend to be slow growing, and so the
cancer does not spread to
other sites in the body as quickly.
Of those that had the high - risk signature,
cancer spread to the lungs in 55 %, in spite of chemotherapy treatment, whereas only 10 % of the
others showed
cancer migration to the lungs — and even then, the lungs were not the principal or most aggressive
site, the team reports 28 July in Nature.
TCGA is still worth it, he says, but «the return on the investment [for this
cancer] is less than for
other tumor
sites.»
Metastasis is a life - threatening condition in which
cancer cells break away from the
site where they formed to
other areas of the body.
This is contradictory to the common concept that
cancer cells undergo a series of mutations in the course of tumor growth to acquire the ability to leave the primary
site of the tumor and start migrating to
other parts of the body.
Thoracic Oncology — Lung
cancer, malignant mesothelioma, thymoma and thymic carcinoma, small cell
cancer in
other body
sites, chest sarcomas, pulmonary carcinoid tumors,
other rare thoracic
cancers
Metastasis, the process by which
cancer cells disseminate from their primary
site to
other parts of the body, leads to the death of most
cancer patients.
The South Orange Avenue
site will house teams of health experts including
cancer surgeons, radiation oncologists, specialized nurses, patient navigators, social workers, dieticians, pharmacists and
other support staff, as well as researchers.
Well, the cervical
cancer work, of course, and what we found about
cancers at these
other sites — we participated in studies that showed the etiologic heterogeneity of vulvar and head and neck
cancers.
The Richmond
site plans call for a 2 - million - square - foot facility at the 120 - acre Richmond Field Station that will house more than 800 scientists doing research in bioscience,
cancer, bioenergy and
other research.
Because they can be programmed to travel the body and selectively target
cancer and
other sites of disease, nanometer - scale vehicles called nanocarriers can deliver higher concentrations of drugs to bombard specific areas...
Kiran Turaga, MD, MPH, is a surgical oncologist with a special interest in the treatment of advanced malignancies, including metastatic
cancers (
cancers that have spread beyond their original
site to
other parts of the body).
One of the major parameters was the safety of these agents in the respiratory airways and lung parenchyma, since several of these agents are known to cause adverse effects.23 The main adverse effects observed were cough, transient fever and transient decrease in the respiratory functions after the aerosol administration.8, 19, 20 Moreover; it has been observed that excessive deposition of these agents in one
site of the respiratory system can induce non-specific side effects in the form of pulmonary edema as observed with many
other drugs.16 These side effects were milder when a premedication with bronchodilators and inhaled corticosteroids were administered.8, 19, 20 Until now no long term trial (> 9 months) has been performed since all patients included in previous studies had stage IV non-small cell lung
cancer (NSCLC).
Mucosal melanoma is a rare disease, accounting for only 0.03 % of new
cancer diagnoses, and it is distinct from melanomas that develop at
other sites in the body.
In addition to the risk of second
cancers decades later, radiation to growing bones and organs could impede normal development, and radiation to the brain, a common
site of pediatric
cancers, often resulted in impairments to learning and
other cognitive brain functions.
Melanoma is more likely than
other skin
cancers to spread beyond the initial tumor
site to
other organs, but all the patients had localized disease.
Cancer can often spread to the liver from
other sites such as the breast or lung.
The work, led by researchers at the UNC Lineberger Comprehensive
Cancer Center at the University of North Carolina at Chapel Hill and
other TCGA
sites, not only revamps traditional ideas of how
cancers are diagnosed and treated, but could also have a profound impact on the future landscape of drug development.
The researchers also could not assess how many
cancers developed from the
site of the initial suspicious mammographic finding and how many were missed
cancers from a different location, including the
other breast.