This process — known as backcrossing — helps to remove the influence of
any other genetic differences.
To make sure that the differences were really due to the DISC1 variation and not to
other genetic differences, graduate student Ha Nam Nguyen spent two years making targeted genetic changes to three of the stem cell lines.
Because only some of the hybrids were fertile some of the time, Oliver says there must be
some other genetic difference that distinguishes the two species.
Not exact matches
The second is slightly more friendly to non-science trained people but may still require some referencing of
other sources to understand various details (e.g. the
difference between mitochondrial and nuclear
genetic sequencing).
The
difference between Paleoamerican and modern Native American facial features is likely a combination of additional waves of migration from Siberia, via Beringia, and
genetic drift, a gradual change in appearance and
other traits as populations divide, migrate and adapt, says Jim Chatters, a Seattle - area anthropologist who led the multinational study of Naia.
It also sought to match epigenetic changes and
genetic differences to the physical characteristics of each cell type and use this knowledge to understand how these can lead to blood disorders, cancer and
other complex diseases.
Some women's biological clocks tick faster than
others, and now, researchers have uncovered the first
genetic evidence to explain
differences in the length of women's fertile lives.
If there is any
genetic basis at all to racial IQ test - score
differences, it is indeterminate and poorly quantified, with recent studies estimating IQ heritability to be anywhere from nearly zero to over 80 percent, and strongly countered by
other studies showing that environment counts most.
Further work showed that
genetic differences affecting some of these characteristics are linked to increased risk of heart attack, or to rheumatoid arthritis and
other common autoimmune diseases.
«In this sense, pending the collection of new samples of this new Mediterranean Osedax species to study its morphological characteristics, the only
differences that we have been able to determine in relation to
other species are
genetic,» notes Sergi Taboada.
None of the
other genetic groups could be subdivided, suggesting that there isn't enough
genetic difference to distinguish people from northern versus southern Europe, for example.
Normally, sweet and bitter sensations suppress each
other, so in foods and beverages,
genetic differences in bitter perception can also influence perceived sweetness.
So, the new findings support the idea that
genetic differences expressed early during brain development may have a lot to do with the development of bipolar disorder symptoms — and
other mental health conditions that arise later in life, especially in the teen and young adult years.
Molecular biologist Matt Kaeberlein of the University of Washington in Seattle says the results are in line with work from his lab showing that slight
differences in growth conditions, the
genetic makeup of the yeast or
other factors can change the outcome of the experiment.
The question of binge drinking patterns and mortality is far from solved, and there may be
genetic differences or
other covariates not yet discovered, which play a role and could explain the different empirical findings.»
After collecting information from school counselors about any social difficulties experienced by the girls, Skuse's group found that 40 % with the maternal X chromosome were likely to have problems at school, versus only 16 % of girls with the paternal X. «It seemed to us there could only be a
genetic explanation for that,» Skuse says, because he says there were no
other differences between the two sets of girls.
These maps, they say, will show everything from relative sizes of anatomical features to
differences in brains associated with age, race, gender, educational background,
genetic composition, and
other distinguishing characteristics.
Another thing the team didn't consider was
genetic differences among individuals: Some monkeys are naturally more susceptible to adversity whereas
others are more resilient, he says.
Sudmant, a UW graduate student in genome sciences, said, «Gathering this data is critical to understanding
differences between great ape species, and separating aspects of the
genetic code that distinguish humans from
other primates.»
The
genetic differences were so large that the two populations might not be able to breed with each
other.
By comparing the
genetic differences with
differences in silk properties, Hayashi's team has found that those motifs appear to influence strength, elasticity, and
other features.
But the finding that all these
genetic differences trigger the same cellular pathway provides hope for
others.
Cancer researchers are just beginning to investigate the extent and significance of
genetic differences among tumor cells — either cells within a discrete tumor or between a primary tumor and metastases in
other parts of the body.
In some individuals there were significant
genetic differences between tumor sites, suggesting early metastatic spread; in
others, there was little
difference between a primary tumor and its metastases.
Research has identified sex and
genetic differences in gastrointestinal, cardiovascular and neurological systems, among
others.
Other chapters apply this to the genetics of immune systems, the evolutionary benefits of sexual reproduction,
genetic differences among human populations, the origin of life and more.
These
genetic differences have often been blamed when chemotherapy or
other treatments have been unsuccessful, as it was believed that the therapy may not have targeted all of the cells within the tumor.
Previous studies have suggested, among
other things, that
differences in dogs» ability to communicate are associated with variations in the
genetic material located close to the gene that codes for the oxytocin receptor.
There is no doubt that most of the
genetic differences between humans and
other apes — and between different human populations — are due to
genetic drift.
Fernández says that while «both studies support each
other» in pointing to a sea route, the
differences between them could be due to the
genetic profiles of Middle Easterners having changed since ancient times.
To do that, we would need to know what was causing some individuals to leave more surviving descendants than
others, and to be sure that that selection pressure would be maintained for hundreds or thousands of generations, and know what the
genetic and phenotypic basis for the variance underlying these
differences was.
Such
genetic differences may explain why some people are more susceptible to mercury poisoning than
others.
Meanwhile,
other studies have found that language
differences restricted gene flow in recent times in Europe, suggesting that cultural barriers might have limited
genetic diversity more consistently than occasional local bottlenecks.
These mutations varied tremendously between populations, which counters a popular view that many of the
differences between populations arose by chance or were
genetic variants that hitchhiked along with
other genes that improved reproductive success, says biological anthropologist Henry Harpending of the University of Utah, Salt Lake City, and co-author of another study of accelerated evolution.
There were small
differences in the virus»
genetic material compared to
other samples of Zika virus, did they cause the virus to be exceptionally aggressive?
For this family and so many
others who would come after them, Preimplantation
Genetic Diagnosis is the
difference between passing on a life - threatening disease and giving their children the best chance at a healthy, happy future.
(LA JOLLA, CA)-- February 11, 2016 — The J. Craig Venter Institute (JCVI) researcher Hernan Lorenzi, Ph.D., in collaboration with L. David Sibley, Ph.D., Washington University School of Medicine, and a team of international researchers have published a paper outlining key
genetic differences in strains of Toxoplasma gondii which shed light into the biological and virulence
differences between T. gondii strains and between
other closely related parasites.
«The increase in
genetic risk was independent of other known risk factors, suggesting that testing for multiple genetic differences is clinically useful to evaluate risk and guide management,» senior author Dr. Guillaume Paré, an associate professor of medicine at McMaster University and Hamilton Health Sciences in Hamilton, Canada, and the director of the Genetic and Molecular Epidemiology Laboratory, said in a sta
genetic risk was independent of
other known risk factors, suggesting that testing for multiple
genetic differences is clinically useful to evaluate risk and guide management,» senior author Dr. Guillaume Paré, an associate professor of medicine at McMaster University and Hamilton Health Sciences in Hamilton, Canada, and the director of the Genetic and Molecular Epidemiology Laboratory, said in a sta
genetic differences is clinically useful to evaluate risk and guide management,» senior author Dr. Guillaume Paré, an associate professor of medicine at McMaster University and Hamilton Health Sciences in Hamilton, Canada, and the director of the
Genetic and Molecular Epidemiology Laboratory, said in a sta
Genetic and Molecular Epidemiology Laboratory, said in a statement.
From previous research on
genetic instability, conducted by the Pearson lab and
others, the researchers suspected that the dramatic
difference between the mice might boil down to variances in one particular biological process, called mismatch repair, and more specifically one of its major players, the MSH3 protein.
This work presents a genomic analysis of the UM270 gene functions as compared to
other available pseudomonad genomes, highlighting the
genetic and functional
differences between each strain of this group of fluorescent and plant growth - promoting bacteria.
The team's work highlights this by presenting a comprehensive view of genome evolution on many different levels (e.g.,
differences in ploidy, aneuploidy,
genetic variants, hybridization, and introgressions) that is difficult to obtain at the same scale and accuracy for
other eukaryotic organisms.
These regions, however, lie several hundred kilometers apart from each
other and the generally high
genetic difference between the populations does not suggest high rates of exchange.
Mosquitoes share some components of the sex determination pathway with
other insects, but also have unique
genetic controls that help establish the remarkable
differences between males and females.
Our analysis infers areas where there's more
genetic difference than you'd expect per unit of geographic distance, and
other areas where there's less.
The striking
differences observed in Themis1 - deficient rats of the BN and LEW
genetic backgrounds suggest that an epistasis between Themis1 and
other gene (s) controls Treg function.
Some athletes have saltier sweat than
others due to simple
genetic differences, diet, sweat rate, and heat acclimatization.
On the
other hand, «a brisk one - hour daily walk reduced the
genetic influence towards obesity, measured by
differences in BMI by half.»
For her and countless
other patients, things like chronic stress, poor diet, lack of exercise, inflammation, insulin resistance, infections, toxic exposure, and
genetic differences mean these core nutritional imbalances have persisted for years or decades, inhibiting the body's ability to heal, recover, and remain healthy.
The «tight junction» problem is more of a problem in some people than
others, and this
difference is very much
genetic.
An adaptation of R.J. Palacio's novel, director Stephen Chbosky, Steven Conrad, and Jack Thorne's screenplay does such a sympathetic job of communicating the story of a 10 - year - old boy, who was born with a
genetic disorder that resulted in facial
differences, that we aren't really considering the lives of the
other characters on screen.