Sentences with phrase «other cells involved»

All of these findings were supplemented with several other experiments that were designed to learn how CHI3L1 interacts with other cells involved in the tissue repair response in both human and mouse lungs.

Not exact matches

«In everyday interactions with significant others, people often assume that momentary distractions by their cell phones are not a big deal,» another researcher involved in the study, Meredith David, said.

Convergence produces software for wireless E-commerce, which basically involves buying and selling by cell phone, pager, or other mobile technology.

These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth in revenues for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount of discount required on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of lowering prices or reducing the number of insured patients; the possibility of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).

One involves a clump of cells that couldn't survive outside the human body, the other involves actual living beings.

Metastasis involves clumps of cancer cells becoming detached and moving through the blood stream or the lymphatic system to other areas, where they become attached to a new site and continue growing.

The increasing use of in - vitro - fertilisation techniques, and the emergence of new possibilities involving human cloning, mixing of human and animal genetic elements, and the use of embryonic stem cells for research, among other things, brought the need for further teaching.

Since in the rest of the world besides ourselves processes of «taking account of» are going on, be it in electrons or atoms or cells, then it is logical to suppose that this subject - object relationship involves subjectivity for these other entities.

So, the other night I saw a strange thing while watching cable (no, tragically, psychedelics were not involved)-- it was an ad for a cell phone that was clearly intended for older people who were scared of cell phones.

Each factor involved in the tumor response — whether it is the speed with which chemotherapeutic drugs reach the tissue or the degree to which cells signal each other to grow — is characterized by a mathematical equation that captures its essence.

But, we must not allow those concerns to block medical advances that may someday be achieved through other kinds of research that involve cloned cells.

He and others have proposed that a group of cells involved in early development called the neural crest are responsible for the suite of traits associated with domestication syndrome.

While doing her Ph.D., Wang came across a defense mechanism in plants involving apoptosis, where «the plant cell is induced to die around the infection site so the pathogen can not be spread to other tissues,» Wang says.

The genes in the network are thought to be involved in how brain cells communicate with each other.

In 2011 researchers found that these waves of electricity cause neurons in the hippocampus, the main brain area involved with memory, to fire backward during sleep, sending an electrical signal from their axons to their own dendrites rather than to other cells.

Some of the other projects involve the development of proton exchange membrane for fuel cell application, a gyroscope based on micro-electromechanical technology and research on innovative engineering materials to fabricate ceramic membranes that can partially oxidize methane to syngas used as feedstock in commercial methanol production.

The relevant patents involve the positioning of differentiated retinal cells in the eye and not the creation of these cells and would potentially be exempt from the ruling; his team wrote its patent this way to distinguish it from other stem - cell - based applications — they felt that describing the placement of cells rather than the creation of the cells was likely to be more novel.

He was able to show that the leucine repeats on c - jun and c - fos «zipped» the proteins together — evidence that C - FOS proteins could interact with other proteins involved in cancerous cell replication.

Other genes activated by the guide RNA encode mitochondrial proteins that help cells regulate their energy metabolism, and trafficking proteins that are involved in packaging and transporting other protOther genes activated by the guide RNA encode mitochondrial proteins that help cells regulate their energy metabolism, and trafficking proteins that are involved in packaging and transporting other protother proteins.

The gene makes a protein that controls the quantities of other proteins a cell produces, and studies in roundworms suggest that the gene is involved in growth and development throughout life.

In addition, they also found a second — and possibly more important — role that they hadn't expected, Maniatis says: IKKε was actively involved in turning on other antiviral genes within a cell.

Such analyses have tied Alzheimer's risk to several genes involved in innate immunity — the body's immediate defenses that indiscriminately attack pathogens and other foreign molecules and cells.

In the meantime, the MUSC team, led by Yu, will continue their work and try to extend the current findings by investigating how other miRs may be involved in regulating T - and B - cell function during allogeneic BMT.

It found that genes associated with depression are involved in brain cell development, and that there was overlap between these genetic regions and those linked to schizophrenia and other mental illnesses.

Another strategy, which Steinman and others were studying, involves a therapy to target dendritic cells inside the body rather than taking them out and personalizing therapy for each patient.

There are now other methods to make stem cells, but those made via SCNT have unique value because they are genetic copies of the living person who donated the skin cells (other methods either use foreign cells or involve genetic reprogramming).

The human version of the cells, called region - selective pluripotent stem cells, or rsPSCs, can also grow inside a mouse, something other human stem cells can't do, says Jun Wu, a research associate involved in the work, published in May in Nature.

The result, published January 5 in Science Immunology, suggests that the protein, a receptor involved in immune cell signaling, plays a role in spontaneous abortions and other human pregnancy complications.

But cellular immunity involves other players — such as macrophages, the network of chemical messengers called cytokines, and so - called natural killer cells — that have received scant attention.

First, it would necessarily involve denying cancerous cells access to some tool that is absolutely indispensable to their survival, so that they couldn't just make up for its loss by tweaking some other gene expression pathway through mutating its other genes.

Now, with new kinds of technologies that are coming up, new types of tissue engineering and, you know, some of the hopes that people have for stem cells and [the] like, it may be interesting to see if there are other ways, alternatives to dealing with really badly damaged hearts that would involve growing a new heart or replacing or repairing the damage d to a badly damaged heart that might make artificial hearts less important in the somewhat more distant future.

What federal oversight should embryonic stem cell research have that other forms of biomedical research, including those involving human subjects, do not already have?

The researchers also want to see what other proteins and mRNAs are involved in the relationship, and why some cancer cell lines they tested did not show the same increased ALKBH5 levels in response to low oxygen levels.

This animation guides us through the immune pathways involved in the disease, from the first signs of self - reactive immune cells to joint damage and other symptoms.This article was reproduced with permission and was first published on January 25, 2016.

The researchers found five different sub-types of HL among the patients studied: 247 cases of the nodular sclerosis (NS) type, in which the tumour nodules are large; 105 of mixed cellularity, where a mixture of different types of inflammatory cells are involved; 58 lymphocyte rich, the sub-type with the best outcome; 68 «others»; and 143 «not otherwise specified» (NOS).

The research suggests that the ADGRE2 subunit interaction plays a key role in the mast cell response to certain physical stimuli, which could have implications for other diseases in which mast cells are involved.

Particularly prominent in the RNA - Seq analysis was the up - regulation of a number of granzymes, a group of proteinases secreted by immune cells that were originally thought to be involved in killing (via apoptosis) virus infected cells or other target cells.

The study involved extracting Ribonucleic acid or RNA — found in the cells of all living organisms — to develop a transcriptome — the gene readouts in a cell — to examine what occurs during the different developmental stages of the cockroach pregnancy and to explore if those changes hold wider applications for other mammals.

Some of the genes involved help regulate the flow of ions in and out of the cells, particularly nerve cells; others code for so - called heat shock proteins that are typically induced during stress.

The research suggests that reducing production of the protein, called myoferlin, affects cancer cells in two primary ways: by changing the activation of many genes involved in metastasis in favor of normal cell behavior, and by altering mechanical properties of cancer cells — including their shape and ability to invade — so they are more likely to remain nested together rather than breaking away to travel to other tissues.

We found 20 genes that distinguished motor neurons that innervate digit muscles from the others, and there's a strange gene code involved in the cells» development.

«Use of induced pluripotent stem cell (iPSC) technology» — which involves taking skin cells from patients and reprogramming them into embryonic - like stem cells capable of turning into other specific cell types relevant for studying a particular disease — «makes it possible to model dementias that affect people later in life,» says senior study author Catherine Verfaillie of KU Leuven.

The team is now working with doctors at Massachusetts General Hospital, who hope to use the new, noninvasive technique to study cells involved in cancer, asthma, and other conditions in which cell properties change as a disease progresses.

Glk1 is a transcription factor, meaning it binds to specific regions of DNA and activates genes involved in cell death and other plant immune responses.

They looked at white blood cells called monocytes, a major cell type involved in rheumatoid arthritis, and found that those cells behaved differently in one group than in the other.

Other diseases, such as the rare lung disease LAM, also involve circulating abnormal cells, Langer says.

«Compared to other ways of trying to develop stem cells to treat blood diseases, this method is safer and quicker, because it does not involve using any artificial substances or any genetic modifications, merely a substance that already exists inside the body,» explains Kenichi Miharada.

In addition to examining the role of mitochondria in other organ and system function, the researchers also plan to search for ways to increase the amount of KLF4 in cells involved in the heart's work.

FosB is a transcription factor in the brain which, together with other molecules, is involved in so - called signal transduction (transmission of stimuli to the cells), that is to say conveys genetic information between the cells and also determines whether certain genes are activated or not.

But he's not sure if the court's reasoning would have weight in cases involving projects other than stem cells.