Sentences with phrase «other clinical uses»

Dr. Vox suspects that if the Nexstim device proves effective, there will be other clinical uses down the line.

Not exact matches

«We're helping [companies] use Ontario's academic and clinical infrastructure to build an incredible dossier or package of evidence that they can now use to walk into any other major player,» says Khayat.

These risks and uncertainties include, among others: the unfavorable outcome of litigation, including so - called «Paragraph IV» litigation and other patent litigation, related to any of our products or products using our proprietary technologies, which may lead to competition from generic drug manufacturers; data from clinical trials may be interpreted by the FDA in different ways than we interpret it; the FDA may not agree with our regulatory approval strategies or components of our filings for our products, including our clinical trial designs, conduct and methodologies and, for ALKS 5461, evidence of efficacy and adequacy of bridging to buprenorphine; clinical development activities may not be completed on time or at all; the results of our clinical development activities may not be positive, or predictive of real - world results or of results in subsequent clinical trials; regulatory submissions may not occur or be submitted in a timely manner; the company and its licensees may not be able to continue to successfully commercialize their products; there may be a reduction in payment rate or reimbursement for the company's products or an increase in the company's financial obligations to governmental payers; the FDA or regulatory authorities outside the U.S. may make adverse decisions regarding the company's products; the company's products may prove difficult to manufacture, be precluded from commercialization by the proprietary rights of third parties, or have unintended side effects, adverse reactions or incidents of misuse; and those risks and uncertainties described under the heading «Risk Factors» in the company's most recent Annual Report on Form 10 - K and in subsequent filings made by the company with the U.S. Securities and Exchange Commission («SEC»), which are available on the SEC's website at www.sec.gov.

In recent years, Levine and others have used clinical studies to prove that even in healthy people, a chair - based lifestyle sets up the physiological conditions for the onset of Type 2 diabetes, cardiovascular disease, obesity — and ultimately, shorter lifespans.

Sun Life will also conduct periodic reviews of the growing body of clinical research supporting the use of medical cannabis for other conditions, and update its criteria if necessary, the company said in a document updating their client base of 22,300 plan sponsors.

M.A.P.S. plans to spin off sales to a for - profit benefit corporation, which would then funnel the money back into clinical research on the use of MDMA with other disorders.

And the San Francisco Chronicle reports that over 100 clinical trials listed on the ClinicalTrials.gov website feature Fitbit trackers in addition to those trials using the Apple Watch, Jawbone, Garmin, Pebble and other devices.

But topping the list is Vertex (VRTX), which has a veritable plethora of HCV drugs in late - stage clinical trials, which are used either alone, or in combination with other drugs.

Judd Marmor and others have used both clinical and other data to show that male homosexuals as a group are no less mentally healthy, by the usual criteria, than heterosexuals — except insofar as blanket discriminatory social attitudes render them so.

This is an incredibly difficult question to answer for a variety of reasons, most importantly because over the years our once vaunted «beautiful» style of play has become a shadow of it's former self, only to be replaced by a less than stellar «plug and play» mentality where players play out of position and adjustments / substitutions are rarely forthcoming before the 75th minute... if you look at our current players, very few would make sense in the traditional Wengerian system... at present, we don't have the personnel to move the ball quickly from deep - lying position, efficient one touch midfielders that can make the necessary through balls or the disciplined and pacey forwards to stretch defences into wide positions, without the aid of the backs coming up into the final 3rd, so that we can attack the defensive lanes in the same clinical fashion we did years ago... on this current squad, we have only 1 central defender on staf, Mustafi, who seems to have any prowess in the offensive zone or who can even pass two zones through so that we can advance play quickly out of our own end (I have seen some inklings that suggest Holding might have some offensive qualities but too early to tell)... unfortunately Mustafi has a tendency to get himself in trouble when he gets overly aggressive on the ball... from our backs out wide, we've seen pace from the likes of Bellerin and Gibbs and the spirited albeit offensively stunted play of Monreal, but none of these players possess the skill - set required in the offensive zone for the new Wenger scheme which requires deft touches, timely runs to the baseline and consistent crossing, especially when Giroud was playing and his ratio of scored goals per clear chances was relatively low (better last year though)... obviously I like Bellerin's future prospects, as you can't teach pace, but I do worry that he regressed last season, which was obvious to Wenger because there was no way he would have used Ox as the right side wing - back so often knowing that Barcelona could come calling in the off - season, if he thought otherwise... as for our midfielders, not a single one, minus the more confident Xhaka I watched played for the Swiss national team a couple years ago, who truly makes sense under the traditional Wenger model... Ramsey holds onto the ball too long, gives the ball away cheaply far too often and abandons his defensive responsibilities on a regular basis (doesn't score enough recently to justify): that being said, I've always thought he does possess a little something special, unfortunately he thinks so too... Xhaka is a little too slow to ever boss the midfield and he tends to telegraph his one true strength, his long ball play: although I must admit he did get a bit better during some points in the latter part of last season... it always made me wonder why whenever he played with Coq Wenger always seemed to play Francis in a more advanced role on the pitch... as for Coq, he is way too reckless at the wrong times and has exhibited little offensive prowess yet finds himself in and around the box far too often... let's face it Wenger was ready to throw him in the trash heap when injuries forced him to use Francis and then he had the nerve to act like this was all part of a bigger Wenger constructed plan... he like Ramsey, Xhaka and Elneny don't offer the skills necessary to satisfy the quick transitory nature of our old offensive scheme or the stout defensive mindset needed to protect the defensive zone so that our offensive players can remain aggressive in the final third... on the front end, we have Ozil, a player of immense skill but stunted by his physical demeanor that tends to offend, the fact that he's been played out of position far too many times since arriving and that the players in front of him, minus Sanchez, make little to no sense considering what he has to offer (especially Giroud); just think about the quick counter-attack offence in Real or the space and protection he receives in the German National team's midfield, where teams couldn't afford to focus too heavily on one individual... this player was a passing «specialist» long before he arrived in North London, so only an arrogant or ignorant individual would try to reinvent the wheel and / or not surround such a talent with the necessary components... in regards to Ox, Walcott and Welbeck, although they all possess serious talents I see them in large part as headless chickens who are on the injury table too much, lack the necessary first - touch and / or lack the finishing flair to warrant their inclusion in a regular starting eleven; I would say that, of the 3, Ox showed the most upside once we went to a back 3, but even he became a bit too consumed by his pending contract talks before the season ended and that concerned me a bit... if I had to choose one of those 3 players to stay on it would be Ox due to his potential as a plausible alternative to Bellerin in that wing - back position should we continue to use that formation... in Sanchez, we get one of the most committed skill players we've seen on this squad for some years but that could all change soon, if it hasn't already of course... strangely enough, even he doesn't make sense given the constructs of the original Wenger offensive model because he holds onto the ball too long and he will give the ball up a little too often in the offensive zone... a fact that is largely forgotten due to his infectious energy and the fact that the numbers he has achieved seem to justify the means... finally, and in many ways most crucially, Giroud, there is nothing about this team or the offensive system that Wenger has traditionally employed that would even suggest such a player would make sense as a starter... too slow, too inefficient and way too easily dispossessed... once again, I think he has some special skills and, at times, has showed some world - class qualities but he's lack of mobility is an albatross around the necks of our offence... so when you ask who would be our best starting 11, I don't have a clue because of the 5 or 6 players that truly deserve a place in this side, 1 just arrived, 3 aren't under contract beyond 2018 and the other was just sold to Juve... man, this is theraputic because following this team is like an addiction to heroin without the benefits

It does not measure other critical brain functions that can be adversely affected by head trauma, such as balance and vision, which is why expert groups [1] recommend a «multifaceted approach to concussion management that emphasizes the use of objective assessment tools aimed at capturing the spectrum of clinical signs and symptoms, cognitive dysfunction, and physical deficits... that are more sensitive to the injury than using any one component alone.»

Current research and the clinical experience of many health care professionals (including me) point to the fact that there are effective strategies for fighting Plagiocephaly and other forms of head flattening without using a helmet.

The other consultants were clinical in resolution, whereas Jada and Eden used a personalized approach.

The IVF refund plan states that if patients do not achieve a live birth after the transfer of all of the embryos resulting from their cycles, 100 % of clinical fees will be refunded back to the patients to use in pursuing other family - building measures such as donor egg or adoption.

Cord blood stem cells can be used to treat dozens of diseases and are being tested in FDA - regulated clinical trials to help people with autism, brain injury, and other conditions.

Although some SIDS experts and policy - makers endorse pacifier use recommendations that are similar to those of the AAP, 272,273 concerns about possible deleterious effects of pacifier use have prevented others from making a recommendation for pacifier use as a risk reduction strategy.274 Although several observational studies275, — , 277 have found a correlation between pacifiers and reduced breastfeeding duration, the results of well - designed randomized clinical trials indicated that pacifiers do not seem to cause shortened breastfeeding duration for term and preterm infants.278, 279 The authors of 1 study reported a small deleterious effect of early pacifier introduction (2 — 5 days after birth) on exclusive breastfeeding at 1 month of age and on overall breastfeeding duration (defined as any breastfeeding), but early pacifier use did not adversely affect exclusive breastfeeding duration.

It states that Patient Rescue will use data streams from hospitals to build other tools, in addition to Streams, that could carry out real - time analysis of clinical data and support diagnostic decisions.

On the other hand, it makes little sense to spend 3 to 5 years in full - time clinical training as a resident if you don't intend to use it — and don't forget that board certifications require regular renewal.

Educational programs use many related terms, including bioinformatics, biomedical informatics, medical informatics, computational biology, clinical informatics, and others.

Now a University of Colorado Cancer Center study published online ahead of print in the journal Oncogene offers compelling evidence explaining this failure and offering a possible strategy for the use of retinoic acid or other retinoids against some breast cancers: Because early clinical trials are often offered to patients who have already tried other more established therapies, breast cancer cells may have been pushed past an important tipping point that offers retinoic acid resistance.

Placebos are used to help accurately measure clinical responses / outcomes when studying the effects of medications, therapies, and other treatments.

Critical factors to achieve a higher level of information sharing include: a) the development and adoption of global data interchange standards that are harmonized between health care and clinical trials; b) the use of technology that is more acceptable to users; c) clarification of and adherence to regulatory requirements for health care and clinical trials; d) implementation of new technologies that are being employed by other industries to facilitate data interchange, specifically the use of the eXtensible Markup Language or XML.

«The work will have direct implications for designing clinical trials using oncolytic viruses, not only for brain tumors, but for other solid tumors.»

Wyss - Coray, whose group did most of the mouse studies that inspired the clinical trial, now plans to conduct a second, larger trial using plasma from which many proteins and other molecules have been removed.

«STS public reporting uses detailed clinical registry data and outcomes that have been risk adjusted, meaning that the results take into account the condition of the patient at the time of surgery and whether or not there were other health problems, such as diabetes.»

Now a research team at Nottingham has found a way to use clinical MRI to distinguish between MS lesions and other brain white spots which are found in MS.. The study is published in the Multiple Sclerosis Journal.

Although further work would be needed to validate the results in humans, the study suggests that a simple blood test along with other clinical indicators could potentially be used to diagnose the disease, the researchers say.

The future challenges of this line of research, started through an undergraduate degree final project by Carlos Aguado in the Grupo de Computación Evolutiva y Redes Neuronales (EVANNAI - Evolutionary Computation and Neural Networks Group) at UC3M, include carrying out clinical trials using this technology, in addition to developing programs that help rehabilitate the other four movement of the shoulder: flexing, extension, internal rotation and external rotation.

Meanwhile, his research teams are moving several other novel therapies toward clinical trials, each of which has potential for use in the synergistic model of cancer treatment that Black believes will offer the best hope for his patients.

The 207 patients enrolled in the clinical trial, known as POSITRON, either did not respond to interferon, could not tolerate it or were unwilling to use it, despite the fact that there were no other treatment options available to them.

And while their study was performed in mice, the drug used has already been tested in clinical trials to treat other, unrelated conditions.

The upshot of this and other experiments conducted by Bogyo's team is that using ebselen to disable a toxin in C. difficile was enough to significantly reduce the clinical symptoms of the infection and block the persistent gut damage in mice.

«We hope that this method will be developed into a clinical tool for club physicians and others in sports medicine, and is used as a basis for the decision on how long the player should rest after a blow to the head,» says Henrik Zetterberg.

AAV viral particles are in clinical trials for other purposes, making the researchers optimistic that this CRISPR delivery method could be used in humans, although more studies are needed.

The proposed clinical trial, in which researchers would use CRISPR to engineer immune cells to fight cancer, won approval from the Recombinant DNA Advisory Committee (RAC) at the U.S. National Institutes of Health, a panel that has traditionally vetted the safety and ethics of gene therapy trials funded by the U.S. government and others.

Long - term use of mifepristone has been studied in clinical trials for other tumors, with minimal adverse effects reported after years of usage.

Gene editing has begun to be tested in clinical trials, using CRISPR - Cas9 and other technologies to directly edit DNA inside people's cells, and multiple trials are recruiting or in the planning stages.

Our team is also looking into how mindfulness might help people with other substance use problems,» said co-author Shirley Serfaty (UCL Clinical, Educational and Health Psychology).

A drug used for decades to treat high blood pressure and other conditions has shown promise in a small clinical trial for autism.

Researchers used those and other clinical findings to calculate the cumulative burden by tracking the incidence and severity of cardiovascular disease.

The MIT researchers have started a company to begin a larger clinical study for validating this approach, and they plan to investigate the possibility of using this technology for other types of cancer.

Individuals who have had mild or transient psychotic symptoms (such as unusual thoughts, suspiciousness, perceptual disturbances) without using substances such as marijuana or alcohol and have a family history of psychosis or other risk factors are considered at clinical high risk for psychotic disorder.

This has previously happened in other fields of health with an automated interpretation of results from an electrocardiogram being routinely used in clinical practice as a decision support system.

For doctors, a practical approach might include screening all adults who have not been screened previously, and using their clinical judgment to consider a patient's risk factors, other health conditions and life events to determine if additional screening is warranted, the task force said.

The study, published in the July issue of the journal Epidemiology, offers benefits over typically used randomized clinical trials, as such studies are often too small to identify rare side effects or may be performed in a group of patients who do not take other types of medications or have other conditions that could skew the drug's effect in a broader group following approval.

The assay was implemented in five countries and tested using a large number of clinical samples from travelers and patients living in areas with a high level of exposure to Zika virus and other flaviviruses.

Vaccine developers are trying to improve vaccines for transplant recipients and other people with a weak immune system, and the samples used in this study came from a clinical trial of different versions of a flu vaccine in patients on immune - suppressive drugs.

«We used clinical microbiology tests to determine whether the molecules had promising activity against Cryptococcus both alone and in combination with other antifungal drugs such as fluconazole.

«Given the continued high prevalence of multivitamin use in the US, it remains critical for us to understand its role on nutritional status and other long - term health outcomes through clinical trials such as PHS II and other new research initiatives.»

Brose says the results of this study can have an immediate impact in clinical care, and several other studies are ongoing to find new uses for lenvatinib in other types of thyroid cancer.