Sentences with phrase «other genetic drivers»
«More and more we're showing that cancers caused by ROS1 or many other genetic drivers may be treated with similar drugs no matter where the cancer lives in the body.»
http://www.coloradocancerblogs.org/ Not exact matches
Cells with weak driver mutations needed other background mutations to grow well in antimicrobial drugs, however cells with strong driver mutations developed resistance to drugs regardless of the genetic background.
However, with any genetic background, cells with strong driver mutations could «leapfrog» and outcompete other cells growing in the drugs.»
The new finding is the latest evidence supporting a growing precision medicine model of psychiatric disease in which disruptions of certain genes during brain development contribute to a person's risk for multiple psychiatric disorders, with other genetic or epigenetic drivers, random developmental events, or environmental influences determining the specific disease an individual develops, said senior author Benjamin Cheyette, MD, PhD, an associate professor of psychiatry and a member of the UCSF Weill Institute for Neurosciences and the Kavli Institute for Fundamental Neuroscience at UCSF.
Elderly fathers pass along many more DNA errors than do young ones — a source of genetic diversity, but also a possible driver of autism and other disorders.
In the last decade the identification of genetic drivers of melanoma cell which regulate proliferation and survival - such as BRAF and other activators of the MAP - kinase pathway - along with the recent development of immunotherapy has taken away in many cases the invasive treatment of melanoma as an option.