The Brain and Spinal Tumor Program at the Kimmel Cancer Center is a member of the Adult Brain Tumor Consortium (ABTC), a group of 16 medical centers dedicated to improving treatments for adults with malignant brain tumors by initiating early phase clinical trials and collaborations with researchers and
other clinical trials groups.
Not exact matches
A couple of people talked about
clinical trials (those that I talked about above), and Melissa (FAAN Teen Advisory
Group member) talked about living with Multiple Food Allergies and
other Auto - Immune Disorders.
Others have speculated that, by being involved in a
clinical trial, patients in both arms of the
trial received better care than they would otherwise have done, obfuscating any differences between the
groups.
Another problem is that modeling studies, like this one, are inherently less powerful than
other kinds of medical research: randomized
clinical trials, the gold standard in medical research, in which patients are randomly assigned different treatments or no treatment; case - control studies, which compare patients who have a condition with those who do not; or cohort studies, which determine the risk of contracting a disease by studying a
group of people with similar demographics.
Wyss - Coray, whose
group did most of the mouse studies that inspired the
clinical trial, now plans to conduct a second, larger
trial using plasma from which many proteins and
other molecules have been removed.
The future challenges of this line of research, started through an undergraduate degree final project by Carlos Aguado in the Grupo de Computación Evolutiva y Redes Neuronales (EVANNAI - Evolutionary Computation and Neural Networks
Group) at UC3M, include carrying out
clinical trials using this technology, in addition to developing programs that help rehabilitate the
other four movement of the shoulder: flexing, extension, internal rotation and external rotation.
The phase 2 randomized
clinical trial was conducted by the Eastern Cooperative Oncology
Group, enrolling 245 patients with stage 3 or stage 4 metastatic melanoma who had been treated with
other drugs.
To confirm these results, the next step will be to establish a
clinical trial with patients suffering motor skills disorders due to a stroke and divide them into two
groups: one of them undergoing physiotherapy treatment and the
other with complementary cognitive training.
The study, published in the July issue of the journal Epidemiology, offers benefits over typically used randomized
clinical trials, as such studies are often too small to identify rare side effects or may be performed in a
group of patients who do not take
other types of medications or have
other conditions that could skew the drug's effect in a broader
group following approval.
In a mechanism that Tan hopes will become common, his
group will now hand off this rational combination to
other researchers at the CU Cancer Center and elsewhere who will move the drugs toward a human
clinical trial.
The
group hopes to examine the effect in
clinical trials in the future, and plans to look at the function of the
other six genes their study identified.
«The magnitude of the reduction in thickening of the carotid artery in the treatment
group, relative to the control
group, is similar to what has been observed in
other clinical trials in high risk populations.
For more information regarding Bristol - Myers Squibb
Clinical Trial participation, please visit www.BMSStudyConnect.com Inclusion Criteria: • Early stage IB - IIIA, operable non-small cell lung cancer, confirmed in tissue • Lung function capacity capable of tolerating the proposed lung surgery • Eastern Cooperative Oncology
Group (ECOG) Performance Status of 0 - 1 • Available tissue of primary lung tumor Exclusion Criteria: • Presence of locally advanced, inoperable or metastatic disease • Participants with active, known or suspected autoimmune disease • Prior treatment with any drug that targets T cell co-stimulations pathways (such as checkpoint inhibitors)
Other protocol defined inclusion / exclusion criteria could apply
This project is supported by the Patient Advisory
Group of the International Coordinating Committee for SMA
Clinical Trials which includes: Families of SMA, Fight SMA, Muscular Dystrophy Association, SMA Foundation, and
other SMA advocacy
groups.
Long supported by grants from the National Institutes of Health, National Cancer Institute and
other philanthropic entities, Cole is an active
clinical researcher having developed pediatric cancer
clinical trial protocols in conjunction with the national cooperative organization Children's Oncology
Group and
other collaborators.
Manson and a
group of
other researchers are about to launch a large - scale
clinical trial of the polyphenols — those bioactive compounds — in the cocoa bean.