Sentences with phrase «other cell states»

Not exact matches

In photovoltaic solar cells, for example, the European Copper Institute (ECI) states that copper is used in cabling, earthing, inverters and transformers, among other things.

These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth in revenues for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount of discount required on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of lowering prices or reducing the number of insured patients; the possibility of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).

«Since the ADD / CVD only impacted Chinese and Taiwanese cells, they could source cells from other markets (e.g. South Korea), do the assembly in the United States, and bypass the ADD / CVD,» Zoco tells pv magazine.

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While study results indicated that combining capsaicin with the chemicals «might promote cancer cell survival,» the report clearly stated that the control group of mice treated only with capsaicin ``... did not induce any skin tumors...» In addition, the study repeatedly cited other research studies in which the anti-cancer properties of capsaicin were solidly demonstrated.

More than 40 states require screening at birth for sickle cell anemia, along with other routine newborn screening tests.

All states require at least some newborn testing, like screening for PKU, sickle cell anemia, and other inherited conditions.

`' While the Arewa youths are enjoying state dinners, Niger Delta youth activists such as Ezekiel Daniel, Alex Odogu, ex-militant leader, Bonny Gawei and several others are in underground detention cells.

Cell phones, smart phones, and other personal electronic devices are free from arbitrary police snooping in California — at least for the time being, thanks to actions taken by the state legislature and Governor Jerry Brown.

Eastern District Assistant United States Attorneys Lara Treinis Gatz and John Durham said in the letter that the strength of the government's case «is overwhelming and consists of dozens of witnesses... fully corroborated by numerous sources of evidence... including telephone call detail records, cell site records, photographs, financial records... and other documentary evidence.»

Bronx State Senator Jeffrey Klein heads the splinter cell, and its other members include Staten Island State Senator Diane Savino, Queens State Senator Tony Avella — now challenging Mayor Bill de Blasio in the Democratic primary — Rockland County State Senator David Carlucci and Syracuse State Senator David Valesky.

According to Raymond Geor, an exercise physiologist at Michigan State University, sled dog muscle cells are well equipped to use this fat because they have a higher mitochondrial density — more cellular power plants — than other animals.

Yet, consumer watchdog groups and others in the state are impatient for the stem cell treatments that they feel they were promised during the Prop. 71 campaign and have misgivings about the amount of money being poured into research in years when California has endured a dire financial crisis.

When the laser is switched off, the water returns to its high - density state, forcing the cell to «suck in» water and any other molecules, including drugs, from its surroundings.

«Most researchers have relied on cell lines to screen the effect of drugs and other treatments including viruses,» said Dr. Cripe, who also is a professor at The Ohio State University College of Medicine.

Automakers have said they're concentrating fuel - cell vehicle sales in California, expanding to other states as more hydrogen fueling stations come available.

This set the stage for a relatively restrictive environment for embryonic (although not adult) stem cell research in the United States relative to some other countries — the National Institutes of Health currently funds between about $ 600 miilion to $ 700 million a year in stem cell research.

They then used next generation sequencing — a state - of - the - art method to rapidly measure gene expression — to sequence and quantify the thousands of genes that are expressed in hair cells, in comparison with other cells in the ear.

In Sacramento, California, tax incentives cut the cost of a solar - cell array by up to 75 percent; yet other sunshine - intensive states, including Florida and Arizona, provide no incentives.

«What David's group can do is grow populations of cells in a very miniaturized state in ways that they can reach out and talk to each other through tiny channels, but yet they stay distinct,» den Boon says.

«Dormant disseminated tumors can be ticking time bombs, but now that we know some of the triggers, it may be possible to develop therapies to ensure that disseminated cancer cells remain in a dormant state, or other therapies that eradicate these cells before they form full - blown metastases.»

Just as a careful watcher can gauge the emotional state of a person by noticing a blush or other visual cues, scientists are becoming adept at discerning the state of a cell with the help of molecular «paints» that highlight more than a thousand cellular features together.

Researchers at Oregon State University and Oregon Health & Science University have created new nanomaterials able to cross cell membranes, establishing a novel platform for the intracellular delivery of molecular drugs and other cargo.

Lengner's group and others had previously shown that these reserve stem cells normally reside in a dormant state and are protected from chemotherapy and radiation.

Without CD24, the cells begin to revert toward a stem like state, and without E-cadherin, cells lose some of the «glue» that binds them to other cells, says Sukumar.

Although no one knows exactly how Wnt works, other studies have suggested that the signals may cause cells around an injury to revert to a state similar to that of stem cells, allowing them to be reprogrammed to grow back the missing part.

«Clearly, estrogen regulates TLR8 and other TLRs in ways that change the threshold of an inflammatory response, and female cells are hard wired to be more sensitive to this change,» said Nicholas Young, PhD, a molecular biologist with Ohio State's department of immunology who worked on the study.

Several other states have stepped up to the plate in the wake of federal restrictions on embryonic stem cell research.

Several states — including California, New York, and Connecticut — are rewriting their utility rules so individuals or companies can sell electricity (from a fuel cell or other private power source) back into the grid.

Among other things, House appropriators would zero out SUNPATH III, a $ 25.5 million program to help develop the manufacturing of photovoltaic solar cells in the United States.

This will be an important approach for studying redox changes in disease states including cancer, neurodegenerative disorders, cardiovascular disease, sickle cell disease and many others which are known to involve oxidative stress.»

Other states are contemplating similar moves, but the United States is well behind other nations in stem cell reseOther states are contemplating similar moves, but the United States is well behind other nations in stem cell resstates are contemplating similar moves, but the United States is well behind other nations in stem cell resStates is well behind other nations in stem cell reseother nations in stem cell research.

Other research in this area has required that cells of one type first be returned to a more generally undifferentiated stem cell state, which can introduce fresh problems.

This 0157: H7 makes the headlines, mainly because it's a problem in the United States, but in the other parts of the world there are strains of E. coli that still make children very sick, and they kill millions of children every year, and they have lots of different ways of invading our cells and manipulating them.

Now, a collaboration between the RIKEN Center for Integrative Medical Science (IMS) and other institutions in Japan and Europe have found that in immune cells, simply blocking a transcription factor that leads to differentiation is sufficient to keep cells in a multipotent stem cell - like state where they can continue to proliferate and can later differentiate into various cell types.

But when you analyze your brain, you will find inside it a set of nerve cells that form a large complex: one that can distinguish among a large repertoire of states in a way that its parts can not; and one that does so maximally, more than any other set of nerve cells, more than the entire body, than any crowd of men, than the world itself.»

A. avenae and other anhydrobiotic plants and animals — organisms that can live without water — produce large amounts (up to 20 % of a cell's mass) of certain sugar molecules that harden into a semisolid state.

Though many other cells in the brain have been identified as playing a role in anxiety, the cells found in this study are the first known to represent the state of anxiety, regardless of the type of environment that provokes the emotion.

Other investigators contributing to the new study include Chaoran Yin, Ting Zhang, Yonggang Zhang, Raj Putatunda, Xiao Xiao, Fang Li, Shen Dai, and Xuebin Qin in the Department of Neuroscience at the Center for Neurovirology and the Comprehensive NeuroAIDS Center, Temple University Lewis Katz School of Medicine; Weidong Xiao in the Department of Microbiology and Immunology, Temple University Lewis Katz School of Medicine; Huaqing Zhao in the Department of Clinical Science, Temple University Lewis Katz School of Medicine; Xiying Qu in the Department of Radiology at the University of Pittsburgh School of Medicine, Pittsburgh; and Xianming Mo in the Laboratory of Stem Cell Biology, State Key Laboratory of Biotherapy, West China Hospital, West China Medical School, Sichuan University, Chengdu, China.

Lipton went on to state, «It will be important to see if HIV / AIDS acts similarly on stem cells for other organs in the human body, as this may impact on the disease process as a whole.»

«If you could induce them to resolve that state — to differentiate into one or the other cell type — they would cease to be tumorigenic.»

Stem cells (be they embryonic cells or adult cells that have been induced back to an embryonic - like state) have an amazing ability to become any other living cell as long as the right genetic and external signals are applied.

So what we think is that probably in many cells in this section, all cells, the chromatin is encountered in a specific state, and in order to render the cell is permissive to reprogramming, you have to overcome these certain epigenetic modifications that block, for example, the binding of Ascl1 to its target chains, or the binding of other transcription factors to its target chains, then this way interfere with the possibility of reprogramming.

Opening the way to accurately profile the chromatin states of in vivo stem cells, lineage progenitors and other scarce cell populations.

Using a unique chemical cocktail of small molecules and other reprogramming factors, Dr. Ding never lets the cells enter the pluripotent state.

That allows the two other genes, Sox2 and Oct3 / 4, to bind more easily to the DNA and turn on genes that return the cell to a pluripotent state.

Specter on Monday introduced a bill that affirmatively states that it is legal for the government to fund human embryonic stem cell research — a bill highly similar to the one introduced in the House in March by Diana DeGette (Democrat, Colorado), with one important extra: Specter's bill states that the government should fund the research «notwithstanding any other provision of law, including [the Dickey - Wicker amendment].»

They discovered that extra chromosome 21 - a genetic state known as trisomy 21 - disturbs a key regulating gene called NRSF or REST, which in turn disturbs the cascade of other genes that control normal development at the embryonic stem cell stage.

Taking advantage of the available temporal resolution with FlyMAD, the team was able to show that activity of one type of neurone correlates with a persistent state of courtship, whereas the other cell type was important for the action of singing.

Senescent cells began their existence skin cells, or as related cells that normally play supporting roles in other organs, but were forced into an abnormal state where they lost the ability to divide and reproduce themselves as a protective response to some danger.