Sentences with phrase «other clinical findings»

«Without the context of a medical history of that patient, plus information from other clinical findings in relation to that patient, risk would be hard to assess,» says a spokesperson for University College London's Cancer Institute.

Researchers used those and other clinical findings to calculate the cumulative burden by tracking the incidence and severity of cardiovascular disease.

Not exact matches

Founded in 2011, Innovent has built a portfolio of 16 potential products for treating cancer, autoimmune disorders and other diseases, and seven of those are in clinical development.

A study published in The Journal of Clinical Endocrinology & Metabolism found that individuals who consume a calorie - restricted diet had lower levels of T3 thyroid hormone, which Healthline lists as a «hormone that helps maintain body temperature, among other functions.»

Appropriate care for the previous generation involves, among other things, what family therapist Murray Bowen has called «differentiation of the self from the family of origin» (see Family Therapy and Clinical Practice [Aronson, 19781) Those who work professionally with families have found that people experiencing marital or other family pain frequently have an unfinished agenda with the prior generation.

I may be slower than others, but I do not find in the literature absolute statements of the clinical factors unanimously agreed to by medical professionals defining PVS.

This is an incredibly difficult question to answer for a variety of reasons, most importantly because over the years our once vaunted «beautiful» style of play has become a shadow of it's former self, only to be replaced by a less than stellar «plug and play» mentality where players play out of position and adjustments / substitutions are rarely forthcoming before the 75th minute... if you look at our current players, very few would make sense in the traditional Wengerian system... at present, we don't have the personnel to move the ball quickly from deep - lying position, efficient one touch midfielders that can make the necessary through balls or the disciplined and pacey forwards to stretch defences into wide positions, without the aid of the backs coming up into the final 3rd, so that we can attack the defensive lanes in the same clinical fashion we did years ago... on this current squad, we have only 1 central defender on staf, Mustafi, who seems to have any prowess in the offensive zone or who can even pass two zones through so that we can advance play quickly out of our own end (I have seen some inklings that suggest Holding might have some offensive qualities but too early to tell)... unfortunately Mustafi has a tendency to get himself in trouble when he gets overly aggressive on the ball... from our backs out wide, we've seen pace from the likes of Bellerin and Gibbs and the spirited albeit offensively stunted play of Monreal, but none of these players possess the skill - set required in the offensive zone for the new Wenger scheme which requires deft touches, timely runs to the baseline and consistent crossing, especially when Giroud was playing and his ratio of scored goals per clear chances was relatively low (better last year though)... obviously I like Bellerin's future prospects, as you can't teach pace, but I do worry that he regressed last season, which was obvious to Wenger because there was no way he would have used Ox as the right side wing - back so often knowing that Barcelona could come calling in the off - season, if he thought otherwise... as for our midfielders, not a single one, minus the more confident Xhaka I watched played for the Swiss national team a couple years ago, who truly makes sense under the traditional Wenger model... Ramsey holds onto the ball too long, gives the ball away cheaply far too often and abandons his defensive responsibilities on a regular basis (doesn't score enough recently to justify): that being said, I've always thought he does possess a little something special, unfortunately he thinks so too... Xhaka is a little too slow to ever boss the midfield and he tends to telegraph his one true strength, his long ball play: although I must admit he did get a bit better during some points in the latter part of last season... it always made me wonder why whenever he played with Coq Wenger always seemed to play Francis in a more advanced role on the pitch... as for Coq, he is way too reckless at the wrong times and has exhibited little offensive prowess yet finds himself in and around the box far too often... let's face it Wenger was ready to throw him in the trash heap when injuries forced him to use Francis and then he had the nerve to act like this was all part of a bigger Wenger constructed plan... he like Ramsey, Xhaka and Elneny don't offer the skills necessary to satisfy the quick transitory nature of our old offensive scheme or the stout defensive mindset needed to protect the defensive zone so that our offensive players can remain aggressive in the final third... on the front end, we have Ozil, a player of immense skill but stunted by his physical demeanor that tends to offend, the fact that he's been played out of position far too many times since arriving and that the players in front of him, minus Sanchez, make little to no sense considering what he has to offer (especially Giroud); just think about the quick counter-attack offence in Real or the space and protection he receives in the German National team's midfield, where teams couldn't afford to focus too heavily on one individual... this player was a passing «specialist» long before he arrived in North London, so only an arrogant or ignorant individual would try to reinvent the wheel and / or not surround such a talent with the necessary components... in regards to Ox, Walcott and Welbeck, although they all possess serious talents I see them in large part as headless chickens who are on the injury table too much, lack the necessary first - touch and / or lack the finishing flair to warrant their inclusion in a regular starting eleven; I would say that, of the 3, Ox showed the most upside once we went to a back 3, but even he became a bit too consumed by his pending contract talks before the season ended and that concerned me a bit... if I had to choose one of those 3 players to stay on it would be Ox due to his potential as a plausible alternative to Bellerin in that wing - back position should we continue to use that formation... in Sanchez, we get one of the most committed skill players we've seen on this squad for some years but that could all change soon, if it hasn't already of course... strangely enough, even he doesn't make sense given the constructs of the original Wenger offensive model because he holds onto the ball too long and he will give the ball up a little too often in the offensive zone... a fact that is largely forgotten due to his infectious energy and the fact that the numbers he has achieved seem to justify the means... finally, and in many ways most crucially, Giroud, there is nothing about this team or the offensive system that Wenger has traditionally employed that would even suggest such a player would make sense as a starter... too slow, too inefficient and way too easily dispossessed... once again, I think he has some special skills and, at times, has showed some world - class qualities but he's lack of mobility is an albatross around the necks of our offence... so when you ask who would be our best starting 11, I don't have a clue because of the 5 or 6 players that truly deserve a place in this side, 1 just arrived, 3 aren't under contract beyond 2018 and the other was just sold to Juve... man, this is theraputic because following this team is like an addiction to heroin without the benefits

The workshop featured presentations from invited speakers and discussions to highlight research findings that advance our understanding of the effects of maternal care services in different types of institutional settings on maternal labor, clinical and other birth procedures, and birth outcomes.

This may especially suit Play Therapists and other Creative Arts Therapists (i.e. IACAT members) who frequently work creatively with clients and will find exploration of their clinical work through Art, Clay Work, Sandplay, Drama and Projection particularly important.

The clinical psychologist who led the research found that kids with pre-psychopathic traits were less engaged with images of others in distress than kids without those traits.

There has been concern raised about a resurgence of vitamin D deficiency and rickets among infants and children, with reports emerging in the United States from Alaska, 1,2 Iowa, 3 Nevada, 4 California, 5 North Carolina, 6 Texas, 7 and mother - infant pairs in Boston, 8 among others.9 The prevalence of vitamin D deficiency in young children also appears to be high in other countries, including England, 10 Greece, 11 and Canada.12, 13 One study from China found a 65.3 % prevalence of vitamin D deficiency among 12 - to 24 - month - olds, but few cases (3.7 %) of radiographic or clinical rickets were noted.14 Previous studies suggest risk factors to be dark skin pigmentation1,3 - 12 and breastfeeding without supplementation.1 - 7, 9,12,13 To date, reports have focused primarily on young infants compared with toddlers.

Although some SIDS experts and policy - makers endorse pacifier use recommendations that are similar to those of the AAP, 272,273 concerns about possible deleterious effects of pacifier use have prevented others from making a recommendation for pacifier use as a risk reduction strategy.274 Although several observational studies275, — , 277 have found a correlation between pacifiers and reduced breastfeeding duration, the results of well - designed randomized clinical trials indicated that pacifiers do not seem to cause shortened breastfeeding duration for term and preterm infants.278, 279 The authors of 1 study reported a small deleterious effect of early pacifier introduction (2 — 5 days after birth) on exclusive breastfeeding at 1 month of age and on overall breastfeeding duration (defined as any breastfeeding), but early pacifier use did not adversely affect exclusive breastfeeding duration.

Statistical analysis showed that the finding was independent of other risk factors contributing to conception, such as age, current smoking, socioeconomic status, bacterial vaginosis, previous deliveries, or clinical periodontal disease.

Regardless of the geographic setting, the goals and challenges of translational research are the same, says Liu: Getting funding and infrastructure support from the government, training young investigators, creating a multidisciplinary community of researchers who can effectively communicate with each other, and finding ways to systematically implement translational research results into clinical practice.

These and other findings from a new study conducted by researchers at Montefiore Health System and Albert Einstein College of Medicine of Yeshiva University, offer the first clinical recommendations for making diagnostic decisions about headaches in pregnant women.

None of the other potential causes, except high velocity motor vehicle collision, was thought to result in these three clinical findings by a large majority of respondents.

He says the findings are also of crucial importance to Genentech and other biotech companies now conducting clinical trials of VEGF therapy.

Although he and others caution about extrapolating the findings to humans, Brune nonetheless calls it «potentially of enormous clinical significance.»

Regulatory issues must be addressed before moving to human studies, Davies said, but the findings published in the August issue of the Journal of Clinical Investigation suggest that it may be possible to manipulate the bacterial residents of the gut — the gut microbiota — to treat obesity and other chronic diseases.

Some said it made them more rigorous, while others said they feel forced to find clinical applications too soon.

Dr. Criner said that despite the clinical trial's finding that the statin drug did not help with COPD flare - ups, information gleaned from this study should help inform other research into the inflammatory nature of COPD.

A study published in the Journal of Clinical Oncology in January of 2015 led by a Sunnybrook Health Sciences Centre researcher found that the likelihood of dying of other causes for a group of men with low - risk prostate cancer in the study was about nine times higher than the risk of dying from the prostate cancer.

Until then, clinicians should be alert to the possibility that preeclampsia may increase the risk of heart defects in fetuses, although more research is needed in other settings to confirm our findings before modification of clinical practice.»

Now a research team at Nottingham has found a way to use clinical MRI to distinguish between MS lesions and other brain white spots which are found in MS.. The study is published in the Multiple Sclerosis Journal.

«One criticism of the PARP drugs is they are not active in patients who have developed resistance to other therapies, but we found veliparib appears to be effective in some platinum - resistant patients with recurrent or persistent disease,» said Robert L. Coleman, MD, lead author of the study and professor and vice chair of clinical research at the University of Texas MD Anderson Cancer Center, Houston.

«We were surprised to find so many similarities between these two diseases, but most striking was that some of these common signatures are shared with other conditions like diabetic retinopathy and age - related macular degeneration,» said William A. Beltran, senior author on the study, an associate professor of ophthalmology in Penn Vet's Department of Clinical Sciences and Advanced Medicine and director of the Division of Experimental Retinal Therapies.

It found that the capacity of clinical and non-clinical staff in hospitals and clinics to deal with incidents such as floods, earthquakes or other natural hazard is severely limited by a high workload and challenging targets which result in high levels of psychological stress.

«Our findings are encouraging, as they suggest that entolimod can be safely combined with other chemotherapeutic, targeted or immunotherapeutic agents as treatment for advanced and very hard - to - treat cancers,» notes Dr. Adjei, who is Senior Vice President of Clinical Research and the Katherine Anne Gioia Chair in Cancer Medicine at Roswell Park.

The immunotherapy drug pembrolizumab — already FDA - approved for other forms of cancer - has been found to be effective in patients with metastatic triple negative breast cancer, according to an international clinical trial led by NYU Langone's Perlmutter Cancer Center.

In 2012, they reported results of a clinical trial that found significant reduction in the size of heart attack - caused scars in patients who underwent the experimental stem cell procedure, compared to others who did not.

The other finding was that these metabolite changes persisted even after the clinical scores for concussion had returned to normal and the athletes were cleared to return to play.

While researchers found that playing strategy games better engaged memory and cognitive control brain regions, making them better suited for improving memory tasks, they hypothesize that action games that stimulate the limbic area and elicit more emotional arousal might be beneficial for other clinical populations like patients with mood disorders.

White and colleagues will work with other collaborators at the Cancer Institute to develop early - phase patient clinical trials based on the findings from this study in the near future.

Hooker notes that these and other study findings could have important clinical implications.

The USPSTF also found inadequate evidence on the effectiveness of targeted screening in persons who are at increased risk for celiac disease (e.g., persons with family history or other risk factors), or on the effectiveness of treatment of screen - detected, asymptomatic celiac disease to improve morbidity, mortality, or quality of life compared with no treatment or treatment initiated after clinical diagnosis.

Although this study is limited by the lack of data on the effects of clinical interventions and neonatal resuscitation efforts that may have been performed at the time of birth, these findings suggest that early detection of perinatal asphyxia is particularly relevant among infants of overweight and obese women although more studies are necessary to confirm these results in other populations.

Research conducted by Bianco and other Rush colleagues published Oct. 6 in the Journal of Clinical Endocrinology and Metabolism found that individuals on levothyroxine who had normal TSH levels were significantly more likely to be taking antidepressants than peers with normal thyroid function.

Crook and his colleagues have already obtained what they describe as «two positive clinical findings» in their attempts to treat AAMI, one with ondansetron and the other with an amino - acid derivative called phosphatidylserine.

«What we found early on was not all mice will mate with each other,» says clinical psychologist Melissa Farmer, who led the study while earning her Ph.D. at McGill University in Montreal, Canada.

The therapy was found to have an acceptable safety profile in all patients, with no clinical or laboratory signs of systemic cytokine release syndrome, a potentially serious toxicity that has been observed in other CAR trials.

The Endocrine Society's Clinical Practice Guidelines on testosterone therapy in adult men recommend prescribing testosterone only to men who have unequivocally low levels of the hormone and decreased libido, erectile dysfunction or other symptoms of hypogonadism, a condition that results from low testosterone, and can be found online at: http://www.endocrine.org/~/media/endosociety/Files/Publications/Clinical%20Practice%20Guidelines/FINAL-Androgens-in-Men-Standalone.pdf

The report, Understanding Psychosis and Schizophrenia: Why people sometimes hear voices, believe things that others find strange or appear out of touch with reality, and what can help, has been written by a group of eminent clinical psychologists drawn from eight universities and six NHS trusts, together with people who have themselves experienced psychosis.

The investigators carried out the same type of analysis with an additional group of 559 patients at three other clinical sites in the United States and found similar results for the association between the genotype and the type of PD symptoms.

They then soaked tiny collagen sponges (which are made from the same protein found in dentin) in various drugs known to stimulate Wnt signaling, including tideglusib, a compound that has been investigated in clinical trials for its potential to treat Alzheimer's and other neurological disorders.

Miller says the response in this study, published in the Journal of Clinical Lipidology, may confirm other research findings about polyunsaturated fats: «Recent data suggest that PUFA (but not MUFA) activates signaling in the brain to reduce appetite, so this may be one reason for the bigger weight drop between the groups.»

Before now, researchers wanting to find out whether disease genes could be targeted with drugs had to search piecemeal through scientific literature, clinical trials databases or other sources of information, some of which were not publicly available or easily searchable.

Some DIMET students» projects take a disease - driven approach, whereas others start with a basic finding and aim to develop clinical applications.

Brose says the results of this study can have an immediate impact in clinical care, and several other studies are ongoing to find new uses for lenvatinib in other types of thyroid cancer.

«Unfortunately, our colleague passed away before this could reach a clinical treatment, but she was happy that even if it couldn't help her, this finding might be able to help other patients in the future,» Johnson says.

The commission is forming a fact - finding team to investigate the unethical experiments, and it will ask an international task force to review whether U.S. rules for clinical trials in other countries are properly protecting human subjects today, Gutmann says.