Sentences with phrase «other factors involved here»

If you ask me, there are two other factors involved here: mobile hardware is expensive (forcing users to make a choice between which devices they upgrade), and users tend to be less critical of tablet performance.

Not exact matches

My hope here is that by looking at the research that is being used to form opinions on bedsharing, I can show you what is involved in the research and allow you to come to your own conclusion about the real risks inherent in bedsharing versus the risks of other factors interacting with bedsharing.

This is in accordance with previous reports that decitabine and 5 - azacytidine produce a marked synergistic effect in combination with suberoylanilide hydroxamic acid and romidepsin in T - lymphoma cell lines by modulating cell cycle arrest and apoptosis.26, 27 As a mechanism of action, KMT2D mutations of B - lymphoma cells promote malignant outgrowth by perturbing methylation of H3K4 that affect the JAK - STAT, Toll - like receptor, or B - cell receptor pathway.28, 29 Here our study indicated that dual treatment with chidamide and decitabine enhanced the interaction of KMT2D with the transcription factor PU.1, thereby inactivating the H3K4me - associated signaling pathway MAPK, which is constitutively activated in T - cell lymphoma.13, 30,31 The transcription factor PU.1 is involved in the development of all hematopoietic lineages32 and regulates lymphoid cell growth and transformation.33 Aberrant PU.1 expression promotes acute myeloid leukemia and is related to the pathogenesis of multiple myeloma via the MAPK pathway.34, 35 On the other hand, PU.1 is also shown to interact with chromatin remodeler and DNA methyltransferease to control hematopoiesis and suppress leukemia.36 Our data thus suggested that the combined action of chidamide and decitabine may interfere with the differentiation and / or viability of PTCL - NOS through a PU.1 - dependent gene expression program.

These odds do often have other factors involved such as genetics, ethnicity, bone structure, body weight, certain diseases, and some medications BUT getting enough calcium is a major player here.

The risks involved on the public roads due to the presence of other motorists and several uncontrollable factors is almost completely eliminated here.

The main issue here is how politics and culture have affected the norms of science; my explanation is multi-factorial and involves several inter-related, and each other reinforcing factors: the science - technology link, the rise of social sciences, science's social norms, victimhood culture, and, importantly, the political use of science.

There are other factors involved with life insurance for business purposes, but age and income are the main determining factors for personal coverage which is what we are discussing here.