The random BAC fingerprinting technique has rapidly become the method of choice for mapping and sequencing the comparatively large genomes of
other eukaryotic organisms, including humans.
The team's work highlights this by presenting a comprehensive view of genome evolution on many different levels (e.g., differences in ploidy, aneuploidy, genetic variants, hybridization, and introgressions) that is difficult to obtain at the same scale and accuracy for
other eukaryotic organisms.
Comparisons of the cytoskeleton and endocytic trafficking systems with those of humans and
other eukaryotic organisms reveal major differences.
Other eukaryotic organelles may have also evolved through endosymbiosis; it has been proposed that cilia, flagella, centrioles, and microtubules may have originated from a symbiosis between a Spirochaete bacterium and an early eukaryotic cell, but this is not yet broadly accepted among biologists.
Our findings show that sex can generate phenotypic and genotypic diversity de novo in the pathogenic yeast C. neoformans with implications for
other eukaryotic microbes and pathogens, including other fungi and parasites that are common pathogens of humans.
This and
other eukaryotic mysteries may resolve more easily as geneticists refine a technique for deciphering DNA from one individual cell.
After a prolonged legal battle, USPTO in February ruled that it wasn't obvious that UC's discovery would work in human and
other eukaryotic cells, giving the Broad a distinct patent advantage.
The vaccine triggers a mechanism known as RNA interference, which is an innate defence mechanism of plants, animals and
other eukaryotic organisms against pathogens.
Not exact matches
AS A species made up of
eukaryotic cells complete with mitochondria, nuclei and
other complex structures, it's easy for us Homo sapiens to look down on the far simpler prokaryotes, the cells of which lack such structures.
Surprises include the discovery of about 20
eukaryotic genes;
other bacteria that have been sequenced have had few, if any, such genes.
Other features in
eukaryotic cells — for instance, the cytoskeleton — may also be of bacterial descent, but so far the molecular record has not yielded unambiguous clues as to their origin.
There is an active dispute as to whether some of the archaebacteria are more closely related to the
eukaryotic nucleocytoplasm than are
others (proponents of the differing views are James Lake of the University of California at Los Angeles and Carl Woese of the University of Illinois at Urbana - Champaign).
In fact, there's reason to believe that all of the properties of cell biology that made complex life possible in the next geologic era were put in place here: cytoskeletons that allow
eukaryotic cells to change shape, and cell polarity that allows cells to send a molecular message to one side of the cell but not the
other, and to interact with nearby cells.
The genome of the archaeon known as Lokiarchaeum («Loki» for short) contains more «
eukaryotic signature proteins» (ESPs) than any
other prokaryote.
The EBP would focus on the natural world, providing a better understanding of biodiversity by first sequencing in great detail the DNA of a member of each
eukaryotic family (about 9000 in all) and eventually generating coarser genomes for the
other eukaryotes.
In previous studies, the same group along with
others had demonstrated that microRNAs (miRNAs) produced by
eukaryotic cells and viruses are present in human blood in highly stable, cell - free forms and these so called circulating miRNAs can serve as non-invasive biomarkers for the early diagnosis of various diseases, including viral diseases.
In last week's filing, attorneys for the Broad Institute asked patent officials to remove two of its issued patents that focus on saCas9 from the original case, as well as two
other patents (and a few affiliated claims in
other patents) that describe techniques for enabling the CRISPR - Cas9 construct to target the nucleus of a
eukaryotic cell.
The
others: our biased perspective of
eukaryotic genomes.
However, even though the Lokiarchaea are relatively complex compared with
other known archaea, they lack the large genome and energy - producing mitochondria of true
eukaryotic cells.
(All multi-cell organisms are made of
eukaryotic cells; the
other type of cell, prokaryotic, is found in single - cell organisms.)
Most
eukaryotic cells also contain
other membrane - bound organelles such as mitochondria, chloroplasts and the Golgi apparatus.
This revealed a convergence in the architecture of bacterial and
eukaryotic membranes and implicated the biosynthetic pathways of hopanoids and
other order - modulating lipids as potential targets to fight pathogenic multidrug resistance.
To enable such a system in plants, the re-designed receptors need to be targeted extracellularly and we need to address
eukaryotic processes that are not fully understood, such as transmembrane signaling, signal - dependent nuclear translocation, and
other signaling complexities.
With all of the
other recent findings, I predict that this is the norm in all
eukaryotic cell genetic machinery.
Kopp et al. (2007) and Schumann et al. (2008) found that a clay layer deposited during the PETM in the Salisbury Embayment (which stretches from New Jersey to Virginia) recorded the unusually rich growth of magnetotactic bacteria and of
other unique and presumptively
eukaryotic iron biomineralizing organisms.
His work has contributed to the emerging consensus that the endosymbiotic theory is correct; this idea proposes that mitochondria, chloroplasts, and perhaps
other organelles of
eukaryotic cells originated as prokaryote endosymbionts, which came to live inside
eukaryotic cells.
Dr. Worthey received her Ph.D. in Genetics from the University of London in 2003 and completed her postdoctoral fellowship at the Seattle Biomedical Research Institute at the University of Washington, working on both
Eukaryotic Genomics and
other high throughput «Omics» projects.