Like NF - κB, several
other cellular pathways are effected by terpene and plant chemicals.
Not exact matches
Pathways involved in
cellular metabolism typically regulate themselves, meaning that some components of the
pathway control each
other's activities.
The
other study showed how using a combination of drugs at increased potency could prove an effective therapy against glioblastoma by inhibiting the PI3K and MAPK
cellular pathways.
But the finding that all these genetic differences trigger the same
cellular pathway provides hope for
others.
In particular, he is interested in explaining how inflammation in the body alters
cellular pathways, resulting in cancers and
other diseases.
These studies will provide new leads to understand the
cellular pathways that control K2P function in
other organisms.
Numerous studies have demonstrated activity of these agents against a wide variety of cancers, especially cancer stem cell - like subpopulations, by a host of different mechanisms which comprise inhibition of signaling
pathways, of mitochondrial respiration, as well as of
cellular stress responses and
others.
The accumulation of calcium can then regulate the contraction of muscles, trigger the release of neurotransmitters or hormones, modulate intracellular signaling
pathways, and impact several
other calcium - dependent
cellular functions.
The researchers discovered that, when exposed to extra glucose, the cardiomyocytes over-activated the pentose phosphate
pathway — a
cellular process that, among
other things, generates nucleotides, the building blocks of DNA.
Therefore the group studies with sophisticated imaging technology in vitro and ex vivo: i) the molecular mechanism driving the migration of HIV through the intestinal epithelial barrier; ii) the
cellular targets in the mucosa, in specific macrophages and DCs, to identify the possible
pathways to invade the tissue and disseminate to
other organs; iii) the involvement of DCs and their functional properties in mediating adaptive immune responses at mucosal level; and iv) the role of antibodies with different effector functions in changing the
pathways of the virus.
This understanding of the
cellular and molecular mechanism of recovery from acute promyelocytic leukaemia opens prospects for activating this same PML / p53
pathway in
other types of cancers.
In humans and most
other eukaryotes, the RNAi
pathway can reduce
cellular protein production by reducing the proteins» RNA templates.
Some are genetically based, and
others are «damage» based, meaning they involve chemical
pathways within the body which result in damage to
cellular structures and body tissues.