We are also investigating targeting the normal source of HB - EGF, inflammatory cells, to determine whether HB - EGF alone or in concert with
other cytokines produced by inflammatory cells is necessary for tumor formation.
Not exact matches
Infectious organisms trip specialized immune cells in the body and cause them to pump out proteins called
cytokines, which
produce inflammation and
other hallmarks of infection, such as chills and fever.
It also interferes with CD8 T cells ability to
produce cytokines, chemical messengers that recruit
other arms of the immune system.
Recent work has revealed that ILCs and T cells mirror each
other in their subclasses, which are defined by the kinds of
cytokines they
produce.
The cells
produce chemicals, called
cytokines, which then stimulate
other immune system cells.
NFκB acts as a master switch for the upregulation of inflammatory
cytokines, adhesion molecules and
other inflammatory gene products
produced in response to inflammatory stimuli.
If the muscles are not functioning properly or are hypertonic / spastic they are actually
producing a host of negative byproducts directly from the muscles themselves as well as through crosstalk to
other endocrine tissues via mechanisms related to
cytokine / myokine function.