Sentences with phrase «other gene variations»

However, if «feeling worse» lasts more than few days, this could be due to overmethylation, other gene variations, or a sensitivity to the supplements; and the supplements should be discontinued.
This study showed the two subtypes have different genetic origins and involve a dramatically different number of chromosomal rearrangements, mutations and other gene variations.

Not exact matches

Other research shows that ADHD children with a particular gene variation have thinner tissue in the area of the brain that's associated with attention.
Sleep - deprived people with two other variations of the gene tend to perform much more poorly on the same kinds of tasks, the researchers found.
Based on the core principles of behavioral genetics, if genetics explain variations in distrust and trust behaviors, then identical twins should behave more similarly to each other than fraternal twins, since the genes of identical twins are shared, while the genes of fraternal twins are only imperfectly correlated, Reimann said.
For example, some variations of a gene are better suited for a dry climate, while other variations of that same gene are better suited for wetter environments.
To find other genes associated with these traits, researchers will need to scan the genomes of even more women and look for less common genetic variations, says Kári Stefánsson, CEO of deCODE Genetics in Reykjavik, Iceland.
Trent and others says that the same mechanism might be at work in genes linked to other cancers, such as breast and prostate cancer, which have been found to contain similar «harmless» sequence variations.
Genetic factors can contribute to the degree of longevity in at least two important ways: An individual may inherit certain genetic variations that predispose him or her to disease that decreases longevity; other gene variants may confer disease resistance, thereby increasing it.
In all, the study included the data of more than 23,000 people to show that approximately 12 percent of a person's variation in delay discounting can be attributed to genetics — not a single gene, but numerous genetic variants that also influence several other psychiatric and behavioral traits.
The results, which focus on two choices near the start of embryo formation, show that, when cells are making decisions about what to become, there is greater variation in the activity of the genes in different cells — the same genes may be turned on in some cells and off in others.
A third of white people have gene variations that make it harder for them to quit cigarettes, and may predispose them to other addictive behaviours
Such high levels of genetic variation poise mosquito populations to rapidly evolve in response to our efforts to control them whether that be with insecticides or any other control measure, including gene drive.»
«All three predictions were met: facial traits are more variable and less correlated than other traits, and the genes that underlie them show higher levels of variation,» Nachman said.
Researchers report that one tiny variation in the sequence of a gene may cause some people to be more impaired by traumatic brain injury (TBI) than others with comparable wounds.
And the gene variation has effects on hundreds of other genes as well, causing a cascade effect that the researchers have not yet fully charted.
Although bacteria have a seemingly limitless capacity to alter their genes by swapping bits of DNA between strains, this mechanism doesn't seem enough to account for the swift pace of change and the high variability of E. coli and other strains.Thomas Cebula of the U.S. Food and Drug Administration (FDA) wondered if this rapid evolution is being driven by microbes capable of much faster - than - normal variation.
Across all four cancer types, the new method of selecting candidate genes based on inter-tumor variation in gene expression outperformed the other methods, including the standard method of comparing mean expression in adjacent normal and tumor tissues.
Scientists have discovered a previously unrecognized gene variation that makes humans have healthier blood lipid levels and reduced risk of heart attacks — a finding that opens the door to using this knowledge in testing or treatment of high cholesterol and other lipid disorders.
Previous studies have suggested, among other things, that differences in dogs» ability to communicate are associated with variations in the genetic material located close to the gene that codes for the oxytocin receptor.
Finding these genes means we can now investigate what the gene variations are doing and how they interact with each other to see how AMD is formed.
One of their findings was a variant in a gene called Ret that had not been previously associated with the disease, although other variations in Ret had been fingered as culprits.
Howard was especially curious about how variations of base pairs within the two genes interacted with each other to impact asthma.
This relatively low level of arsenic inside me was good news; Mattingly informs me that I have mutations in 22 of the 1,400 genes shown to interact with arsenic, including a variation in the ABCB1 gene that may inhibit my ability to expel the metal (and other toxins) from my body.
«We're confident that applying this same approach to a lot of new data will help us discover additional genomic variations and identify specific genes that play a role in schizophrenia and other psychiatric conditions.»
Several candidate gene studies suggest that variations in HLA class 1 and other genes contribute to differences in antibody response to influenza vaccines [15], [69], [70].
These genetic variations were found in regions of the DNA that were near genes involved in Parkinson's disease and other brain disorders.
This section describes the wheat genome assemblies available, gene models, using EnsemblPlants to access wheat data, accessing wheat expression data, finding variation data and finding the wheat orthologue of genes from other species.
Other accomplishments in this area include the mapping of variation in the FTO gene for obesity, characterizing the role of interleukin (IL)-6, IL - 10, and IL - 1RA in obesity and insulin resistance in African Americans (AA), and determining the loci associated with CRP, IL - 10, IL - 1Ra, and IL - 6 levels in a GWAS of AA.
In order to assess the impact of PMI on gene expression we need to account for the possible effect of other pre-mortem variables on the variation of gene expression.
If it's a noisy, random process, however, the two genes» activity would differ, with some cells producing lots of green and others lots of red, or any number of other variations.
It's this diversity of looks that make man's best friend the perfect laboratory for connecting sets of genes to particular traits and understanding the molecular mechanisms that govern variation in dogs as well as humans and other mammals.
The researchers in this study have pinpointed variations in a specific gene — MC1R — that are directly related to how old people appear to others.
This means that they are frequently shuffling their genetic information between each other to create lots of new variations of var gene and consequently, lots of variations of PfEMP1.
deCODE has discovered a gene with certain variations that predispose to obesity and others that predispose to thinness Reykjavik, ICELAND, September 30, 2003 — deCODE genetics (Nasdaq / Nasdaq Europe: DCGN) today announced that it has achieved a milestone under its...
This section invites manuscripts describing (a) Linkage, association, substitution or positional mapping and epigenetic studies in any species; (b) Validation studies of candidate genes using genetically - engineered mutant model organisms; (c) Studies focused on epistatis and gene - environment interactions; (d) Analysis of the functional implications of genomic sequence variation and aim to attach physiological or pharmacogenomic relevance to alterations in genes or proteins; (e) Studies of DNA copy number variants, non-coding RNA, genome deletions, insertions, duplications and other single nucleotide polymorphisms and their relevance to physiology or pharmacology in humans or model organisms, in vitro or in vivo; and (f) Theoretical approaches to analysis of sequence variation.
In this study, the research team searched for gene mutations - or other variations in the genome - that may have a direct effect on the risk of pathologically low - bone density among a large set of sequence variants.
However, being a complex multistep process, cancer cytogenetics are broadened to «cytogenomics,» with complementary resources on: general databases (nucleic acid and protein sequences databases; cartography browsers: GenBank, RefSeq, UCSC, Ensembl, UniProtKB, and Entrez Gene), cancer genomic portals associated with recent international integrated programs, such as TCGA or ICGC, other fusion genes databases, array CGH databases, copy number variation databases, and mutation databases.
Other uses of having a known link between multiple DNA sequencing reads includes studies of structural variations in for instance cancer cells, and when linking functional genes to taxonomic groups in microbial communities.
Here, we discuss and illustrate the strengths and weaknesses of approaches for the annotation and classification of important elements of protein - coding genes, other genomic elements such as pseudogenes and the non-coding genome, comparative - genomic approaches for inferring gene function, and new technologies for aiding genome annotation, as a practical guide for clinicians when considering pathogenic sequence variation.
The paucity of single nucleotide diversity among breeds is consistent with other studies (29 — 32) and stands in stark contrast to the abundance of coding repeat variation we found in these same genes known to be involved in the developmental processes under selection in the radiation in dog breed morphologies.
DLGAP2, the other gene listed in the accompanying graphic, has also been implicated in the development of autism in a copy number variation (CNV) analysis of people with ASD.
Variations in a particular gene may help explain why some people appear more youthful than others, researchers say.
The focus of the conference was connecting how epigenetics (cellular and physiological phenotypic trait variations that are caused by external or environmental factors that switch genes on and off and affect how cells read genes instead of being caused by changes in the DNA sequence — in other words nutrition and lifestyle choices) impact whether or not an individual actually develops a specific health issue even though they have a SNP mutation.
Other genes almost certainly play a role in this variation, though they are yet to be identified.
Related to this question, recent research suggests that particular polymorphisms, often those linked to risk for pathology, make the individual more susceptible to be influenced by parenting and other experiences.24 - 26 For example, children carrying the 7 - repeat variation of the DRD4 appear to benefit more from interventions directed to prevent behaviour problems than those carrying other variations of the gene.24 Nonetheless, further research is needed on how and to what extent EC skills may be influenced by the interplay between constitution and experience.
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