Sentences with phrase «other cell functions»

Work ranges from analysis of the functions of genes identified to cause eye diseases when mutated, to the direct effects of UV - light and other agents associated with the development of eye disease on mitochondrial and other cell functions.

Normally, they open and close very quickly and in sync with other cell functions to make the heart work.

Not exact matches

One day, Reynolds says, a version of InVivo's implant, packed with stem cells or hormones, might help the six million Americans who are chronically paralyzed from SCI and other central nervous system disorders improve their level of functioning.

Essentially the model reproduces the inner workings of all of the proteins within the organism and allows scientists to see everything from how cells interact with each other to the functions of genes in a larger context that had not been previously understood.

For instance, motion pictures of living brain cells taken through a microscope reveal tiny microglial cells that look like spiders and climb the trunks and branches of neurons cleaning up debris and performing who knows what other functions.

But cholesterol is actually an important component of our cell membranes and influences hormone biology, among other functions.

They should function as storage and wallet at the same time for other things which you will need frequently, such as pacifiers, wipes and cell phone at your own convenience.

They found that particular cells in the breast must remain insulin sensitive to develop properly and function in the presence of other hormones of lactation.

In these and other inherited diseases, 10 to 15 percent of the single - base pair mutations that cause the disease create a misplaced, premature «stop» codon in the middle of the gene — causing the machinery of the cell to prematurely halt synthesis of the protein, which destroys its ability to function.

Until recently it has been difficult to study the role of glial cells in controlling appetite or any other brain function, because scientists haven't developed many techniques for silencing or stimulating these cells, as they have for neurons.

Researchers filled in other details about the selective role of LKB1 in regulatory T cells, including that the molecule unexpectedly works through the Wnt signaling pathway to adjust regulatory T cell function.

The findings add to a growing body of evidence that protecting or boosting neurotrophins — the molecules that support the survival and function of nerve cells — may slow the progression of Huntington's disease and other neurodegenerative disorders.

«I was very curious at that point what glial cells would be doing in the hypothalamus, since glial cells have been shown in other brain areas to have an influence on regulation of neuronal function,» she says.

«Since it exhibits various other functions in cell metabolism, potential side effects are still difficult to assess.»

Rossoll says his team's research helps to clarify SMN's role in motor neurons and other cells, and insights into its function could be important for optimizing delivery of the newly available treatment or development of additional treatments.

These cells have improved the mechanical function in every other species in which they have been tested, so we are optimistic they will do so in this model as well,» Murry said.

In the meantime, the MUSC team, led by Yu, will continue their work and try to extend the current findings by investigating how other miRs may be involved in regulating T - and B - cell function during allogeneic BMT.

As it can take weeks to grow human cells into intact differentiated and functional tissues within Organ Chips, such as those that mimic the lung and intestine, and researchers seek to understand how drugs, toxins or other perturbations alter tissue structure and function, the team at the Wyss Institute for Biologically Inspired Engineering led by Donald Ingber has been searching for ways to non-invasively monitor the health and maturity of cells cultured within these microfluidic devices over extended times.

The surrounding neurons that were there all along, however, had sprouted a denser set of connections with other cells, presumably allowing for better transmission of information and recovery of function.

Our brain contains billions of cells, each of which need to communicate between each other in order to function properly.

Researchers still don't know how this range corresponds to their versatile functions, but being more like a string than like a lump with keyholes means that a protein can make many contacts with other molecules to regulate the network of signals that drives the cell.

But little is known about how ionizing radiation affects the extracellular matrix (ECM), a patchwork of proteins and other biomolecules that surrounds cells and plays a vital role in their shape, movement and signaling functions.

RNA, widely known as a cellular messenger that makes proteins and carries out DNA's instructions to other parts of the cell, is now understood to perform sophisticated chemical reactions and is believed to perform an extraordinary number of other functions, at least some of which are unknown.

And according to a third theory, as organisms age they deteriorate and must spend more energy to repair cell damage — to the detriment of other essential physical functions.

In this study, the researchers noted that conventional approaches to modifying organisms to consume novel nutrients constitutively (i.e. with no «off switch») can lead to inefficiencies when the nutrient metabolic pathways are not linked to downstream pathways for stress - responses, cell growth and other functions important for the health of the organism.

Daughter cells grow in length and differ from the others to acquire typical functions that allow the root to transport water and nutrients.

In other patients, mutant CFTR proteins that do transit to the cell surface don't function properly.

«This evidence suggests that the DNA timing mechanism is highly conserved, and it is possible that other time - critical functions related to the cell cycle may be regulated in a similar way.

This question has been challenging to address experimentally because attempts to restore function to lost or mutated genes in cancer cells often trigger excess gene activity, causing other problems in normal cells.

If we introduced stem cells with nice, long telomeres in the first place, we could let them wind down and eventually be lost to apoptosis, senescence, or other sources of damage — and just top our tissues up with more stem cells before enough of those cells were lost to begin to impair tissue function.

Laboratory experiments suggest that RNA could have replicated itself and carried out the other functions required to keep a primitive cell alive.

Others want to deliver working copies of broken genes into retinal cells, restoring their function.

This blood vessel normalization results in an increased barrier function on the one hand — thereby blocking cancer cell dissemination and metastasis - and in enhanced tumor perfusion on the other hand, which increases the response of the tumor to chemotherapy.

Changes to the properties of the lipid bilayer component of the cell membrane can alter the function of proteins embedded in the membrane — proteins that regulate critical functions such as transport of materials in and out of the cell and communication with other cells.

In addition, she and her colleagues think that they will be able to identify other genes that have an important role in hair cell function.

The researchers concluded that using collagen - based membranes in organ - on - a-chip devices enhance the growth, viability and barrier function of human colon cells and that the method likely could be extended to cells from other organs.

Resar says the team plans to continue investigating the function of HMGA1 and SOX9 in intestinal and other cancers as well as their role in stem cells.

These genes are believed to be essential for the normal function of nerve cells, and previous studies have linked these mutations to problems with synaptic function — how neurons communicate with each other.

Aging is associated with the gradual loss of brain cells, sleep disturbances and declining memory function, but how these factors are related to each other has been unclear.

These cells quench the function of T - cells and other immune cells, which participate in the immune response against the mycobacteria.

If we knew what those functions were, then maybe we'd have a better way of manipulating these cells, so I'd be keen on performing some experiments to explore what these other genes do.

Proteins control essentially all biological processes in a cell, and while they may sometimes act alone, proteins most often interact with other proteins to carry out their normal biological functions.

The study published in Cell Metabolism reports a mechanism by which two types of brain cells, neurons and glia, normally support each other's functions.

Monitoring immune cell activity — including phenotyping immune cell subsets, tracking cell proliferation, and measuring cytokine production — can provide insights into the overall status of immune function in patients, particularly those undergoing immunosuppression after transplants, enduring cancer treatment, or suffering from autoimmune disease or other pathologies that affect the immune system.

Colleagues of Ben - Ze «ev had examined the effect of turning off b - catenin on other, unrelated functions within cells.

Insulin sensitivity refers to insulin's ability to efficiently respond to and regulate glucose in the blood, so that our cells can use it for energy and other functions.

Vitamin B12 helps red blood cells and nerves work properly, among other functions.

Every cell in the body uses phosphorylation, the process of adding a chemical tag to control a protein's function and fate, such as when it moves from one part of a cell to another or binds to other proteins.

«What I find most fascinating is that it suggests that viruses can function with a sort of primitive «hive mentality» to ensure efficient use of host cell resources, akin to the way worker bees tell others where to locate the best food sources.»

For a damaged nerve to regain function, its long, signal - transmitting extensions known as axons need to grow and establish new connections to other cells.