Sentences with phrase «other human disorders»

However, they say the work at least proves the potential for mRNA therapy to successfully treat not only hemophilia B but also other human disorders, such as hemophilia A (caused by faulty clotting factor VIII) or a variety of diseases of the liver, central nervous system, lung and eyes.

This innovative model allows the researchers to test viable new drugs for this disease, and it provides a potential solution to studying other human disorders of aging in mice.

Unlike most other human disorders, it severely affects two individuals — the mother and the infant.

Not exact matches

Scientists know how to make fruit flies and mice smarter, and efforts to come up with a treatment for Alzheimer's and other neurological disorders are leading to drugs that enhance memory and cognition in humans.

Managers killed those programs (including one highly anticipated drug aimed at coronary disorders that was about to head into human trials) and prioritized others where there was a clear genetic target for the drug.

When the image of God entered into the species which is humankind, that species was ordained to find its order on a plane other than the animal, and because of the presence of that divine image, dominance on the human plane is not a natural order but a disorder.

Furthermore, despite the claim that evolution has no application, phylogenetic comparisons of humans and other organisms allows us to identify the precise location and putative function of genes responsible for developmental disorders.

When one views the world with no definite theological bias one way or the other, one sees that order and disorder, as we now recognize them, are purely human inventions.

Although in terms of its biological, economic and mental determinisms the human earth, emerging from war, may be seen to be more tightly fastened upon itself than ever before, in its other and freer aspects it may give a first impression of growing disorder.

It ranges from social / emotional wellness — an ability to form satisfying relationships with others, to play, communicate, learn, and experience the full spectrum of human emotions — to the disorders of very early childhood.

«Our data only refers to Rett,» he says, «but it makes one wonder about autism and other human brain disorders.»

In certain rare human medical disorders, the question of how long people can remain awake raises other surprising answers, and more questions.

Now, in this week's issue of the Proceedings of the National Academy of Sciences, Thomas Albright and Ricardo Gil - da - Costa of the Salk Institute for Biological Studies describe a model system that completes the bridge between cellular and human studies of schizophrenia, an advance that should help speed the development of therapeutics for schizophrenia and other neurological disorders.

Ostrander says that by identifying other dog genes for body size and for traits such as leg length and head shape, researchers may learn more about growth and its disorders — especially cancer — in humans and their best friends.

If so, it would mean that, rather than being an 18,000 - year - old representative of a new species, the hobbit was just a modern human with a growth disorder that left it with a brain the size of a grapefruit, among other odd traits, which is what critics have argued all along.

A neuroscientist at Rutgers University - Newark says the human brain operates much the same whether active or at rest — a finding that could provide a better understanding of schizophrenia, bipolar disorder and other serious mental health conditions that afflict an estimated 13.6 million Americans.

The human cell - based disease model is expected to lead to a better understanding of these disorders and other illnesses, Hsiao said.

It implies that an EBV vaccine, if it were ever developed, could prevent not just kissing disease, but many other disorders, similar to the way the human papillomavirus vaccine reduces cervical cancer risk.

Then there are the bees: Regardless of whether honeybees become extinct as a species as a result of colony collapse disorder, climate change and other threats, the local extinction of various honeybee populations and the pollination they provide could spell disaster for human agriculture.

Like humans, songbirds such as zebra finches (above) can learn vocalizations, and this similarity suggests they could serve as models for research on Huntington's disease and other neurodegenerative disorders that affect speech and vocalization.

By now, European astronauts had hoped to be established in their space laboratory called Columbus, where they would be melting and solidifying conductive metals, studying microgravity effects on single - celled organisms, investigating human balance disorders, and carrying out dozens of other experiments.

Two of the world's largest professional societies of human geneticists have issued a joint position statement on the promise and challenges of non-invasive prenatal testing (NIPT), a new procedure to test blood drawn from pregnant mothers for Down syndrome and other chromosomal disorders in the fetus.

«There are a range of metabolic diseases and other liver disorders where if you fix a mutated gene you might be really able to have an impact on human health,» Anderson says.

Researchers also found higher levels of expression of the gene MET, which is linked to autism spectrum disorder, in the human prefrontal cortex compared to the other primates tested.

The real test, Conboy says, will come in clinical trials that aim to block B2M — or other related molecules — to treat or prevent memory disorders in humans.

«That might underlie the WS super-social aspect and their gregarious human brain, giving insights into autism and other disorders that affect the social brain.»

Elisabeth Gillis, MSc, a PhD student in the Centre for Medical Genetics at Antwerp University Hospital, Antwerp, Belgium, will tell the annual conference of the European Society of Human Genetics that she and colleagues from seven other countries are the first to link this particular genetic mutation to serious aortic disorders.

If the findings translate to humans, they could lead to new ways to treat depression, anxiety, and other mental disorders.

If the new mechanism also operates in the human brain and can be potentiated, this could become of clinical importance not only for stroke patients, but also for replacing neurons which have died, thus restoring function in patients with other disorders such as Parkinson's disease and Huntington's disease,» says Olle Lindvall, Senior Professor of Neurology.

Scientists have discovered a previously unrecognized gene variation that makes humans have healthier blood lipid levels and reduced risk of heart attacks — a finding that opens the door to using this knowledge in testing or treatment of high cholesterol and other lipid disorders.

«Identifying specific signatures of ribonucleotide incorporation in DNA may represent novel biomarkers for human diseases such as cancer, and other degenerative disorders.»

In the new study, the researchers discovered that during the second trimester of human brain development, oRG cells express genes related to a fundamental signaling pathway called mTOR, defects in which have previously been implicated in autism and several other psychiatric disorders.

«Dysfunction of mitochondria outer membrane proteins are linked to disorders such as diabetes, Parkinsons and other neurodegenerative diseases, so we hope that this work may also help us to better understand these human diseases too.»

Unravelling this mechanism could also help scientists understand more about human cell dysfunctions linked to disorders such as diabetes, Parkinson's and other neurodegenerative diseases.

They verified that blood concentration levels were comparable to effective levels in humans being treated for bipolar disorder or mania, and then administered the open field and other behavioral tests.

The results suggest that this strategy could one day treat muscular dystrophy in humans as well as other genetic disorders.

Still, Dudley feels that evolutionary genetic analysis can help identify the most relevant genes and pathological mechanisms at play in schizophrenia and possibly other mental illnesses that preferentially affect humans — that is, neurodevelopmental disorders related to higher cognition and GABA activity, including autism and attention - deficit / hyperactivity disorder.

These so - called bioreactors, and the mini-brains they foster, should open other new and valuable windows into human brain development, brain disorders and drug testing — and perhaps even produce neurons for treatment of Parkinson's disease and other disorders, the investigators say.

The technique, carried out in living human cells and fruit flies, should help reveal how irregularities in protein synthesis contribute to developmental abnormalities and human disease processes including those involved in Alzheimer's disease and other memory - related disorders.

These findings could have implications for understanding the genetic basis of methamphetamine addiction in humans and the development of novel therapeutics for prevention and treatment of substance abuse and possibly other psychiatric disorders.

¿ - herpesviruses, which include the human oncogenic viruses Kaposi Sarcoma - associated herpesvirus (KSHV) and Epstein Barr virus (EBV), are a family of large double - stranded DNA lymphotrophic viruses that are the causative agents of a variety of disorders, including lymphoproliferative diseases, lymphomas, as well as other nonlymphoid cancers in mammals.

Gammaherpesviruses, which include the human oncogenic viruses Kaposi Sarcoma - associated herpesvirus (KSHV) and Epstein Barr virus (EBV), are a family of large double - stranded DNA lymphotrophic viruses that are the causative agents of a variety of disorders, including lymphoproliferative diseases, lymphomas, as well as other nonlymphoid cancers in mammals.

The Human Biochemical Genetics Section studies selected biochemical defects and other genetic disorders to provide insight into cellular mechanisms and to care for neglected groups of rare disease patients.

Animal gait is affected in models of human disorders such as Parkinson's Disease, Multiple Sclerosis, Amyotrophic Lateral Sclerosis, spinal cord injury and many others.

He and other researchers will now use TRN manipulation in mice whose brains mimic human disorders.

This noninvasive approach could pave the way to using optogenetics in human patients to treat epilepsy and other neurological disorders, the researchers say, although much more testing and development is needed.

From MIT Tech Review: «A new method for growing human brain cells could unlock the mysteries of dementia, mental illness, and other neurological disorders.»

But, the most important aspect of this discovery maybe its ability to possibly shed light on «a host of human neurological diseases, including dyslexia, schizophrenia and other disorders...»

Hennebold is attempting to create these «knockout» models for human diseases like hereditary blindness and deafness, among other disorders.

The recent Nature paper «High - throughput discovery of novel developmental phenotypes» describes the systematic high - throughput phenotyping screens used in the knock out mice and gives insight into a variety of gene function while a strong correlation was found between genes causing lethality in mice and genes causing diseases in humans, including cardiovascular defects, spina bifida, and metabolic disorders, among many others.