Researchers developed a new type of cell transplantation to treat mice mimicking a rare lung disease that one day could be used to treat this and
other human lung diseases caused by dysfunctional immune cells.
Not exact matches
Panoskaltsis - Mortari's team has been working on rebuilding
lungs and
other parts of the respiratory system using
human stem cells.
By printing multiple
lung airways — or any
other afflicted organ — from a
human patient and testing drugs on them, pharma companies can bypass the ethically challenged practice of testing on animals and proceed to
human clinical trials with greater confidence the drugs will actually work, according to Wadsworth.
I would like to repeat, the brain is just like any
other organ and just as capable of failing as a
human heart, a kidney or a
lung.
The police had nabbed Ajibade with a fresh
human head and
other body parts like hands,
lungs, liver and blood, which was kept inside a bottle during a stop and search operation in Osogbo, the state capital.
As it can take weeks to grow
human cells into intact differentiated and functional tissues within Organ Chips, such as those that mimic the
lung and intestine, and researchers seek to understand how drugs, toxins or
other perturbations alter tissue structure and function, the team at the Wyss Institute for Biologically Inspired Engineering led by Donald Ingber has been searching for ways to non-invasively monitor the health and maturity of cells cultured within these microfluidic devices over extended times.
As Paul Rozin, often called the «father of the psychology of disgust», has pointed out, we live in a world where the air we breathe comes from the
lungs of
other people, and contains molecules of animal and
human faeces.
She expects she will find laminum - 8 uniquely overexpressed in
other invasive cancers, like
lung and colon cancer, but to date she has tested for it in only
human brain and metastatic breast cancer.
In recent years, several groups of scientists have grown
lung cells from
human iPSCs, but the recipes aren't perfect — the resulting
lung cells grow amidst a jumble of liver cells, intestinal cells, and
other tissues.
All of these findings were supplemented with several
other experiments that were designed to learn how CHI3L1 interacts with
other cells involved in the tissue repair response in both
human and mouse
lungs.
By using molecular genetic tools to reduce the amount of PC in
human lung cancer cells, the team observed decreased cell growth, a compromised ability to form colonies in soft agar (a gelatinous material specifically used to grow bacteria and
other cells), and a reduced rate of tumor growth in mice.
The machines handle the decaying element's radiation better than
human miners and can tolerate the radon gas released by the ore; early Navajo miners of uranium in the U.S. — and their families exposed to residual radioactive dust and debris as well as contaminated water — developed
lung cancer and
other ailments by the 1970s and 1980s.
They also tested
other cancer lines —
human cervical,
lung and prostate cancers — and found that they responded to the patterned tumor environments in the same way.
The findings, now published in PLOS Genetics, reveal how mice can actually mimic
human breast cancer tissue and its genes, even more so than previously thought, as well as
other cancers including
lung, oral and esophagus.
Exposure in
humans can lead to heart disease, stroke,
lung cancer and
other health problems.
Because these receptors are mainly found deep inside the
human lung, patients developed very severe illness that frequently left them too sick to spread SARS to many
others; the people most at risk were health care workers who take care of patients.
Clevers and
other scientists have developed organoids of the gut, liver,
lung, brain, and many
other human organs that can be used to model disease or to serve as test beds for drugs.
«The development of this microfluidic
lung model, as well as
other organs - on - chip, holds the promise of improving the physiological relevance of cellular models for more accurate prediction of the effects of toxicants and drugs on
humans, and for reducing the use of animals in medical and pharmaceutical research,» said Sonia Grego, Ph.D., research scientist at RTI and the project's principal investigator.
Arsenic is a naturally occurring element that is toxic to
humans in some forms, and can cause skin,
lung and bladder cancers, and
other diseases.
Funding: NIH's National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), National Heart,
Lung, and Blood Institute (NHLBI), National Institute on Aging (NIA), National Center for Advancing Translational Sciences (NCATS), National Cancer Institute (NCI), and National
Human Genome Research Institute (NHGRI); and many
other funding entities (see reference paper for the full list).
The 19 NIH institutes, centers and offices contributing to the contracts are: National Center for Complementary and Alternative Medicine, National Center for Research Resources, National Eye Institute, National
Human Genome Research Institute, National Heart,
Lung and Blood Institute, National Institute on Aging, National Institute of Alcohol Abuse and Alcoholism, National Institute of Allergy and Infectious Diseases, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institute of Child Health and
Human Development, National Institute on Deafness and
Other Communication Disorders, National Institute of Dental and Craniofacial Research, National Institute on Drug Abuse, National Institute of Environmental Health Sciences, National Institute of General Medical Sciences, National Institute of Mental Health, National Institute of Neurological Disorders and Stroke, National Institute of Nursing Research, and the Office of AIDS Research.
To assess the expression of Tie2 and
other Ang / Tie signalling molecules on
human pericytes, a microarray - based expression profiling of
human brain pericytes (BP), placenta pericytes, pancreas pericytes (PA),
lung pericytes (LP), muscle pericytes (MP) and
human umbilical vein endothelial cells (HUVEC) was performed.
Previous studies have implicated FOXM1, which encodes a transcription factor protein capable of regulating the activity of many
other genes, in many
other human cancers, including liver, breast,
lung, prostate, colon, and pancreatic cancers.
The meeting will also feature
other aspects of the
Human Cell Atlas initiative, including updates on progress so far towards atlases of tumour,
lung, gut, kidney and immune system cells.
San Diego, CA (March 31, 2009)-- Novocell, Inc., a stem cell engineering company, today announced that it has received U.S. Patent 7,510,876 with claims covering
human definitive endoderm cells, an essential cell for generating not only pancreatic type cells, which Novocell is developing for use as a cell therapy for diabetes, but also
other endoderm lineage - derived tissues and organs such as
lungs, intestine, liver, thymus and thyroid.
However, they say the work at least proves the potential for mRNA therapy to successfully treat not only hemophilia B but also
other human disorders, such as hemophilia A (caused by faulty clotting factor VIII) or a variety of diseases of the liver, central nervous system,
lung and eyes.
In indigenous Australians and Papua New Guineans, mingling with the Denisovans (the «
other Neanderthal,» an ancestral
human living primarily in Asia) introduced genes related to «spermatogenesis, fertilization, cold acclimation, circadian rhythm, development of brain, neural tube, face, and olfactory pit, immunity,» as well as «female pregnancy, development of face,
lung, heart, skin, nervous system, and male gonad, visual and smell perception, response to heat, pain, hypoxia, and UV, lipid transport, metabolism, blood coagulation, wound healing, aging.»
Studies in animals and
humans have shown that dietary glutathione increases blood levels of glutathione, but one study in mice suggested that under ordinary conditions, dietary glutathione can not boost its own concentration in
other tissues except in the
lung, where large amounts of glutathione are needed to maintain the fluidity of mucus.
Released in theatres on August 24,1966, «Fantastic Voyage» was not only a film of authentic wonder but a science fiction masterpiece with amazing special effects... the team enters the body of a man where they see first hand the oceans of life within the
human body that contains the «corpuscles», «the heart», «the
lungs» and
other features of the
human body through which the crew move through are exquisitely designed in great detail with artistic quality.
Players will travel through veins, bones,
lungs, and every
other part of the
human body to eradicate the enemies.
Tinky is a beautiful kitty from Pennsylvania who lost her
human Mom to
lung cancer recently and was adopted by her Mom's loving Aunt, along with several
other pets.
AAHA, AVMA, AAFP, the Companion Animal Parasite Council (CAPC) and the Center for Disease Control (CDC) strongly recommend parasite control for companion animals for many reasons, including prevention of visceral larva migrans, a condition in which parasites within a
human «release larvae that migrate anywhere in the body... Organs commonly affected are the eye, brain, liver and
lung, where infections can cause permanent visual, neurologic, or
other tissue damage.
«Heartworm disease is a serious and potentially fatal condition caused by parasitic worms living in the arteries of the
lungs and occasionally in the right side of the heart of dogs, cats and
other species of mammals, including wolves, foxes, ferrets, sea lions and (in rare instances)
humans.
Heartworm disease is a preventable yet serious condition caused by parasitic worms living in the arteries of the
lungs, heart, and surrounding blood vessels of dogs, cats, wild canines and felines,
other mammal species, and in rare cases,
humans.
These may include internal organs not commonly eaten by
humans, such as
lungs, spleens, and intestines,
other parts such as cow udders and uteri, and in the case of poultry by - products, heads, beaks and feet.
The American
Lung Association recognizes that pollution from the combustion of wood and
other biomass sources poses a significant threat to
human health, and supports measures to transition away from using these products for heat production.
Sulfur dioxide (SO2): Produced when the sulfur in coal reacts with oxygen, SO2 combines with
other molecules in the atmosphere to form small, acidic particulates that can penetrate
human lungs.