Sentences with phrase «other genomic approaches»

Not exact matches

«When you start to do systematic studies of biological systems and you gather information from different angles — meaning genomics, proteomics, and other approaches — and combine this information, you end up being able to do discoveries which would not be possible under each individual set of information,» says Figeys.

And other options do exist: funding from other organizations for evolution - related research has increased, especially for the genomics approaches (large - scale DNA sequencing and bioinformatics) that underpin molecular evolution research.

«We're confident that applying this same approach to a lot of new data will help us discover additional genomic variations and identify specific genes that play a role in schizophrenia and other psychiatric conditions.»

Highlight best practices and lessons learned to enable others to effectively implement genomic medicine approaches

We are currently quantifying the genetic variability of this gene as well as other closely linked genes using a genomic approach.

We are investigating these and other allied questions using evolutionary genomic approaches, by performing comparative analyses of plant genomes, transcriptomes and proteomes.

This section invites manuscripts describing (a) Linkage, association, substitution or positional mapping and epigenetic studies in any species; (b) Validation studies of candidate genes using genetically - engineered mutant model organisms; (c) Studies focused on epistatis and gene - environment interactions; (d) Analysis of the functional implications of genomic sequence variation and aim to attach physiological or pharmacogenomic relevance to alterations in genes or proteins; (e) Studies of DNA copy number variants, non-coding RNA, genome deletions, insertions, duplications and other single nucleotide polymorphisms and their relevance to physiology or pharmacology in humans or model organisms, in vitro or in vivo; and (f) Theoretical approaches to analysis of sequence variation.

MELGEN will explore emergent new techniques, for example the Sanger Institute (GRL) and ServiceXS will explore new approaches to genomic data generation from such samples and from fresh tumour and, critically, with other participant groups develop new statistical / bioinformatic approaches to data analysis.

In this first - of - a-kind survey, researchers used a forward - looking approach to screen the genes that produce tyrosine kinases — reasoning that somewhere in this genomic landscape they might encounter novel mutations that spur colon cancer and other types of cancer.

And through approaches that allow the characterization of the entire proteome, researchers are integrating genomic analysis with the analysis of the proteins in tumor cells to learn, in detail, how cancer - associated mutant proteins affect other proteins.

Here, we discuss and illustrate the strengths and weaknesses of approaches for the annotation and classification of important elements of protein - coding genes, other genomic elements such as pseudogenes and the non-coding genome, comparative - genomic approaches for inferring gene function, and new technologies for aiding genome annotation, as a practical guide for clinicians when considering pathogenic sequence variation.