Not exact matches
Currently, Deng's laboratory is conducting additional preclinical studies using the human - derived stem cells from Down syndrome patients and mouse models to determine whether
cellular and behavioral abnormalities can be improved with minocycline
therapy and
other candidate drugs.
The
other study showed how using a combination of drugs at increased potency could prove an effective
therapy against glioblastoma by inhibiting the PI3K and MAPK
cellular pathways.
Basically what was happening when you use a hematopoietic stem cell to correct an inherited metabolic disease is that through engraftment of that cell you are allowing that cell to become the replacement source for the missing enzyme or
other factor - almost like a
cellular form of gene
therapy or, as I call it, «poor man's gene
therapy».
Highly active antiretroviral
therapy (HAART) has been highly successful in decreasing morbidity and mortality of HIV / AIDS, although
other synergistic strategies are required to completely remove any
cellular reservoirs of latent virus.
He has significant experience with respect to transactions related to small molecule pharmaceuticals, biologics,
cellular therapies, gene
therapy, diagnostics and medical devices, both within the United States as well as in
other major markets such as Europe, Asia and South America.