Sentences with phrase «other gene families»

Other gene families that were dramatically expanded in the octopus include zinc finger transcription factors, which are mainly expressed in embryonic and nervous tissues and are thought to play roles in development.

Prof Bentzen from Dalhousie University said: «Although this study focused on MHC genes in vertebrates, the evolutionary dynamics described in it likely apply to other gene families, for example resistance genes and those which prevent self - fertilization in plants (self - incompatibility loci) that are caught up in their own evolutionary races.»

Not exact matches

The other, a former White House aide to President Obama, tested positive for the BRCA2 gene mutation that has led to breast cancer in her family for generations — and is taking aggressive steps to avoid the same fate.

You become a family not because you share the same genes, but because you share love for each other.»

Our children must have received their genes from other parts of the family because we do have a lot of height on both sides, my husband and I just don't have it.

If you have a strong family history of breast cancer or other cancers, your doctor may recommend a blood test to help identify specific mutations in BRCA or other genes that are being passed through your family.

Fahey, on the other hand, is an unknown, although the family name carries some cache thanks to his cousin, Gene Fahey, the widely respected judge and former city councilman.

The handful of cases that still occur are most likely to affect non-Jews, families carrying mutations other than the distinctly Ashkenazi variants of the Tay - Sachs gene.

My tgf - beta gene was part of a big family of genes, and I began making phylogenetic trees in order to better understand how it was related to the other family members.

An apparently new Variant of human serum albumin, albumin Naskapi, has been found in high frequency in the Naskapi Indians of Quebec and, in lower frequency, in other North American Indians.The family and population data of the albumin are consistent with its inheritance as a simple autosomal trait Controlled by a gene designated Al Naskapi.

Unlike other autoimmune disorders with associated risk factors, APECED is clearly caused by a mutation in a single gene, based on analyses of affected families.

«Our work shows that not only do people with ASD have fewer children than others,» he said, «but in families where a child has ASD, the fact that the parents choose to have fewer children means the genes that predispose to ASD are less likely to be passed on to future generations.»

The researchers — from the universities of Exeter, Puerto Rico and Pennsylvania — believe the cause is a mixture of their genes and other factors such as age, sex and family size.

Affected family members, the group found, had inherited one or two defective copies of ZIC3, a previously unknown gene that appears to code for a transcription factor — a protein that switches other genes on or off.

Most cases of familial hypolipidemia are linked to other gene mutations that cause liver and digestive problems, but in members of this American family with the condition, Musunuru found mutations in the gene for ANGPTL3, and no associated health problems.

Michele Carbone and colleagues, from the University of Hawaii, discovered that members of 4 families, apparently unrelated and living in different US States, shared the identical mutation of a gene called BAP1 that is associated with a higher incidence of mesothelioma, melanoma, renal carcinoma and other cancers.

The researchers also found that wtf4 is a member of a large family of selfish genes, and that at least one other wtf gene also causes meiotic drive, suggesting that the family proliferated due to meiotic drive.

«While naked moles - rats are extreme in many aspects of their biology, we predicted that we would see similar molecular adaptations in the HAS2 gene in other mole - rats and subterranean mammals, yet they remain unique even among other mole - rats within the family.»

She said newborn testing benefits infants with ALD and can help families discover that siblings or other relatives have the gene mutation.

Women with a family history of two or more immediate family members (mother, sister, daughter) with breast or ovarian cancer or with a positive genetic test for mutations in the BRCA1 or BRCA2 genes may be advised to consider having both breasts removed, because they are at high risk of a new cancer developing in the other breast.

Cerebellin is a family of genes that physically interact with other autism genes to form glutamatergic synapses, the junctions where neurons communicate with each other via the neurotransmitter glutamate.

Hunting the culprit genes, Kere, Helsinki colleague Tarja Laitinen, and others collected nearly 900 blood samples from healthy and asthmatic individuals in families afflicted with asthma.

By comparing this region with the DNA from epileptics from six other families, the researchers gradually homed in on a gene called KCNQ2.

The deficits do make some sense, explained Berenbaum: Honeybees usually restrict their diets to a few items — pollen and nectar — and they are scrupulously hygienic, so perhaps those gene families are not as crucial to them as others.

But only 60 % understood the so - called «indeterminate» results, where their relative tested negative for the gene but they and other family members could still be at risk.

It is particularly useful when clinicians want to identify an illness or gene mutation involving a single patient or the patient and two or three other family members, which is the most common clinical situation for undiagnosed diseases.

The researchers then identified children, among other families, who carried the single candidate gene.

Dillin's team then screened 15 other genes from the forkhead family — transcriptional factors important to development and possibly longevity, to which the gene for daf - 16 belongs — to see if any of them were necessary to increase longevity after dietary restriction.

One of the «hits» was Lhx1, a member of a family of genes whose protein products affect development by controlling the activity of other genes.

When the team compared E. rubrum's gene families against those in two other halophilic species (Wallemia ichthyophaga and Hortaea werneckii), they found that high acidic residues were common in all three species, a general trait all salt - tolerant microbes share.

Two, JARID2 and JMJD3, are part of a family of genes called the Jumonji family, which are known to influence sex differentiation in other animals.

Professor Michael Lisanti, from The University of Manchester — part of Manchester Cancer Research Centre, said: «We know that high breast density can greatly increase a woman's breast cancer risk as well as other factors such as aging, family history and presence of mutations in genes such as BRCA 1 and BRCA 2.

By also examining this genetic region in two other families with similar disorders, the researchers were able to pinpoint a mutation in a specific gene, NT5E, which is involved in breaking down calcification in the arteries.

The scientists found that the genes for each toxin family were also used in other parts of the body in the snake's evolutionary past and even today.

Focusing their search on receptors not known to respond to any odor, the researchers identified one family of genes that appeared to be expressed in olfactory neurons but not in other tissues.

In addition to Otop1, there are two other related genes in vertebrates (Otop2 and Otop3), and this gene family is represented in the fruit fly Drosophila melanogaster.

In 77 families, they did not find BRCA mutations, but did find changes in other genes they say are definitely linked to breast cancer, such as TP53 and CHEK2.

The Arizona researchers studied whether cage conditions affect mice with one copy of a gene called fibulin - 4, a member of a family of genes believed to code for proteins that stabilize the connective tissue found between cells in arteries and other blood vessels.

Normally, FOXP2 coordinates the expression of other genes, but in affected members of the KE family, it was broken.

The gene is normal in the rest of the family and in 364 other unrelated, unaffected people.

This sort of horizontal gene transfer across families of bacteria — other relatives include Samonella, Shingella and the plague - causing organism Yersinia — marks a significant finding, Blattner notes.

This is in contrast to the well - characterized VRC01 - like family of CD4 - binding site antibodies identified in multiple HIV - positive donors, which share both a heavy chain V gene precursor and unusual features at a DNA sequence level which could allow sequencing - based identification of other similar antibodies in distinct patients [53].

Clustering these gene models with 13 other plant species resulted in 20,646 gene families, of which 1554 are predicted to be unique to conifers.

They also chose a gene target that might itself be problematic, given that it is part of a closely linked family of globin genes with highly related sequences, making it hard to target one without affecting the others.

«The lessons we learned about cardiac gene networks from this family and their mutation will inform the development of treatments not only for their form of heart disease, but for many others.»

Genes from this family have become leading candidates for other forms of MODY as well as common late - onset NIDDM.

GeekWire Award finalists include Bezos Family Immunotherapy Clinic and Nohla Therapeutics, among others; Scientists read infection history in immune genes; and two Hutch faculty members in final class of Kimmel Scholars.

SLC16A11 belongs to a family of genes known to transport molecules across cell membranes, but the proteins that genes produce can perform many different roles in the body, and they can be active in some tissue types but not others.

Second, says Brody, his study has found a host of other genes that «control a whole family of metabolites» in the folate and B12 pathway.

Recently, some other cytokines (such as tumor necrosis factor) or chemical drugs were also found to up - regulate several IFN - inducible gene family members (including RIG - G) through production of type I IFNs (37, 38), further indicating that the induction of RIG - G by ATRA in NB4 cells was tightly related with an IFNα autocrine pathway.