Sentences with phrase «other codons»

In separate experiments, they picked 13 other codons and substituted them for alternatives with the same function across 42 different E. coli genes.

Not exact matches

In these and other inherited diseases, 10 to 15 percent of the single - base pair mutations that cause the disease create a misplaced, premature «stop» codon in the middle of the gene — causing the machinery of the cell to prematurely halt synthesis of the protein, which destroys its ability to function.

To ensure novel genes can not be translated if they get passed on to other organisms, the team would have to go a step further and reassign the freed - up codons so a different amino acid to normal is added to a protein when they occur.

The ribosome, in other words, reads the codons, converts them to amino acids and stitches the amino acids together to form a long chain.

Recently, we and others identified a recurrent somatic activating mutation in the JAK2 tyrosine kinase in polycythemia vera (PV), essential thrombocythemia (ET), and myeloid metaplasia with myelofibrosis (MMM).9 - 13 This mutation results in a valine to phenylalanine substitution at codon 617 within the Jak homology domain 2 (JH2) pseudokinase domain of Janus kinase 2 (JAK2).