Sentences with phrase «other gene sequences»

Several other gene sequences found in the water and the ice came from pigs, chickens and cows.

Not exact matches

That's attached to the progress of sequencing technology, the ability to edit cells, and other gene editing approaches have been transformative in the immunotherapy world in recent years.

This dataset contains millions of genomic sequences from a diverse set of rice varieties that, when combined with phenotyping observations, gene expression, and other information, provides an important step in establishing gene - trait associations, building predictive models, and applying these models to breeding.

The DNA segments that carry genetic information are called genes, but other DNA sequences have structural purposes, or are involved in regulating the expression of genetic information.

In the new research, the UB scientists found they could reverse those social deficits with a very low dose of romidepsin, which, they found, restores gene expression and function using an epigenetic mechanism, where gene changes are caused by influences other than DNA sequences.

An international team led by researchers with the Lawrence Berkeley National Laboratory (Berkeley Lab) has developed a new technique for identifying gene enhancers — sequences of DNA that act to amplify the expression of a specific gene — in the genomes of humans and other mammals.

Night after night Rienhoff tediously compared his daughter's DNA sequence with reference sequences stored in several major genomic databases — Ensembl, Heidelberg, and the UCSC Genome Bioinformatics gene bank, among others.

Even after the principles of epigenetics came to light, it was believed that methylation marks and other epigenetic changes to a parent's DNA were lost during the process of cell division that generates eggs and sperm and that only the gene sequence remained.

On the other hand, by deciding that an EST sequence does not provide an adequate written description of a claim directed to «a gene,» the PTO has preserved the possibility for a gene itself to be patented once its full - length sequence is determined.

As for the identities of Mendel's other four genes, Weeden says he expects them to be revealed in the next few years as more plant genomes give up their sequences.

Luckily, along came Armstead and his colleagues, who were working to precisely locate the sequence of a gene called staygreen (sgr) in the meadow grass Festuca pratensis, some variants of which remain green in drought and other unfavorable conditions because they are unable to break down a green pigment.

The human (and all the other) genome projects were predicated on the reasonable assumption that spelling out the full sequence of genes would reveal the source of that diversity of form and attributes that so readily distinguish worm from fly, mouse, chimp and human.

There were about 40 genomes of bacteria sequenced at that time, and what you could do was compare your gene of interest to other genomes to see if they contained something similar.

«By inserting the new sequence into the DNA, perhaps they are altering the gene in some other way,» he says.

They argue that anyone whose genome is sequenced for any medical reason should automatically learn whether 57 of their genes put them at risk of certain cancers, potentially fatal heart conditions, and other serious health problems.

Trent and others says that the same mechanism might be at work in genes linked to other cancers, such as breast and prostate cancer, which have been found to contain similar «harmless» sequence variations.

As the cost of gene sequencing drops, DNA being sequenced for one purpose may yield many other secrets, such as the risk of certain cancers and Alzheimer's disease.

Surprises include the discovery of about 20 eukaryotic genes; other bacteria that have been sequenced have had few, if any, such genes.

They also ruled out other possibilities, including the gene spontaneously mutating back to the normal form, the existence of more than two copies of the hothead gene, or closely related DNA sequences providing a template for repairs.

Berninger and others have previously shown that Sox2, Ascl1, and other transcription factors — proteins that bind to specific DNA sequences to control the activity of genes — can induce the nonneuronal «support cells» known as glia to turn into neurons.

While the genetic stock of the entire clan of indigobirds is remarkably uniform, certain gene sequences pop up more often in some species than others.

Ressler then wanted to see whether Oprl1 could be linked to PTSD in humans, so looked at the gene's sequence in approximately 1,800 highly traumatized civilians, some of whom had PTSD and others who did not.

The team has also found that in hothead mutants, other faulty genes mysteriously revert to the sequence of earlier generations too.

They enable molecular biologists and geneticists to selectively chop DNA into pieces, which can then be assembled into new versions of the gene, inserted into the genomes of other organisms, or sequenced as part of an effort to map an organism's genetic material.

Suspecting that the other four carried a new Ehrlichia species, the researchers sequenced the bacterial gene in their blood and compared it to a database containing the sequences of known infectious bacteria.

At Darwin's lab, eight sequencing machines ran around the clock, decoding the DNA samples that had been collected from Ginger and the others, while Schellenberg and George Martin and their colleagues combed through the results for suspect genes.

Over the longer term, the identification of the coffee tree genome sequence opens up new possibilities for varietal improvement, knowledge of the specific functions of the genes (in particular those specific to coffee trees), the possibility of transferring results to other species, and refining diagnostic tools for the function of the plant.

A catalogue of genes and repeated sequences was then created and validated, allowing for a comparison with other plants.

They then used next generation sequencing — a state - of - the - art method to rapidly measure gene expression — to sequence and quantify the thousands of genes that are expressed in hair cells, in comparison with other cells in the ear.

People with different DNA sequences in the gene producing the OR7D4 receptor respond differently to this smell — some people find it foul, some sweet, and others can not smell it at all.

Now that the entire salmon genome has been sequenced and made available, Dr Rødseth is certain that it will become cheaper and faster to find other significant genes in the future.

A chromosome is, minimally, a very long, continuous piece of DNA, which contains many genes, regulatory elements and other intervening nucleotide sequences.

Matches between new genes from other species, including mammals, and these E. coli sequences have often helped researchers pin a name and function on their discoveries.

The toxin did not appear to be altering gene sequences; instead, Skinner and colleagues found, vinclozolin was somehow causing other chemical groups to latch onto certain genes, changing their expression (Science, 3 June 2005, p. 1391).

«Genes code for the sequence of amino acids in proteins, and some are involved in the regulation of the expression of other genes,» he Genes code for the sequence of amino acids in proteins, and some are involved in the regulation of the expression of other genes,» he genes,» he says.

Using next - generation RNA sequencing and other advanced technologies, the researchers identified a previously unknown gene involved in betalain synthesis and revealed which biochemical reactions plants use to convert the amino acid tyrosine into betalains.

What we were surprised to find out was that the real differences we could detect in terms of when we did the swap experiments to say which yeast could outperform the other — what we learned was that the GAL1 gene, that the part [of] that, the DNA sequence is outside of the GAL1 gene, it acts as a switch to turn up or turn down GAL1 expression, that had evolved considerably from the ancestral situation; and same for the GAL3.And then what had happened was that each function had been optimized, that GAL3 had sort have been tuned to be sort of a loosely regulated kind of available anytime sensor of galactose and GAL1 had evolved to be an incredibly tightly regulated, in fact, it's the most tightly regulated gene you know of in yeast.

Douglas Thomas, associate professor of medicinal chemistry and pharmacognosy at UIC, and co-workers discovered that nitric oxide plays an important role in epigenetics — heritable alterations in gene expression caused by mechanisms other than changes in DNA sequence.

To begin to grapple with those questions, the researchers involved in the new study first selected as «seeds» the nine genes that have been most strongly tied to ASDs in recent sequencing research from their labs and others.

Researchers report that one tiny variation in the sequence of a gene may cause some people to be more impaired by traumatic brain injury (TBI) than others with comparable wounds.

Steve: The changes were in those other sequences that determine how those genes get expressed, when they get turned on and off and in what numbers.

By using sequences of RNA that match specific gene sequences in a pest, RNAi should leave other species unscathed.

One general benefit of the RNAi approach, Zhang says, is that researchers can selectively target specific insect pests by targeting species - specific gene sequences; this avoids the blanket destruction of other insect species seen with many insecticides, he explains.

«As we sequence more and more achromatopsia patients, we're likely to identify other genes,» said Dr. Tsang.

Using the recently completed tomato genome sequence they then identified the gene as SlGLK2 — a so - called transcription factor, which controls when and where other genes are switched on or off.

To identify genetic changes likely to be responsible for the giraffe's unique characteristics, including sprints that can reach 37 miles per hour (60 km / h), Cavener and Agaba compared the gene - coding sequences of the giraffe and the okapi to more than forty other mammals including the cow, sheep, goat, camel, and human.

First, samples of leaves from these plants are collected for in vitro cultures to isolate the fungi; then the DNA and RNA of fungi are extracted to sequence them and, through bioinformatic analysis, the researcher can determine the expression, the presence or absence of genes in the genomes of a species against each other.

The genome shares about 60 % of its genes with the other invertebrates completely sequenced, such as the nematode and fruit fly, whereas about 5 % match sequences found only — up to now, at least — in the human, mouse, and puffer fish genomes.

Finally, they patched together a transposon based on computer alignments and their own judgment from their knowledge of similar sequences in other genes.

In some cases, the missing pieces can be picked up by comparing the new sequences with known sequences of genes from other species.