Sentences with phrase «other epigenetic modifications»

Toward the end of his postdoc, as a Helen Hay Whitney Foundation fellow, Dr. Lomvardas started working on DNA methylation and other epigenetic modifications of olfactory receptors.

Not exact matches

«From other studies ***** we know that epigenetic modifications of the DPP4 gene, which are associated with an increased production of the enzyme, have a negative impact on the liver metabolism already in young mice, long before fatty liver disease emerges,» says Baumeier.

The Max Planck researchers found that H3K27me3 modifications labeling chromatin DNA in the mother's egg cells were still present in the embryo after fertilization, even though other epigenetic marks are erased.

What's more, the researchers hope to be able to add other types of «omics data such as RNA sequencing, epigenetic information, and histone modifications.

So what we think is that probably in many cells in this section, all cells, the chromatin is encountered in a specific state, and in order to render the cell is permissive to reprogramming, you have to overcome these certain epigenetic modifications that block, for example, the binding of Ascl1 to its target chains, or the binding of other transcription factors to its target chains, then this way interfere with the possibility of reprogramming.

Meanwhile, two other drugs that alter unwanted epigenetic modifications treat cutaneous T - cell lymphoma.

Drug developers, meanwhile, are exploring compounds that may be capable of thwarting epigenetic modifications that cause key genes to become under - or overactive, thereby promoting cancer and other diseases.