Not exact matches
Advances include development of routes and
surfaces that are more wheelchair and walker friendly; signage that includes Braille text and
other tactile information to describe specific points of ecological interest; and trail «tours» that can be experienced through
cell phones and
other smart devices.
By measuring how the light has changed once it emerges through the
other side of the slide, the researchers can detect and monitor processes occurring on the sensor
surface, such as
cell division.
The immune system depends on molecules called T
cell receptors on the
surface of T
cells to recognize and respond to foreign antigens from virus - infected
cells, tumors and
other threats.
Investigators linked the ability of regulatory T
cells to dampen the Th2 response in part to the ability of LKB1 to restrain expression of the
cell surface receptor PD - 1 and possibly
other receptors.
One key gene encodes the making of a receptor called TREM2, a docking site for molecules on the
surface of microglia and
other innate immune
cells.
Previous studies have found that brown fat can be coaxed into action by activating the β3 - adrenergic receptor, which is expressed on the
surfaces of brown and white fat
cells, as well as on
cells of the urinary bladder and
other tissues.
In research that has implications for diabetes and
other metabolic diseases, an international study based at UT Southwestern Medical Center found that the protein connexin 43 (Cx43) forms
cell - to -
cell communication channels on the
surface of emerging beige fat
cells that amplify the signals from those few nerve fibers.
King hypothesizes that proteins that the single -
celled ancestors of animals used to interact with the extracellular environment — to capture bacterial prey by binding to their
cell surface and to detect chemical signals — were later repurposed to enable
cells to stick to and talk to each
other.
Other researchers have already loaded hollow origami structures with drugs to target specific types of cancer
cells, created DNA «robots» that walk across
surfaces, and mimicked the shape of viruses.
Histamine can also affect
other receptors of the
cell surface than the H1 receptor,» Professor Harvima explains.
Although some cancers — particularly those that are rife with mutations like lung cancer or melanoma — create more tangible targets on the
surface of
cells for the immune system to recognize and attack,
other malignancies such as prostate and pancreatic cancers have proved more intransigent.
These proteins latch onto their receptor on the
surfaces of neighboring
cells and kick - start the production of hundreds of
other antiviral proteins.
Some of the animals received normal T
cells back, and
others got
cells deficient in a
surface molecule that activates regulatory T
cells.
In
other patients, mutant CFTR proteins that do transit to the
cell surface don't function properly.
Still, a few stem
cell therapies have now been approved, such as a treatment available in India that takes stem
cells from the patient's eye in order to regrow the
surface of their cornea, and a US product based on
other people's bone stem
cells.
The increased
surface area of the rippling «leaf» creates three times as many catalytic contact points as
other molybdenum disulfide structures, and the new creation can handle higher temperatures than platinum without sintering and gumming up the
cell.
Some would simply crank their telomerase activity up even further; some would enhance the activity of drug - metabolizing enzymes that degrade the inhibitor; still
others would change their
cell surface proteins in ways that would make it harder for the drug to penetrate into the
cell.
The method, which detects DNA from skin
cells, hair, and
other cells released into the environment, has already been used to track
surface organisms like invasive fish and snakes.
The engineered protein has two ends: one activates T
cells by binding to a
surface molecule called the CD3 receptor, and the
other — based on an antibody called VRC07 — powerfully binds to more than 90 percent of HIV strains.
AFM didn't catch the details of microvilli and
other structures on the
cell surface.
Other teams are trying to find ways of targeting the progenitor
cells that give rise to the
surface cells.
The
other kind is peritubular — that is, located on the
surface of the seminiferous tubules that house sperm
cell precursors.
Nearly doubling the efficiency of a breakthrough photovoltaic
cell they created last year, UCLA researchers have developed a two - layer, see - through solar film that could be placed on windows, sunroofs, smartphone displays and
other surfaces to harvest energy from the sun.
Nevertheless, as Tobias says, it is still ``... a field beset with relatively few facts but many theories... The story of early hominid brains has to be read from carefully dated, well identified, fossilised calvariae, or from endocranial casts formed within them... Such materials confine the Hercule Poirot, who would read «the little grey
cells» of fossil hominids, to statements about the size, shape and
surface impressions... of ancient brains...» The
other major limiting factor at the moment is the lack of suitable fossil skulls for such studies.
The
cells, which can be processed to be transparent or in shades ranging from light green to brown, could be used to make building windows, smartphone screens, car sunroofs and
other surfaces into sources of sustainable energy.
«The NILR1 is the genetic code for a receptor protein that is localized to the
surface of plant
cells and is able to bind and recognize
other molecules,» says Prof. Florian Grundler, chair at the Department of Molecular Phytomedicine at the University of Bonn.
Most resistance genes, in wheat and
other plants, code for protein receptors located inside
cells; the Stb6 gene codes for a receptor protein on the
cell's
surface.
In earlier work, these investigators showed — as numerous
others had done — that the messenger molecule, cyclic - di - GMP (c - di - GMP) promotes biofilm formation when such
surfaces are present, said principal investigator Vincent T. Lee, Associate Professor, Department of
Cell Biology and Molecular Genetics, University of Maryland, College Park.
Solar
cells, 62,120 of them, distributed over the
surface of the wing, soak up the sun's rays, providing up to 32 kilowatts of direct - current electricity to power electric motors, computers, and
other systems on the aircraft.
NASA researchers triggered international headlines in 1996 when they discovered, among
other possible indicators of life, traces of polycyclic aromatic hydrocarbons (multiringed carbon molecules found in living
cells) along
surface fractures in ALH84001.
The
other study published in the American Chemical Society's Applied Materials & Interfaces reported a method for fabricating titanium implants with special
surface topographies which double the chance of
cell viability in early stages.
Like many
other fungi, Baker's yeast has mating receptors, proteins on its
cell surface that detect pheromones released by potential partners.
It targets the CD52 glycoproteins on the
surface of mature immune
cells, or lymphocytes, depleting levels of the aggressive T and B
cells without affecting
other lymphocytes.
Electron microscopy of the inner and outer
surfaces of bacterial
cells gives some clues, and crystallography — a process that involves stacking purified proteins into crystals so that their three - dimensional characteristics can be measured — provides
others.
These molecules function by shuttling broken - down proteins called peptides from inside the
cell to the
surface, where
other immune
cells inspect them to see whether they are invaders.
Traditional methods for sorting
cells rely on fluorescent molecular tags, designed to stick to the
surface proteins present on certain types of
cells but not on
others.
Traditionally,
cell culture in the lab has been done in petri dishes and on
other flat
surfaces.
«Only a subset produces IL - 17A upon skin injury, although the
surface markers on these
cells seem identical to those of
other DETCs,» MacLeod said.
If you imagine the female egg
cell (and later, the fertilized egg) as a spherical planet with its own intrinsic biological geography, then certain characteristics of that
cell — the location of protein molecules or RNA messages or biochemical traits like pH or even the internal connective structures called microtubules — will be more prominent in certain regions, like one hemisphere as opposed to the
other, or near the
surface rather than near the core.
Most
cells in our body bind
other cells by means of integrins, molecules that act as bridges located at the
cell surface.
IBM will be partnering with Tokyo Ohka Kogyo Co., Ltd. — a manufacturer of computer chips, LCD televisions and
other devices that require
surfaces treated with chemicals to develop the
cells; he hopes to bring them to market by 2011.
Blocking a protein found on the
surface of ovarian cancer
cells could prevent or reduce the spread of the disease to
other organs, according to new research at the University of Illinois at Chicago.
On the
other hand, if the
surface's tethers are weak, the
cells will rupture all their tethers and not adhere to the
surface at all, leaving uniformly dark footprints.
For example, Dr. Shiloh said, preventing Mtb from attaching to receptors on the M -
cell surface — such as by vaccinating against a bacterial protein — could block the bacteria's entry, infection, and spread to
other organs.
«First, the
surface of cancer
cells has an affinity for platelets — they stick to each
other.
The
other end, known as the constant region, binds to receptors on the
surface of
cells that can direct the immune system to respond in a variety of ways, all in the hopes of eliminating the target on the variable end of the antibody.
«The tilted - angle standing
surface acoustic waves method has the least disturbance or disruption to the living
cells being separated compared to
other available methods so far,» said Ming Dao, principal research scientist, materials science and engineering, Massachusetts Institute of Technology.
Cancer
cells settle to the bottom of the well, where they selectively bind to the antibodies based on their
surface markers (unlike
other devices, the chip can also trap tiny structures called exosomes produced by cancers
cells).
Some of the candidate drugs were definitely boosting the mutant CFTR to the
cell surface while
others seemed like they could open the door.
Additional experiments, including gene knockdown,
surfaced prohibitin as a likely infection aide; prohibitin is a multi-functional protein found in human
cells and in many
other organisms.